Interactions for 1F9S (chain C)
Structure details
- PDB ID: 1F9S open_in_new
- Protein: CXCL4_HUMAN
- Organism: Homo sapiens
- UniProt ID: P02776 open_in_new
- Method: X-ray
- Resolution: 2.38 Å
- Date: Aug. 26, 2003
- Reference: open_in_new
- State: tetramer
Chemokine diagram
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Interactions found in structure
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| Chemokine Residue | Generic number | Segment | Partner Residue | Partner | Interaction Type |
|---|---|---|---|---|---|
| Gln 209 | 62 | N-term | CYS 152 | PLATELET FACTOR 4 (B) | VdWContact |
| Gln 209 | 62 | N-term | LYS 114 | PLATELET FACTOR 4 (B) | Hydrophobic |
| Gln 209 | 62 | N-term | THR 116 | PLATELET FACTOR 4 (B) | VdWContact |
| Gln 209 | 62 | N-term | ILE 151 | PLATELET FACTOR 4 (B) | VdWContact |
| Leu 211 | 66 | CX | LYS 150 | PLATELET FACTOR 4 (B) | Hydrophobic |
| Leu 211 | 66 | CX | LEU 111 | PLATELET FACTOR 4 (B) | Hydrophobic |
| Leu 211 | 66 | CX | LEU 111 | PLATELET FACTOR 4 (B) | VdWContact |
| Lys 214 | 69 | N-loop | VAL 113 | PLATELET FACTOR 4 (B) | VdWContact |
| Thr 225 | 84 | B1 | LYS 331 | PLATELET FACTOR 4 (D) | HBAcceptor |
| Thr 225 | 84 | B1 | LYS 331 | PLATELET FACTOR 4 (D) | VdWContact |
| Ser 226 | 85 | B1 | VAL 329 | PLATELET FACTOR 4 (D) | VdWContact |
| Leu 227 | 86 | B1 | VAL 329 | PLATELET FACTOR 4 (D) | Hydrophobic |
| Leu 227 | 86 | B1 | VAL 329 | PLATELET FACTOR 4 (D) | HBAcceptor |
| Leu 227 | 86 | B1 | VAL 329 | PLATELET FACTOR 4 (D) | HBDonor |
| Leu 227 | 86 | B1 | VAL 329 | PLATELET FACTOR 4 (D) | VdWContact |
| Glu 228 | 87 | B1 | LYS 150 | PLATELET FACTOR 4 (B) | HBAcceptor |
| Glu 228 | 87 | B1 | LYS 150 | PLATELET FACTOR 4 (B) | Anionic |
| Glu 228 | 87 | B1 | LYS 150 | PLATELET FACTOR 4 (B) | VdWContact |
| Glu 228 | 87 | B1 | SER 326 | PLATELET FACTOR 4 (D) | VdWContact |
| Glu 228 | 87 | B1 | GLU 328 | PLATELET FACTOR 4 (D) | Hydrophobic |
| Val 229 | 88 | B1 | LEU 368 | PLATELET FACTOR 4 (D) | Hydrophobic |
| Val 229 | 88 | B1 | LEU 368 | PLATELET FACTOR 4 (D) | VdWContact |
| Val 229 | 88 | B1 | ILE 364 | PLATELET FACTOR 4 (D) | Hydrophobic |
| Val 229 | 88 | B1 | LEU 367 | PLATELET FACTOR 4 (D) | Hydrophobic |
| Val 229 | 88 | B1 | SER 326 | PLATELET FACTOR 4 (D) | VdWContact |
| Val 229 | 88 | B1 | LEU 327 | PLATELET FACTOR 4 (D) | Hydrophobic |
| Val 229 | 88 | B1 | LEU 327 | PLATELET FACTOR 4 (D) | HBAcceptor |
| Val 229 | 88 | B1 | LEU 327 | PLATELET FACTOR 4 (D) | HBDonor |
| Val 229 | 88 | B1 | LEU 327 | PLATELET FACTOR 4 (D) | VdWContact |
| Ile 230 | 89 | B1 | LYS 150 | PLATELET FACTOR 4 (B) | Hydrophobic |
| Ile 230 | 89 | B1 | LYS 150 | PLATELET FACTOR 4 (B) | VdWContact |
| Lys 231 | 90 | 30s-loop | THR 325 | PLATELET FACTOR 4 (D) | HBDonor |
| Lys 231 | 90 | 30s-loop | THR 325 | PLATELET FACTOR 4 (D) | VdWContact |
