Interactions for 1F9Q (chain D)
Structure details
- PDB ID: 1F9Q open_in_new
- Protein: CXCL4_HUMAN
- Organism: Homo sapiens
- UniProt ID: P02776 open_in_new
- Method: X-ray
- Resolution: 2.0 Å
- Date: Aug. 26, 2003
- Reference: open_in_new
- State: tetramer
Chemokine diagram
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Interactions found in structure
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| Chemokine Residue | Generic number | Segment | Partner Residue | Partner | Interaction Type |
|---|---|---|---|---|---|
| Asp 305 | 58 | N-term | LYS 14 | PLATELET FACTOR 4 (A) | HBAcceptor |
| Asp 305 | 58 | N-term | LYS 14 | PLATELET FACTOR 4 (A) | VdWContact |
| Gly 306 | 59 | N-term | LYS 14 | PLATELET FACTOR 4 (A) | HBAcceptor |
| Gly 306 | 59 | N-term | LYS 14 | PLATELET FACTOR 4 (A) | VdWContact |
| Asp 307 | 60 | N-term | VAL 13 | PLATELET FACTOR 4 (A) | HBAcceptor |
| Asp 307 | 60 | N-term | VAL 13 | PLATELET FACTOR 4 (A) | VdWContact |
| Asp 307 | 60 | N-term | CYS 12 | PLATELET FACTOR 4 (A) | VdWContact |
| Asp 307 | 60 | N-term | ILE 51 | PLATELET FACTOR 4 (A) | VdWContact |
| Asp 307 | 60 | N-term | THR 16 | PLATELET FACTOR 4 (A) | VdWContact |
| Asp 307 | 60 | N-term | CYS 52 | PLATELET FACTOR 4 (A) | Hydrophobic |
| Asp 307 | 60 | N-term | CYS 52 | PLATELET FACTOR 4 (A) | HBAcceptor |
| Asp 307 | 60 | N-term | CYS 52 | PLATELET FACTOR 4 (A) | VdWContact |
| Asp 307 | 60 | N-term | LYS 14 | PLATELET FACTOR 4 (A) | HBAcceptor |
| Asp 307 | 60 | N-term | LYS 14 | PLATELET FACTOR 4 (A) | Anionic |
| Asp 307 | 60 | N-term | LYS 14 | PLATELET FACTOR 4 (A) | VdWContact |
| Leu 308 | 61 | N-term | ILE 42 | PLATELET FACTOR 4 (A) | Hydrophobic |
| Leu 308 | 61 | N-term | LYS 50 | PLATELET FACTOR 4 (A) | Hydrophobic |
| Leu 308 | 61 | N-term | LEU 11 | PLATELET FACTOR 4 (A) | VdWContact |
| Gln 309 | 62 | N-term | VAL 13 | PLATELET FACTOR 4 (A) | Hydrophobic |
| Gln 309 | 62 | N-term | VAL 13 | PLATELET FACTOR 4 (A) | VdWContact |
| Gln 309 | 62 | N-term | CYS 10 | PLATELET FACTOR 4 (A) | HBDonor |
| Gln 309 | 62 | N-term | CYS 10 | PLATELET FACTOR 4 (A) | VdWContact |
| Gln 309 | 62 | N-term | LEU 11 | PLATELET FACTOR 4 (A) | HBDonor |
| Gln 309 | 62 | N-term | LEU 11 | PLATELET FACTOR 4 (A) | VdWContact |
| Cys 310 | 63 | CX | GLN 9 | PLATELET FACTOR 4 (A) | HBAcceptor |
| Cys 310 | 63 | CX | GLN 9 | PLATELET FACTOR 4 (A) | VdWContact |
| Leu 311 | 66 | CX | LEU 8 | PLATELET FACTOR 4 (A) | Hydrophobic |
| Leu 311 | 66 | CX | LEU 8 | PLATELET FACTOR 4 (A) | VdWContact |
| Leu 311 | 66 | CX | GLN 9 | PLATELET FACTOR 4 (A) | HBAcceptor |
| Leu 311 | 66 | CX | GLN 9 | PLATELET FACTOR 4 (A) | VdWContact |
| Leu 311 | 66 | CX | LEU 11 | PLATELET FACTOR 4 (A) | Hydrophobic |
| Leu 311 | 66 | CX | LEU 11 | PLATELET FACTOR 4 (A) | VdWContact |
| Val 313 | 68 | N-loop | ASP 7 | PLATELET FACTOR 4 (A) | HBDonor |
| Val 313 | 68 | N-loop | ASP 7 | PLATELET FACTOR 4 (A) | VdWContact |
| Val 313 | 68 | N-loop | GLN 9 | PLATELET FACTOR 4 (A) | Hydrophobic |
| Lys 314 | 69 | N-loop | ASP 7 | PLATELET FACTOR 4 (A) | VdWContact |
| Thr 316 | 71 | N-loop | ASP 7 | PLATELET FACTOR 4 (A) | VdWContact |
| Thr 325 | 84 | B1 | ASN 147 | PLATELET FACTOR 4 (B) | HBDonor |
| Thr 325 | 84 | B1 | ASN 147 | PLATELET FACTOR 4 (B) | VdWContact |
| Thr 325 | 84 | B1 | LYS 231 | PLATELET FACTOR 4 (C) | HBAcceptor |
| Thr 325 | 84 | B1 | LYS 231 | PLATELET FACTOR 4 (C) | VdWContact |
