Interactions for 1RHP (chain B)
Structure details
- PDB ID: 1RHP open_in_new
- Protein: CXCL4_HUMAN
- Organism: Homo sapiens
- UniProt ID: P02776 open_in_new
- Method: X-ray
- Resolution: 2.4 Å
- Date: Nov. 30, 1994
- Reference: 10.1021/BI00193A025 open_in_new
- State: tetramer
Chemokine diagram
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Interactions found in structure
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| Chemokine Residue | Generic number | Segment | Partner Residue | Partner | Interaction Type |
|---|---|---|---|---|---|
| Asp 7 | 60 | N-term | VAL 13 | PLATELET FACTOR 4 (D) | Hydrophobic |
| Asp 7 | 60 | N-term | VAL 13 | PLATELET FACTOR 4 (D) | VdWContact |
| Asp 7 | 60 | N-term | CYS 52 | PLATELET FACTOR 4 (D) | VdWContact |
| Asp 7 | 60 | N-term | LYS 14 | PLATELET FACTOR 4 (D) | Anionic |
| Leu 8 | 61 | N-term | VAL 13 | PLATELET FACTOR 4 (D) | Hydrophobic |
| Leu 8 | 61 | N-term | VAL 13 | PLATELET FACTOR 4 (D) | VdWContact |
| Gln 9 | 62 | N-term | VAL 13 | PLATELET FACTOR 4 (D) | Hydrophobic |
| Gln 9 | 62 | N-term | VAL 13 | PLATELET FACTOR 4 (D) | VdWContact |
| Gln 9 | 62 | N-term | CYS 10 | PLATELET FACTOR 4 (D) | VdWContact |
| Gln 9 | 62 | N-term | LEU 11 | PLATELET FACTOR 4 (D) | HBDonor |
| Gln 9 | 62 | N-term | LEU 11 | PLATELET FACTOR 4 (D) | VdWContact |
| Cys 10 | 63 | CX | GLN 9 | PLATELET FACTOR 4 (D) | HBAcceptor |
| Cys 10 | 63 | CX | GLN 9 | PLATELET FACTOR 4 (D) | VdWContact |
| Leu 11 | 66 | CX | LEU 8 | PLATELET FACTOR 4 (D) | Hydrophobic |
| Leu 11 | 66 | CX | LEU 8 | PLATELET FACTOR 4 (D) | VdWContact |
| Leu 11 | 66 | CX | GLN 9 | PLATELET FACTOR 4 (D) | HBAcceptor |
| Leu 11 | 66 | CX | GLN 9 | PLATELET FACTOR 4 (D) | VdWContact |
| Leu 11 | 66 | CX | LEU 11 | PLATELET FACTOR 4 (D) | Hydrophobic |
| Leu 11 | 66 | CX | LEU 11 | PLATELET FACTOR 4 (D) | VdWContact |
| Val 13 | 68 | N-loop | ASP 7 | PLATELET FACTOR 4 (D) | HBDonor |
| Val 13 | 68 | N-loop | ASP 7 | PLATELET FACTOR 4 (D) | VdWContact |
| Val 13 | 68 | N-loop | GLN 9 | PLATELET FACTOR 4 (D) | Hydrophobic |
| Lys 14 | 69 | N-loop | ASP 7 | PLATELET FACTOR 4 (D) | HBDonor |
| Lys 14 | 69 | N-loop | ASP 7 | PLATELET FACTOR 4 (D) | VdWContact |
| Thr 25 | 84 | B1 | LYS 31 | PLATELET FACTOR 4 (A) | Hydrophobic |
| Thr 25 | 84 | B1 | LYS 31 | PLATELET FACTOR 4 (A) | HBAcceptor |
| Thr 25 | 84 | B1 | LYS 31 | PLATELET FACTOR 4 (A) | VdWContact |
| Thr 25 | 84 | B1 | ASN 47 | PLATELET FACTOR 4 (C) | HBDonor |
| Thr 25 | 84 | B1 | ASN 47 | PLATELET FACTOR 4 (C) | VdWContact |
