Interactions for 1NAP (chain A)
Structure details
- PDB ID: 1NAP open_in_new
- Protein: CXCL7_HUMAN
- Organism: Homo sapiens
- UniProt ID: P02775 open_in_new
- Method: X-ray
- Resolution: 1.9 Å
- Date: Dec. 19, 1995
- Reference: 10.1074/JBC.270.13.7077 open_in_new
- State: tetramer
Chemokine diagram
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Interactions found in structure
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| Chemokine Residue | Generic number | Segment | Partner Residue | Partner | Interaction Type |
|---|---|---|---|---|---|
| Arg 24 | 62 | N-term | ARG 64 | NEUTROPHIL ACTIVATING PEPTIDE-2 (C) | Hydrophobic |
| Met 26 | 66 | CX | ILE 57 | NEUTROPHIL ACTIVATING PEPTIDE-2 (C) | Hydrophobic |
| Met 26 | 66 | CX | LEU 26 | NEUTROPHIL ACTIVATING PEPTIDE-2 (C) | Hydrophobic |
| Met 26 | 66 | CX | LYS 65 | NEUTROPHIL ACTIVATING PEPTIDE-2 (C) | Hydrophobic |
| Met 26 | 66 | CX | LYS 65 | NEUTROPHIL ACTIVATING PEPTIDE-2 (C) | VdWContact |
| Gln 40 | 84 | B1 | GLY 46 | NEUTROPHIL ACTIVATING PEPTIDE-2 (B) | HBAcceptor |
| Gln 40 | 84 | B1 | GLY 46 | NEUTROPHIL ACTIVATING PEPTIDE-2 (B) | VdWContact |
| Ser 41 | 85 | B1 | VAL 44 | NEUTROPHIL ACTIVATING PEPTIDE-2 (B) | VdWContact |
| Leu 42 | 86 | B1 | VAL 44 | NEUTROPHIL ACTIVATING PEPTIDE-2 (B) | HBAcceptor |
| Leu 42 | 86 | B1 | VAL 44 | NEUTROPHIL ACTIVATING PEPTIDE-2 (B) | HBDonor |
| Leu 42 | 86 | B1 | VAL 44 | NEUTROPHIL ACTIVATING PEPTIDE-2 (B) | VdWContact |
| Leu 42 | 86 | B1 | GLU 43 | NEUTROPHIL ACTIVATING PEPTIDE-2 (B) | VdWContact |
| Glu 43 | 87 | B1 | GLU 43 | NEUTROPHIL ACTIVATING PEPTIDE-2 (B) | Hydrophobic |
| Glu 43 | 87 | B1 | LEU 42 | NEUTROPHIL ACTIVATING PEPTIDE-2 (B) | VdWContact |
| Glu 43 | 87 | B1 | LYS 65 | NEUTROPHIL ACTIVATING PEPTIDE-2 (C) | HBAcceptor |
| Glu 43 | 87 | B1 | LYS 65 | NEUTROPHIL ACTIVATING PEPTIDE-2 (C) | VdWContact |
| Val 44 | 88 | B1 | LYS 82 | NEUTROPHIL ACTIVATING PEPTIDE-2 (B) | Hydrophobic |
| Val 44 | 88 | B1 | LEU 83 | NEUTROPHIL ACTIVATING PEPTIDE-2 (B) | Hydrophobic |
| Val 44 | 88 | B1 | SER 41 | NEUTROPHIL ACTIVATING PEPTIDE-2 (B) | VdWContact |
| Val 44 | 88 | B1 | LEU 42 | NEUTROPHIL ACTIVATING PEPTIDE-2 (B) | Hydrophobic |
| Val 44 | 88 | B1 | LEU 42 | NEUTROPHIL ACTIVATING PEPTIDE-2 (B) | HBAcceptor |
| Val 44 | 88 | B1 | LEU 42 | NEUTROPHIL ACTIVATING PEPTIDE-2 (B) | HBDonor |
| Val 44 | 88 | B1 | LEU 42 | NEUTROPHIL ACTIVATING PEPTIDE-2 (B) | VdWContact |
| Ile 45 | 89 | B1 | LYS 65 | NEUTROPHIL ACTIVATING PEPTIDE-2 (C) | Hydrophobic |
