Interactions for 1PLF (chain B)


Structure details

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Chemokine diagram

G A G T H C P S P Q 30s-loop K T G R 40s-loop D Q Q R 50s-loopN-term E S S F P A T F V P L P A D S E G G E D E D L Q C V C L K T T S G I N P R H N-termC-term D E S C-term I V E L S S I L L A T K L C I K P L Y K K I L K K L L D G
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Interactions found in structure

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Chemokine Residue Generic number Segment Partner Residue Partner Interaction Type
Glu 21 59 N-term LYS 29 PLATELET FACTOR 4 (D) HBAcceptor
Glu 21 59 N-term LYS 29 PLATELET FACTOR 4 (D) Anionic
Glu 21 59 N-term LYS 29 PLATELET FACTOR 4 (D) VdWContact
Asp 22 60 N-term LEU 28 PLATELET FACTOR 4 (D) HBAcceptor
Asp 22 60 N-term LEU 28 PLATELET FACTOR 4 (D) VdWContact
Asp 22 60 N-term LYS 29 PLATELET FACTOR 4 (D) HBAcceptor
Asp 22 60 N-term LYS 29 PLATELET FACTOR 4 (D) VdWContact
Leu 23 61 N-term LYS 65 PLATELET FACTOR 4 (D) Hydrophobic
Leu 23 61 N-term VAL 26 PLATELET FACTOR 4 (D) Hydrophobic
Leu 23 61 N-term VAL 26 PLATELET FACTOR 4 (D) VdWContact
Leu 23 61 N-term CYS 67 PLATELET FACTOR 4 (D) Hydrophobic
Leu 23 61 N-term CYS 67 PLATELET FACTOR 4 (D) VdWContact
Gln 24 62 N-term CYS 25 PLATELET FACTOR 4 (D) HBDonor
Gln 24 62 N-term CYS 25 PLATELET FACTOR 4 (D) VdWContact
Gln 24 62 N-term LEU 28 PLATELET FACTOR 4 (D) Hydrophobic
Gln 24 62 N-term LEU 28 PLATELET FACTOR 4 (D) VdWContact
Gln 24 62 N-term VAL 26 PLATELET FACTOR 4 (D) HBDonor
Gln 24 62 N-term VAL 26 PLATELET FACTOR 4 (D) VdWContact
Cys 25 63 CX GLN 24 PLATELET FACTOR 4 (D) HBAcceptor
Cys 25 63 CX GLN 24 PLATELET FACTOR 4 (D) VdWContact
Val 26 66 CX LEU 23 PLATELET FACTOR 4 (D) Hydrophobic
Val 26 66 CX LEU 23 PLATELET FACTOR 4 (D) VdWContact
Val 26 66 CX VAL 26 PLATELET FACTOR 4 (D) Hydrophobic
Val 26 66 CX VAL 26 PLATELET FACTOR 4 (D) VdWContact
Val 26 66 CX GLN 24 PLATELET FACTOR 4 (D) HBAcceptor
Val 26 66 CX GLN 24 PLATELET FACTOR 4 (D) VdWContact
Leu 28 68 N-loop ASP 22 PLATELET FACTOR 4 (D) HBDonor
Leu 28 68 N-loop ASP 22 PLATELET FACTOR 4 (D) VdWContact
Leu 28 68 N-loop GLN 24 PLATELET FACTOR 4 (D) Hydrophobic
Leu 28 68 N-loop GLU 21 PLATELET FACTOR 4 (D) Hydrophobic
Leu 28 68 N-loop GLU 21 PLATELET FACTOR 4 (D) VdWContact
Lys 29 69 N-loop ASP 22 PLATELET FACTOR 4 (D) HBDonor
Lys 29 69 N-loop ASP 22 PLATELET FACTOR 4 (D) VdWContact
Lys 29 69 N-loop GLU 21 PLATELET FACTOR 4 (D) Hydrophobic
Lys 29 69 N-loop GLU 21 PLATELET FACTOR 4 (D) HBDonor
Lys 29 69 N-loop GLU 21 PLATELET FACTOR 4 (D) Cationic
Lys 29 69 N-loop GLU 21 PLATELET FACTOR 4 (D) VdWContact
Ser 40 84 B1 GLY 63 PLATELET FACTOR 4 (C) VdWContact
Ser 40 84 B1 GLY 46 PLATELET FACTOR 4 (A) HBAcceptor
Ser 40 84 B1 GLY 46 PLATELET FACTOR 4 (A) VdWContact
Ser 40 84 B1 THR 62 PLATELET FACTOR 4 (C) HBDonor
Ser 40 84 B1 THR 62 PLATELET FACTOR 4 (C) VdWContact
Ser 40 84 B1 ARG 64 PLATELET FACTOR 4 (C) VdWContact
Ser 41 85 B1 GLU 43 PLATELET FACTOR 4 (A) HBDonor
Ser 41 85 B1 GLU 43 PLATELET FACTOR 4 (A) VdWContact
Ser 41 85 B1 VAL 44 PLATELET FACTOR 4 (A) VdWContact
Leu 42 86 B1 GLU 43 PLATELET FACTOR 4 (A) VdWContact
Leu 42 86 B1 VAL 44 PLATELET FACTOR 4 (A) HBAcceptor
Leu 42 86 B1 VAL 44 PLATELET FACTOR 4 (A) HBDonor
Leu 42 86 B1 VAL 44 PLATELET FACTOR 4 (A) VdWContact
Glu 43 87 B1 GLU 43 PLATELET FACTOR 4 (A) Hydrophobic
Glu 43 87 B1 GLU 43 PLATELET FACTOR 4 (A) VdWContact
Glu 43 87 B1 LEU 42 PLATELET FACTOR 4 (A) VdWContact
Val 44 88 B1 LEU 82 PLATELET FACTOR 4 (A) Hydrophobic
Val 44 88 B1 LEU 42 PLATELET FACTOR 4 (A) HBAcceptor
Val 44 88 B1 LEU 42 PLATELET FACTOR 4 (A) HBDonor
Val 44 88 B1 LEU 42 PLATELET FACTOR 4 (A) VdWContact
Val 44 88 B1 SER 41 PLATELET FACTOR 4 (A) VdWContact
Val 44 88 B1 LEU 83 PLATELET FACTOR 4 (A) Hydrophobic
Gly 46 90 30s-loop SER 40 PLATELET FACTOR 4 (A) HBDonor
Gly 46 90 30s-loop SER 40 PLATELET FACTOR 4 (A) VdWContact
Pro 54 99 30s-loop SER 85 PLATELET FACTOR 4 (A) VdWContact
Pro 54 99 30s-loop LEU 82 PLATELET FACTOR 4 (A) VdWContact
Pro 54 99 30s-loop LEU 83 PLATELET FACTOR 4 (A) Hydrophobic
Leu 56 101 B2 LEU 83 PLATELET FACTOR 4 (A) Hydrophobic
Leu 57 102 B2 LEU 23 PLATELET FACTOR 4 (D) Hydrophobic
Gly 63 113 40s-loop LYS 61 PLATELET FACTOR 4 (C) VdWContact
Arg 64 114 40s-loop ASP 22 PLATELET FACTOR 4 (D) Cationic
Lys 65 115 B3 LEU 23 PLATELET FACTOR 4 (D) Hydrophobic
Gln 70 120 50s-loop LEU 83 PLATELET FACTOR 4 (A) Hydrophobic
Gln 70 120 50s-loop LEU 83 PLATELET FACTOR 4 (A) VdWContact
Tyr 75 125 Helix LEU 83 PLATELET FACTOR 4 (A) Hydrophobic
Leu 79 129 Helix ILE 79 PLATELET FACTOR 4 (A) Hydrophobic
Leu 79 129 Helix ILE 79 PLATELET FACTOR 4 (A) VdWContact
Leu 82 132 Helix PRO 54 PLATELET FACTOR 4 (A) VdWContact
Leu 82 132 Helix VAL 44 PLATELET FACTOR 4 (A) Hydrophobic
Leu 82 132 Helix VAL 44 PLATELET FACTOR 4 (A) VdWContact
Leu 83 133 Helix PRO 54 PLATELET FACTOR 4 (A) Hydrophobic
Leu 83 133 Helix PRO 54 PLATELET FACTOR 4 (A) VdWContact
Leu 83 133 Helix TYR 75 PLATELET FACTOR 4 (A) Hydrophobic
Leu 83 133 Helix GLN 70 PLATELET FACTOR 4 (A) Hydrophobic
Leu 83 133 Helix LEU 56 PLATELET FACTOR 4 (A) Hydrophobic
Leu 83 133 Helix LEU 56 PLATELET FACTOR 4 (A) VdWContact
Leu 83 133 Helix VAL 44 PLATELET FACTOR 4 (A) Hydrophobic
Ser 85 138 C-term PRO 52 PLATELET FACTOR 4 (A) HBDonor
Ser 85 138 C-term PRO 52 PLATELET FACTOR 4 (A) VdWContact

Ligand interaction network

TCN_D_1

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