Interactions for 4HSV (chain C)
Structure details
- PDB ID: 4HSV open_in_new
- Protein: CXCL4L1_HUMAN
- Organism: Homo sapiens
- UniProt ID: P10720 open_in_new
- Method: X-ray
- Resolution: 2.08 Å
- Date: April 10, 2013
- Reference: 10.1074/JBC.M113.455329 open_in_new
- State: tetramer
Chemokine diagram
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Interactions found in structure
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| Chemokine Residue | Generic number | Segment | Partner Residue | Partner | Interaction Type |
|---|---|---|---|---|---|
| Leu 11 | 66 | CX | LEU 11 | Platelet factor 4 variant (B) | Hydrophobic |
| Leu 11 | 66 | CX | LEU 11 | Platelet factor 4 variant (B) | VdWContact |
| Leu 11 | 66 | CX | LYS 50 | Platelet factor 4 variant (B) | Hydrophobic |
| Leu 11 | 66 | CX | LYS 50 | Platelet factor 4 variant (B) | VdWContact |
| Leu 11 | 66 | CX | ILE 42 | Platelet factor 4 variant (B) | Hydrophobic |
| Val 13 | 68 | N-loop | VAL 13 | Platelet factor 4 variant (B) | Hydrophobic |
| Val 13 | 68 | N-loop | VAL 13 | Platelet factor 4 variant (B) | VdWContact |
| Pro 21 | 80 | N-loop | LYS 31 | Platelet factor 4 variant (D) | VdWContact |
| Ile 24 | 83 | B1 | LYS 31 | Platelet factor 4 variant (D) | Hydrophobic |
| Ile 24 | 83 | B1 | LYS 31 | Platelet factor 4 variant (D) | HBAcceptor |
| Ile 24 | 83 | B1 | LYS 31 | Platelet factor 4 variant (D) | VdWContact |
| Thr 25 | 84 | B1 | LYS 31 | Platelet factor 4 variant (D) | HBAcceptor |
| Thr 25 | 84 | B1 | LYS 31 | Platelet factor 4 variant (D) | VdWContact |
| Ser 26 | 85 | B1 | GLU 28 | Platelet factor 4 variant (D) | HBDonor |
| Ser 26 | 85 | B1 | GLU 28 | Platelet factor 4 variant (D) | VdWContact |
| Leu 27 | 86 | B1 | VAL 29 | Platelet factor 4 variant (D) | HBAcceptor |
| Leu 27 | 86 | B1 | VAL 29 | Platelet factor 4 variant (D) | HBDonor |
| Leu 27 | 86 | B1 | VAL 29 | Platelet factor 4 variant (D) | VdWContact |
| Leu 27 | 86 | B1 | GLU 28 | Platelet factor 4 variant (D) | VdWContact |
| Glu 28 | 87 | B1 | LYS 50 | Platelet factor 4 variant (B) | Anionic |
| Glu 28 | 87 | B1 | LYS 50 | Platelet factor 4 variant (B) | VdWContact |
| Glu 28 | 87 | B1 | SER 26 | Platelet factor 4 variant (D) | HBAcceptor |
| Glu 28 | 87 | B1 | SER 26 | Platelet factor 4 variant (D) | VdWContact |
| Glu 28 | 87 | B1 | LEU 27 | Platelet factor 4 variant (D) | VdWContact |
| Glu 28 | 87 | B1 | GLU 28 | Platelet factor 4 variant (D) | Hydrophobic |
| Glu 28 | 87 | B1 | GLU 28 | Platelet factor 4 variant (D) | VdWContact |
| Val 29 | 88 | B1 | LEU 27 | Platelet factor 4 variant (D) | Hydrophobic |
| Val 29 | 88 | B1 | LEU 27 | Platelet factor 4 variant (D) | HBAcceptor |
| Val 29 | 88 | B1 | LEU 27 | Platelet factor 4 variant (D) | HBDonor |
| Val 29 | 88 | B1 | LEU 27 | Platelet factor 4 variant (D) | VdWContact |
| Val 29 | 88 | B1 | SER 26 | Platelet factor 4 variant (D) | VdWContact |
| Ile 30 | 89 | B1 | LYS 50 | Platelet factor 4 variant (B) | Hydrophobic |
| Lys 31 | 90 | 30s-loop | ILE 24 | Platelet factor 4 variant (D) | VdWContact |
| Lys 31 | 90 | 30s-loop | THR 25 | Platelet factor 4 variant (D) | HBDonor |
| Lys 31 | 90 | 30s-loop | THR 25 | Platelet factor 4 variant (D) | VdWContact |
| His 35 | 94 | 30s-loop | ARG 49 | Platelet factor 4 variant (B) | PiCation |
| His 35 | 94 | 30s-loop | ARG 49 | Platelet factor 4 variant (B) | VdWContact |
| Ile 42 | 102 | B2 | LEU 11 | Platelet factor 4 variant (B) | Hydrophobic |
| Lys 46 | 106 | 40s-loop | GLY 48 | Platelet factor 4 variant (A) | VdWContact |
| Asn 47 | 112 | 40s-loop | THR 25 | Platelet factor 4 variant (A) | HBAcceptor |
| Asn 47 | 112 | 40s-loop | THR 25 | Platelet factor 4 variant (A) | VdWContact |
| Arg 49 | 114 | 40s-loop | HIS 35 | Platelet factor 4 variant (B) | CationPi |
| Arg 49 | 114 | 40s-loop | HIS 35 | Platelet factor 4 variant (B) | VdWContact |
| Lys 50 | 115 | B3 | GLU 28 | Platelet factor 4 variant (B) | Cationic |
| Lys 50 | 115 | B3 | GLU 28 | Platelet factor 4 variant (B) | VdWContact |
| Lys 50 | 115 | B3 | LEU 11 | Platelet factor 4 variant (B) | Hydrophobic |
| Lys 50 | 115 | B3 | LEU 11 | Platelet factor 4 variant (B) | VdWContact |
| Lys 50 | 115 | B3 | ILE 30 | Platelet factor 4 variant (B) | Hydrophobic |
| Lys 50 | 115 | B3 | ILE 42 | Platelet factor 4 variant (B) | Hydrophobic |
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