| Ser 26 | 85 | B1 | ILE 30 | PLATELET FACTOR 4 (A) | VdWContact |
| Leu 27 | 86 | B1 | VAL 29 | PLATELET FACTOR 4 (A) | HBAcceptor |
| Leu 27 | 86 | B1 | VAL 29 | PLATELET FACTOR 4 (A) | VdWContact |
| Glu 28 | 87 | B1 | LEU 27 | PLATELET FACTOR 4 (A) | VdWContact |
| Glu 28 | 87 | B1 | GLU 28 | PLATELET FACTOR 4 (A) | Hydrophobic |
| Val 29 | 88 | B1 | LEU 67 | PLATELET FACTOR 4 (A) | Hydrophobic |
| Val 29 | 88 | B1 | LEU 27 | PLATELET FACTOR 4 (A) | HBAcceptor |
| Val 29 | 88 | B1 | LEU 27 | PLATELET FACTOR 4 (A) | HBDonor |
| Val 29 | 88 | B1 | LEU 27 | PLATELET FACTOR 4 (A) | VdWContact |
| Val 29 | 88 | B1 | SER 26 | PLATELET FACTOR 4 (A) | VdWContact |
| Val 29 | 88 | B1 | LEU 68 | PLATELET FACTOR 4 (A) | Hydrophobic |
| Val 29 | 88 | B1 | LEU 68 | PLATELET FACTOR 4 (A) | VdWContact |
| Lys 31 | 90 | 30s-loop | LEU 67 | PLATELET FACTOR 4 (A) | Hydrophobic |
| Lys 31 | 90 | 30s-loop | LEU 67 | PLATELET FACTOR 4 (A) | VdWContact |
| Lys 31 | 90 | 30s-loop | THR 25 | PLATELET FACTOR 4 (A) | HBDonor |
| Lys 31 | 90 | 30s-loop | THR 25 | PLATELET FACTOR 4 (A) | VdWContact |
| Lys 31 | 90 | 30s-loop | LYS 46 | PLATELET FACTOR 4 (A) | VdWContact |
| Leu 41 | 101 | B2 | LEU 68 | PLATELET FACTOR 4 (A) | Hydrophobic |
| Leu 41 | 101 | B2 | LEU 68 | PLATELET FACTOR 4 (A) | VdWContact |
| Arg 49 | 114 | 40s-loop | PRO 34 | PLATELET FACTOR 4 (D) | Hydrophobic |
| Lys 50 | 115 | B3 | LEU 8 | PLATELET FACTOR 4 (D) | Hydrophobic |
| Lys 50 | 115 | B3 | LEU 8 | PLATELET FACTOR 4 (D) | VdWContact |
| Leu 55 | 120 | 50s-loop | LEU 68 | PLATELET FACTOR 4 (A) | Hydrophobic |
| Tyr 60 | 125 | Helix | LEU 68 | PLATELET FACTOR 4 (A) | Hydrophobic |
| Tyr 60 | 125 | Helix | LEU 68 | PLATELET FACTOR 4 (A) | VdWContact |
| Ile 64 | 129 | Helix | ILE 64 | PLATELET FACTOR 4 (A) | Hydrophobic |
| Leu 67 | 132 | Helix | VAL 29 | PLATELET FACTOR 4 (A) | Hydrophobic |
| Leu 67 | 132 | Helix | LYS 31 | PLATELET FACTOR 4 (A) | Hydrophobic |
| Leu 67 | 132 | Helix | LYS 31 | PLATELET FACTOR 4 (A) | VdWContact |
| Leu 68 | 133 | Helix | TYR 60 | PLATELET FACTOR 4 (A) | Hydrophobic |
| Leu 68 | 133 | Helix | LEU 41 | PLATELET FACTOR 4 (A) | Hydrophobic |
| Leu 68 | 133 | Helix | LEU 41 | PLATELET FACTOR 4 (A) | VdWContact |
| Leu 68 | 133 | Helix | VAL 29 | PLATELET FACTOR 4 (A) | Hydrophobic |
| Leu 68 | 133 | Helix | LEU 55 | PLATELET FACTOR 4 (A) | Hydrophobic |
| Ser 70 | 135 | Helix | ALA 32 | PLATELET FACTOR 4 (A) | HBAcceptor |
| Ser 70 | 135 | Helix | ALA 32 | PLATELET FACTOR 4 (A) | VdWContact |
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