| Gly 46 | 90 | 30s-loop | GLN 40 | NEUTROPHIL ACTIVATING PEPTIDE-2 (B) | HBDonor |
| Gly 46 | 90 | 30s-loop | GLN 40 | NEUTROPHIL ACTIVATING PEPTIDE-2 (B) | VdWContact |
| Gly 48 | 92 | 30s-loop | ARG 64 | NEUTROPHIL ACTIVATING PEPTIDE-2 (C) | VdWContact |
| Thr 49 | 93 | 30s-loop | ARG 64 | NEUTROPHIL ACTIVATING PEPTIDE-2 (C) | VdWContact |
| His 50 | 94 | 30s-loop | ARG 64 | NEUTROPHIL ACTIVATING PEPTIDE-2 (C) | HBAcceptor |
| His 50 | 94 | 30s-loop | ARG 64 | NEUTROPHIL ACTIVATING PEPTIDE-2 (C) | VdWContact |
| Val 54 | 99 | 30s-loop | GLY 85 | NEUTROPHIL ACTIVATING PEPTIDE-2 (B) | VdWContact |
| Val 56 | 101 | B2 | LEU 83 | NEUTROPHIL ACTIVATING PEPTIDE-2 (B) | Hydrophobic |
| Arg 64 | 114 | 40s-loop | HIS 50 | NEUTROPHIL ACTIVATING PEPTIDE-2 (C) | VdWContact |
| Arg 64 | 114 | 40s-loop | GLY 48 | NEUTROPHIL ACTIVATING PEPTIDE-2 (C) | VdWContact |
| Lys 65 | 115 | B3 | ILE 57 | NEUTROPHIL ACTIVATING PEPTIDE-2 (C) | Hydrophobic |
| Lys 65 | 115 | B3 | ILE 57 | NEUTROPHIL ACTIVATING PEPTIDE-2 (C) | VdWContact |
| Lys 65 | 115 | B3 | LEU 26 | NEUTROPHIL ACTIVATING PEPTIDE-2 (C) | Hydrophobic |
| Lys 65 | 115 | B3 | GLU 43 | NEUTROPHIL ACTIVATING PEPTIDE-2 (C) | Cationic |
| Lys 65 | 115 | B3 | GLU 43 | NEUTROPHIL ACTIVATING PEPTIDE-2 (C) | VdWContact |
| Lys 65 | 115 | B3 | ILE 45 | NEUTROPHIL ACTIVATING PEPTIDE-2 (C) | Hydrophobic |
| Lys 76 | 126 | Helix | LEU 83 | NEUTROPHIL ACTIVATING PEPTIDE-2 (B) | Hydrophobic |
| Lys 76 | 126 | Helix | GLN 80 | NEUTROPHIL ACTIVATING PEPTIDE-2 (B) | HBAcceptor |
| Lys 76 | 126 | Helix | GLN 80 | NEUTROPHIL ACTIVATING PEPTIDE-2 (B) | VdWContact |
| Val 79 | 129 | Helix | VAL 79 | NEUTROPHIL ACTIVATING PEPTIDE-2 (B) | Hydrophobic |
| Val 79 | 129 | Helix | LEU 83 | NEUTROPHIL ACTIVATING PEPTIDE-2 (B) | Hydrophobic |
| Val 79 | 129 | Helix | LEU 83 | NEUTROPHIL ACTIVATING PEPTIDE-2 (B) | VdWContact |
| Lys 82 | 132 | Helix | VAL 44 | NEUTROPHIL ACTIVATING PEPTIDE-2 (B) | Hydrophobic |
| Lys 82 | 132 | Helix | VAL 54 | NEUTROPHIL ACTIVATING PEPTIDE-2 (B) | VdWContact |
| Leu 83 | 133 | Helix | LYS 76 | NEUTROPHIL ACTIVATING PEPTIDE-2 (B) | Hydrophobic |
| Leu 83 | 133 | Helix | VAL 44 | NEUTROPHIL ACTIVATING PEPTIDE-2 (B) | Hydrophobic |
| Leu 83 | 133 | Helix | VAL 79 | NEUTROPHIL ACTIVATING PEPTIDE-2 (B) | Hydrophobic |
| Leu 83 | 133 | Helix | VAL 56 | NEUTROPHIL ACTIVATING PEPTIDE-2 (B) | Hydrophobic |
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