Interactions for 4R9W (chain A)
Structure details
- PDB ID: 4R9W open_in_new
- Protein: CXCL4_HUMAN
- Organism: Homo sapiens
- UniProt ID: P02776 open_in_new
- Method: X-ray
- Resolution: 2.5 Å
- Date: Dec. 16, 2015
- Reference: 10.1038/NCOMMS9277 open_in_new
- State: dimer
Chemokine diagram
Pick color:
, 'snake_.png', {scale: 3});){kind=link}
, 'snake_.jpg', {scale: 3});){kind=link}
Interactions found in structure
Download list in excel
| Chemokine Residue | Generic number | Segment | Partner Residue | Partner | Interaction Type |
|---|---|---|---|---|---|
| Thr 25 | 84 | B1 | LYS 131 | Platelet factor 4 (B) | HBAcceptor |
| Thr 25 | 84 | B1 | LYS 131 | Platelet factor 4 (B) | VdWContact |
| Ser 26 | 85 | B1 | VAL 129 | Platelet factor 4 (B) | VdWContact |
| Leu 27 | 86 | B1 | VAL 129 | Platelet factor 4 (B) | HBAcceptor |
| Leu 27 | 86 | B1 | VAL 129 | Platelet factor 4 (B) | HBDonor |
| Leu 27 | 86 | B1 | VAL 129 | Platelet factor 4 (B) | VdWContact |
| Glu 28 | 87 | B1 | LEU 127 | Platelet factor 4 (B) | VdWContact |
| Glu 28 | 87 | B1 | GLU 128 | Platelet factor 4 (B) | Hydrophobic |
| Glu 28 | 87 | B1 | GLU 128 | Platelet factor 4 (B) | VdWContact |
| Glu 28 | 87 | B1 | SER 126 | Platelet factor 4 (B) | VdWContact |
| Val 29 | 88 | B1 | ILE 164 | Platelet factor 4 (B) | Hydrophobic |
| Val 29 | 88 | B1 | LEU 167 | Platelet factor 4 (B) | Hydrophobic |
| Val 29 | 88 | B1 | LEU 127 | Platelet factor 4 (B) | HBAcceptor |
| Val 29 | 88 | B1 | LEU 127 | Platelet factor 4 (B) | HBDonor |
| Val 29 | 88 | B1 | LEU 127 | Platelet factor 4 (B) | VdWContact |
| Val 29 | 88 | B1 | SER 126 | Platelet factor 4 (B) | VdWContact |
| Val 29 | 88 | B1 | LEU 168 | Platelet factor 4 (B) | Hydrophobic |
| Lys 31 | 90 | 30s-loop | THR 125 | Platelet factor 4 (B) | Hydrophobic |
| Lys 31 | 90 | 30s-loop | THR 125 | Platelet factor 4 (B) | HBDonor |
| Lys 31 | 90 | 30s-loop | THR 125 | Platelet factor 4 (B) | VdWContact |
| Lys 31 | 90 | 30s-loop | LEU 167 | Platelet factor 4 (B) | Hydrophobic |
| Lys 31 | 90 | 30s-loop | LEU 167 | Platelet factor 4 (B) | VdWContact |
| Lys 31 | 90 | 30s-loop | UNL 1 | fondaparinux (None) | HBAcceptor |
| Lys 31 | 90 | 30s-loop | UNL 1 | fondaparinux (None) | Anionic |
| Lys 31 | 90 | 30s-loop | UNL 1 | fondaparinux (None) | VdWContact |
| Ala 32 | 91 | 30s-loop | SER 170 | Platelet factor 4 (B) | HBDonor |
| Ala 32 | 91 | 30s-loop | SER 170 | Platelet factor 4 (B) | VdWContact |
| His 35 | 94 | 30s-loop | UNL 1 | fondaparinux (None) | HBAcceptor |
| His 35 | 94 | 30s-loop | UNL 1 | fondaparinux (None) | VdWContact |
| Ala 39 | 99 | 30s-loop | LEU 168 | Platelet factor 4 (B) | VdWContact |
| Ala 39 | 99 | 30s-loop | LEU 167 | Platelet factor 4 (B) | VdWContact |
| Leu 41 | 101 | B2 | LEU 168 | Platelet factor 4 (B) | Hydrophobic |
| Leu 55 | 120 | 50s-loop | LEU 168 | Platelet factor 4 (B) | Hydrophobic |
| Tyr 60 | 125 | Helix | LEU 168 | Platelet factor 4 (B) | Hydrophobic |
| Tyr 60 | 125 | Helix | LEU 168 | Platelet factor 4 (B) | VdWContact |
| Ile 64 | 129 | Helix | VAL 129 | Platelet factor 4 (B) | Hydrophobic |
| Ile 64 | 129 | Helix | ILE 164 | Platelet factor 4 (B) | Hydrophobic |
| Ile 64 | 129 | Helix | ILE 164 | Platelet factor 4 (B) | VdWContact |
| Leu 67 | 132 | Helix | VAL 129 | Platelet factor 4 (B) | Hydrophobic |
| Leu 67 | 132 | Helix | LYS 131 | Platelet factor 4 (B) | Hydrophobic |
| Leu 67 | 132 | Helix | LYS 131 | Platelet factor 4 (B) | VdWContact |
| Leu 68 | 133 | Helix | VAL 129 | Platelet factor 4 (B) | Hydrophobic |
| Leu 68 | 133 | Helix | TYR 160 | Platelet factor 4 (B) | Hydrophobic |
| Leu 68 | 133 | Helix | TYR 160 | Platelet factor 4 (B) | VdWContact |
| Leu 68 | 133 | Helix | ALA 139 | Platelet factor 4 (B) | Hydrophobic |
Ligand interaction network
ZDO_C_1_IDS_C_2_SUS_C_3_BDP_C_4_SGN_C_5
Interaction pattern search
Search complexes with similar interaction patterns:
