Interactions for 1PLF (chain C)
Structure details
- PDB ID: 1PLF open_in_new
- Protein: CXCL4_BOVIN
- Organism: Bos taurus
- UniProt ID: P02777 open_in_new
- Method: X-ray
- Resolution: 2.2 Å
- Date: Jan. 31, 1994
- Reference: open_in_new
- State: tetramer
Chemokine diagram
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Interactions found in structure
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| Chemokine Residue | Generic number | Segment | Partner Residue | Partner | Interaction Type |
|---|---|---|---|---|---|
| Leu 23 | 61 | N-term | ILE 34 | PLATELET FACTOR 4 (A) | Hydrophobic |
| Leu 23 | 61 | N-term | ILE 66 | PLATELET FACTOR 4 (A) | Hydrophobic |
| Val 26 | 66 | CX | CYS 67 | PLATELET FACTOR 4 (A) | Hydrophobic |
| Val 26 | 66 | CX | CYS 67 | PLATELET FACTOR 4 (A) | VdWContact |
| Val 26 | 66 | CX | LYS 65 | PLATELET FACTOR 4 (A) | Hydrophobic |
| Val 26 | 66 | CX | VAL 26 | PLATELET FACTOR 4 (A) | Hydrophobic |
| Val 26 | 66 | CX | VAL 26 | PLATELET FACTOR 4 (A) | VdWContact |
| Leu 28 | 68 | N-loop | LEU 28 | PLATELET FACTOR 4 (A) | Hydrophobic |
| Leu 28 | 68 | N-loop | LYS 29 | PLATELET FACTOR 4 (A) | Hydrophobic |
| Lys 29 | 69 | N-loop | LEU 28 | PLATELET FACTOR 4 (A) | Hydrophobic |
| Lys 29 | 69 | N-loop | LEU 28 | PLATELET FACTOR 4 (A) | VdWContact |
| Thr 31 | 71 | N-loop | GLN 24 | PLATELET FACTOR 4 (A) | Hydrophobic |
| Thr 31 | 71 | N-loop | GLN 24 | PLATELET FACTOR 4 (A) | VdWContact |
| Ser 40 | 84 | B1 | GLY 46 | PLATELET FACTOR 4 (D) | HBAcceptor |
| Ser 40 | 84 | B1 | GLY 46 | PLATELET FACTOR 4 (D) | VdWContact |
| Ser 41 | 85 | B1 | VAL 44 | PLATELET FACTOR 4 (D) | VdWContact |
| Leu 42 | 86 | B1 | VAL 44 | PLATELET FACTOR 4 (D) | HBAcceptor |
| Leu 42 | 86 | B1 | VAL 44 | PLATELET FACTOR 4 (D) | HBDonor |
| Leu 42 | 86 | B1 | VAL 44 | PLATELET FACTOR 4 (D) | VdWContact |
| Leu 42 | 86 | B1 | GLU 43 | PLATELET FACTOR 4 (D) | VdWContact |
| Glu 43 | 87 | B1 | LYS 65 | PLATELET FACTOR 4 (A) | HBAcceptor |
| Glu 43 | 87 | B1 | LYS 65 | PLATELET FACTOR 4 (A) | Anionic |
| Glu 43 | 87 | B1 | LYS 65 | PLATELET FACTOR 4 (A) | VdWContact |
| Glu 43 | 87 | B1 | LEU 42 | PLATELET FACTOR 4 (D) | VdWContact |
| Val 44 | 88 | B1 | LEU 83 | PLATELET FACTOR 4 (D) | Hydrophobic |
| Val 44 | 88 | B1 | LEU 82 | PLATELET FACTOR 4 (D) | Hydrophobic |
| Val 44 | 88 | B1 | LEU 42 | PLATELET FACTOR 4 (D) | HBAcceptor |
| Val 44 | 88 | B1 | LEU 42 | PLATELET FACTOR 4 (D) | HBDonor |
| Val 44 | 88 | B1 | LEU 42 | PLATELET FACTOR 4 (D) | VdWContact |
| Val 44 | 88 | B1 | SER 41 | PLATELET FACTOR 4 (D) | VdWContact |
| Ile 45 | 89 | B1 | LYS 65 | PLATELET FACTOR 4 (A) | Hydrophobic |
| Gly 46 | 90 | 30s-loop | SER 40 | PLATELET FACTOR 4 (D) | HBDonor |
| Gly 46 | 90 | 30s-loop | SER 40 | PLATELET FACTOR 4 (D) | VdWContact |
| His 50 | 94 | 30s-loop | ARG 64 | PLATELET FACTOR 4 (A) | Hydrophobic |
| His 50 | 94 | 30s-loop | ARG 64 | PLATELET FACTOR 4 (A) | VdWContact |
| Pro 54 | 99 | 30s-loop | LEU 83 | PLATELET FACTOR 4 (D) | VdWContact |
| Pro 54 | 99 | 30s-loop | LEU 82 | PLATELET FACTOR 4 (D) | VdWContact |
| Leu 56 | 101 | B2 | LEU 83 | PLATELET FACTOR 4 (D) | Hydrophobic |
| Leu 56 | 101 | B2 | LEU 83 | PLATELET FACTOR 4 (D) | VdWContact |
| Leu 57 | 102 | B2 | LYS 65 | PLATELET FACTOR 4 (A) | Hydrophobic |
| Lys 60 | 105 | B2 | HIS 50 | PLATELET FACTOR 4 (A) | Hydrophobic |
| Lys 61 | 106 | 40s-loop | GLY 63 | PLATELET FACTOR 4 (B) | VdWContact |
| Thr 62 | 112 | 40s-loop | SER 40 | PLATELET FACTOR 4 (B) | HBAcceptor |
| Thr 62 | 112 | 40s-loop | SER 40 | PLATELET FACTOR 4 (B) | VdWContact |
| Gly 63 | 113 | 40s-loop | SER 40 | PLATELET FACTOR 4 (B) | VdWContact |
| Arg 64 | 114 | 40s-loop | GLY 46 | PLATELET FACTOR 4 (A) | VdWContact |
| Arg 64 | 114 | 40s-loop | SER 40 | PLATELET FACTOR 4 (B) | VdWContact |
| Arg 64 | 114 | 40s-loop | HIS 50 | PLATELET FACTOR 4 (A) | Hydrophobic |
| Arg 64 | 114 | 40s-loop | HIS 50 | PLATELET FACTOR 4 (A) | VdWContact |
| Lys 65 | 115 | B3 | GLU 43 | PLATELET FACTOR 4 (A) | Cationic |
| Lys 65 | 115 | B3 | GLU 43 | PLATELET FACTOR 4 (A) | VdWContact |
| Lys 65 | 115 | B3 | ILE 45 | PLATELET FACTOR 4 (A) | Hydrophobic |
| Lys 65 | 115 | B3 | ILE 57 | PLATELET FACTOR 4 (A) | Hydrophobic |
| Lys 65 | 115 | B3 | VAL 26 | PLATELET FACTOR 4 (A) | Hydrophobic |
| Ile 66 | 116 | B3 | GLN 24 | PLATELET FACTOR 4 (A) | Hydrophobic |
| Ile 66 | 116 | B3 | GLN 24 | PLATELET FACTOR 4 (A) | VdWContact |
| Tyr 75 | 125 | Helix | LEU 83 | PLATELET FACTOR 4 (D) | Hydrophobic |
| Leu 82 | 132 | Helix | VAL 44 | PLATELET FACTOR 4 (D) | Hydrophobic |
| Leu 83 | 133 | Helix | TYR 75 | PLATELET FACTOR 4 (D) | Hydrophobic |
| Leu 83 | 133 | Helix | VAL 44 | PLATELET FACTOR 4 (D) | Hydrophobic |
| Leu 83 | 133 | Helix | LEU 56 | PLATELET FACTOR 4 (D) | Hydrophobic |
| Leu 83 | 133 | Helix | LEU 56 | PLATELET FACTOR 4 (D) | VdWContact |
| Leu 83 | 133 | Helix | GLN 70 | PLATELET FACTOR 4 (D) | HBAcceptor |
| Leu 83 | 133 | Helix | GLN 70 | PLATELET FACTOR 4 (D) | VdWContact |
Ligand interaction network
TCN_D_1
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