Interactions for 1PFM (chain A)
Structure details
- PDB ID: 1PFM open_in_new
- Protein: CXCL4_HUMAN
- Organism: Homo sapiens
- UniProt ID: P02776 open_in_new
- Method: Solution nmr
- Resolution: 0.0 Å
- Date: Jan. 29, 1996
- Reference: 10.1021/BI00036A012 open_in_new
- State: tetramer
Chemokine diagram
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Interactions found in structure
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| Chemokine Residue | Generic number | Segment | Partner Residue | Partner | Interaction Type |
|---|---|---|---|---|---|
| Gln 9 | 62 | N-term | GLN 11 | PF4-M2 CHIMERA (C) | HBDonor |
| Gln 9 | 62 | N-term | GLN 11 | PF4-M2 CHIMERA (C) | VdWContact |
| Gln 9 | 62 | N-term | CYS 12 | PF4-M2 CHIMERA (C) | VdWContact |
| Leu 11 | 66 | CX | GLN 11 | PF4-M2 CHIMERA (C) | Hydrophobic |
| Leu 11 | 66 | CX | GLN 11 | PF4-M2 CHIMERA (C) | VdWContact |
| Leu 11 | 66 | CX | LYS 50 | PF4-M2 CHIMERA (C) | VdWContact |
| Cys 12 | 67 | CX | ARG 9 | PF4-M2 CHIMERA (C) | Anionic |
| Val 13 | 68 | N-loop | ARG 9 | PF4-M2 CHIMERA (C) | VdWContact |
| Thr 16 | 71 | N-loop | ARG 9 | PF4-M2 CHIMERA (C) | HBAcceptor |
| Thr 16 | 71 | N-loop | ARG 9 | PF4-M2 CHIMERA (C) | VdWContact |
| Gln 18 | 74 | N-loop | GLU 7 | PF4-M2 CHIMERA (C) | Hydrophobic |
| Gln 18 | 74 | N-loop | GLU 7 | PF4-M2 CHIMERA (C) | VdWContact |
| Thr 25 | 84 | B1 | GLY 48 | PF4-M2 CHIMERA (D) | HBDonor |
| Thr 25 | 84 | B1 | GLY 48 | PF4-M2 CHIMERA (D) | VdWContact |
| Ser 26 | 85 | B1 | ILE 30 | PF4-M2 CHIMERA (B) | VdWContact |
| Leu 27 | 86 | B1 | VAL 29 | PF4-M2 CHIMERA (B) | HBAcceptor |
| Leu 27 | 86 | B1 | VAL 29 | PF4-M2 CHIMERA (B) | VdWContact |
| Val 29 | 88 | B1 | VAL 29 | PF4-M2 CHIMERA (B) | Hydrophobic |
| Val 29 | 88 | B1 | SER 26 | PF4-M2 CHIMERA (B) | VdWContact |
| Val 29 | 88 | B1 | LEU 67 | PF4-M2 CHIMERA (B) | Hydrophobic |
| Val 29 | 88 | B1 | LEU 67 | PF4-M2 CHIMERA (B) | VdWContact |
| Val 29 | 88 | B1 | LEU 27 | PF4-M2 CHIMERA (B) | HBAcceptor |
| Val 29 | 88 | B1 | LEU 27 | PF4-M2 CHIMERA (B) | HBDonor |
| Val 29 | 88 | B1 | LEU 27 | PF4-M2 CHIMERA (B) | VdWContact |
| Ile 30 | 89 | B1 | SER 26 | PF4-M2 CHIMERA (B) | VdWContact |
| Lys 31 | 90 | 30s-loop | LYS 66 | PF4-M2 CHIMERA (B) | VdWContact |
| Lys 31 | 90 | 30s-loop | LEU 67 | PF4-M2 CHIMERA (B) | Hydrophobic |
| Lys 31 | 90 | 30s-loop | LEU 67 | PF4-M2 CHIMERA (B) | VdWContact |
| Lys 31 | 90 | 30s-loop | SER 70 | PF4-M2 CHIMERA (B) | VdWContact |
| Lys 46 | 106 | 40s-loop | GLY 48 | PF4-M2 CHIMERA (D) | HBAcceptor |
| Lys 46 | 106 | 40s-loop | GLY 48 | PF4-M2 CHIMERA (D) | VdWContact |
| Gly 48 | 113 | 40s-loop | THR 25 | PF4-M2 CHIMERA (D) | HBAcceptor |
| Gly 48 | 113 | 40s-loop | THR 25 | PF4-M2 CHIMERA (D) | VdWContact |
| Gly 48 | 113 | 40s-loop | GLY 48 | PF4-M2 CHIMERA (D) | VdWContact |
| Gly 48 | 113 | 40s-loop | LYS 46 | PF4-M2 CHIMERA (D) | HBDonor |
| Gly 48 | 113 | 40s-loop | LYS 46 | PF4-M2 CHIMERA (D) | VdWContact |
| Arg 49 | 114 | 40s-loop | PRO 34 | PF4-M2 CHIMERA (C) | VdWContact |
| Lys 50 | 115 | B3 | GLU 28 | PF4-M2 CHIMERA (C) | Cationic |
| Leu 55 | 120 | 50s-loop | LEU 67 | PF4-M2 CHIMERA (B) | Hydrophobic |
| Tyr 60 | 125 | Helix | LEU 68 | PF4-M2 CHIMERA (B) | VdWContact |
| Ile 64 | 129 | Helix | ILE 64 | PF4-M2 CHIMERA (B) | Hydrophobic |
| Leu 67 | 132 | Helix | LYS 31 | PF4-M2 CHIMERA (B) | Hydrophobic |
| Leu 67 | 132 | Helix | LYS 31 | PF4-M2 CHIMERA (B) | VdWContact |
| Leu 67 | 132 | Helix | VAL 29 | PF4-M2 CHIMERA (B) | Hydrophobic |
| Leu 68 | 133 | Helix | TYR 60 | PF4-M2 CHIMERA (B) | VdWContact |
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