| Leu 327 | 86 | B1 | VAL 229 | PLATELET FACTOR 4 (C) | HBAcceptor |
| Leu 327 | 86 | B1 | VAL 229 | PLATELET FACTOR 4 (C) | HBDonor |
| Leu 327 | 86 | B1 | VAL 229 | PLATELET FACTOR 4 (C) | VdWContact |
| Leu 327 | 86 | B1 | GLU 228 | PLATELET FACTOR 4 (C) | VdWContact |
| Glu 328 | 87 | B1 | GLU 228 | PLATELET FACTOR 4 (C) | Hydrophobic |
| Glu 328 | 87 | B1 | LEU 227 | PLATELET FACTOR 4 (C) | VdWContact |
| Val 329 | 88 | B1 | LEU 267 | PLATELET FACTOR 4 (C) | Hydrophobic |
| Val 329 | 88 | B1 | LEU 227 | PLATELET FACTOR 4 (C) | HBAcceptor |
| Val 329 | 88 | B1 | LEU 227 | PLATELET FACTOR 4 (C) | HBDonor |
| Val 329 | 88 | B1 | LEU 227 | PLATELET FACTOR 4 (C) | VdWContact |
| Val 329 | 88 | B1 | SER 226 | PLATELET FACTOR 4 (C) | VdWContact |
| Lys 331 | 90 | 30s-loop | LYS 266 | PLATELET FACTOR 4 (C) | VdWContact |
| Lys 331 | 90 | 30s-loop | LEU 267 | PLATELET FACTOR 4 (C) | Hydrophobic |
| Lys 331 | 90 | 30s-loop | LEU 267 | PLATELET FACTOR 4 (C) | VdWContact |
| Lys 331 | 90 | 30s-loop | THR 225 | PLATELET FACTOR 4 (C) | HBDonor |
| Lys 331 | 90 | 30s-loop | THR 225 | PLATELET FACTOR 4 (C) | VdWContact |
| Ala 332 | 91 | 30s-loop | GLU 269 | PLATELET FACTOR 4 (C) | VdWContact |
| Ile 342 | 102 | B2 | LEU 8 | PLATELET FACTOR 4 (A) | Hydrophobic |
| Asn 347 | 112 | 40s-loop | LYS 146 | PLATELET FACTOR 4 (B) | VdWContact |
| Gly 348 | 113 | 40s-loop | LYS 146 | PLATELET FACTOR 4 (B) | VdWContact |
| Lys 350 | 115 | B3 | LEU 8 | PLATELET FACTOR 4 (A) | Hydrophobic |
| Ile 351 | 116 | B3 | ASP 7 | PLATELET FACTOR 4 (A) | Hydrophobic |
| Ile 351 | 116 | B3 | ASP 7 | PLATELET FACTOR 4 (A) | VdWContact |
| Cys 352 | 117 | B3 | ASP 7 | PLATELET FACTOR 4 (A) | HBDonor |
| Cys 352 | 117 | B3 | ASP 7 | PLATELET FACTOR 4 (A) | VdWContact |
| Tyr 360 | 125 | Helix | LEU 268 | PLATELET FACTOR 4 (C) | Hydrophobic |
| Tyr 360 | 125 | Helix | LEU 268 | PLATELET FACTOR 4 (C) | VdWContact |
| Tyr 360 | 125 | Helix | ILE 264 | PLATELET FACTOR 4 (C) | Hydrophobic |
| Ile 364 | 129 | Helix | ILE 264 | PLATELET FACTOR 4 (C) | Hydrophobic |
| Ile 364 | 129 | Helix | ILE 264 | PLATELET FACTOR 4 (C) | VdWContact |
| Lys 366 | 131 | Helix | LYS 231 | PLATELET FACTOR 4 (C) | VdWContact |
| Leu 367 | 132 | Helix | VAL 229 | PLATELET FACTOR 4 (C) | Hydrophobic |
| Leu 367 | 132 | Helix | ALA 239 | PLATELET FACTOR 4 (C) | VdWContact |
| Leu 367 | 132 | Helix | LYS 231 | PLATELET FACTOR 4 (C) | Hydrophobic |
| Leu 367 | 132 | Helix | LYS 231 | PLATELET FACTOR 4 (C) | VdWContact |
| Leu 368 | 133 | Helix | VAL 229 | PLATELET FACTOR 4 (C) | Hydrophobic |
| Leu 368 | 133 | Helix | VAL 229 | PLATELET FACTOR 4 (C) | VdWContact |
| Leu 368 | 133 | Helix | LEU 241 | PLATELET FACTOR 4 (C) | Hydrophobic |
| Leu 368 | 133 | Helix | LEU 241 | PLATELET FACTOR 4 (C) | VdWContact |
| Leu 368 | 133 | Helix | TYR 260 | PLATELET FACTOR 4 (C) | Hydrophobic |
| Leu 368 | 133 | Helix | TYR 260 | PLATELET FACTOR 4 (C) | VdWContact |
| Leu 368 | 133 | Helix | LEU 255 | PLATELET FACTOR 4 (C) | Hydrophobic |
| Leu 368 | 133 | Helix | LEU 255 | PLATELET FACTOR 4 (C) | VdWContact |
| Ser 370 | 135 | Helix | ALA 232 | PLATELET FACTOR 4 (C) | HBAcceptor |
| Ser 370 | 135 | Helix | ALA 232 | PLATELET FACTOR 4 (C) | VdWContact |
| Ser 370 | 135 | Helix | LYS 231 | PLATELET FACTOR 4 (C) | VdWContact |
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