| Lys 231 | 90 | 30s-loop | LEU 367 | PLATELET FACTOR 4 (D) | Hydrophobic |
| Lys 231 | 90 | 30s-loop | LEU 367 | PLATELET FACTOR 4 (D) | VdWContact |
| Ala 232 | 91 | 30s-loop | SER 370 | PLATELET FACTOR 4 (D) | VdWContact |
| His 235 | 94 | 30s-loop | LEU 145 | PLATELET FACTOR 4 (B) | Hydrophobic |
| His 235 | 94 | 30s-loop | ILE 151 | PLATELET FACTOR 4 (B) | Hydrophobic |
| His 235 | 94 | 30s-loop | ILE 151 | PLATELET FACTOR 4 (B) | VdWContact |
| Ala 239 | 99 | 30s-loop | LEU 368 | PLATELET FACTOR 4 (D) | Hydrophobic |
| Ala 239 | 99 | 30s-loop | SER 370 | PLATELET FACTOR 4 (D) | VdWContact |
| Leu 241 | 101 | B2 | LEU 368 | PLATELET FACTOR 4 (D) | Hydrophobic |
| Leu 241 | 101 | B2 | LEU 368 | PLATELET FACTOR 4 (D) | VdWContact |
| Ile 242 | 102 | B2 | LYS 150 | PLATELET FACTOR 4 (B) | Hydrophobic |
| Ile 242 | 102 | B2 | LEU 111 | PLATELET FACTOR 4 (B) | Hydrophobic |
| Lys 246 | 106 | 40s-loop | GLY 48 | PLATELET FACTOR 4 (A) | HBDonor |
| Lys 246 | 106 | 40s-loop | GLY 48 | PLATELET FACTOR 4 (A) | VdWContact |
| Asn 247 | 112 | 40s-loop | THR 25 | PLATELET FACTOR 4 (A) | HBAcceptor |
| Asn 247 | 112 | 40s-loop | THR 25 | PLATELET FACTOR 4 (A) | VdWContact |
| Lys 250 | 115 | B3 | LEU 111 | PLATELET FACTOR 4 (B) | Hydrophobic |
| Lys 250 | 115 | B3 | LEU 111 | PLATELET FACTOR 4 (B) | VdWContact |
| Lys 250 | 115 | B3 | GLU 128 | PLATELET FACTOR 4 (B) | Cationic |
| Lys 250 | 115 | B3 | GLU 128 | PLATELET FACTOR 4 (B) | VdWContact |
| Ile 251 | 116 | B3 | LEU 111 | PLATELET FACTOR 4 (B) | VdWContact |
| Cys 252 | 117 | B3 | LEU 111 | PLATELET FACTOR 4 (B) | Hydrophobic |
| Cys 252 | 117 | B3 | LEU 111 | PLATELET FACTOR 4 (B) | VdWContact |
| Leu 255 | 120 | 50s-loop | LEU 368 | PLATELET FACTOR 4 (D) | Hydrophobic |
| Leu 255 | 120 | 50s-loop | LEU 368 | PLATELET FACTOR 4 (D) | VdWContact |
| Tyr 260 | 125 | Helix | LEU 368 | PLATELET FACTOR 4 (D) | Hydrophobic |
| Ile 264 | 129 | Helix | ILE 364 | PLATELET FACTOR 4 (D) | Hydrophobic |
| Ile 264 | 129 | Helix | ILE 364 | PLATELET FACTOR 4 (D) | VdWContact |
| Leu 267 | 132 | Helix | LYS 331 | PLATELET FACTOR 4 (D) | Hydrophobic |
| Leu 267 | 132 | Helix | LYS 331 | PLATELET FACTOR 4 (D) | VdWContact |
| Leu 267 | 132 | Helix | VAL 329 | PLATELET FACTOR 4 (D) | Hydrophobic |
| Leu 268 | 133 | Helix | LEU 341 | PLATELET FACTOR 4 (D) | Hydrophobic |
| Leu 268 | 133 | Helix | LEU 341 | PLATELET FACTOR 4 (D) | VdWContact |
| Leu 268 | 133 | Helix | TYR 360 | PLATELET FACTOR 4 (D) | Hydrophobic |
| Leu 268 | 133 | Helix | TYR 360 | PLATELET FACTOR 4 (D) | VdWContact |
| Leu 268 | 133 | Helix | VAL 329 | PLATELET FACTOR 4 (D) | Hydrophobic |
| Leu 268 | 133 | Helix | ALA 339 | PLATELET FACTOR 4 (D) | Hydrophobic |
| Ser 270 | 135 | Helix | ALA 332 | PLATELET FACTOR 4 (D) | HBAcceptor |
| Ser 270 | 135 | Helix | ALA 332 | PLATELET FACTOR 4 (D) | VdWContact |
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