Interactions for 4RAU (chain F)
Structure details
- PDB ID: 4RAU open_in_new
- Protein: CXCL4_HUMAN
- Organism: Homo sapiens
- UniProt ID: P02776 open_in_new
- Method: X-ray
- Resolution: 3.74 Å
- Date: March 16, 2016
- Reference: open_in_new
- State: monomer
Chemokine diagram
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Interactions found in structure
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Chemokine Residue | Generic number | Segment | Partner Residue | Partner | Interaction Type |
---|---|---|---|---|---|
Asp 5 | 58 | N-term | LYS 95 | RTOFab light chain (D) | Anionic |
Asp 7 | 60 | N-term | LYS 95 | RTOFab light chain (D) | Anionic |
Arg 20 | 76 | N-loop | ARG 20 | Platelet factor 4 (R) | VdWContact |
Pro 21 | 80 | N-loop | VAL 19 | Platelet factor 4 (R) | VdWContact |
Pro 21 | 80 | N-loop | PRO 21 | Platelet factor 4 (R) | Hydrophobic |
Pro 21 | 80 | N-loop | SER 17 | Platelet factor 4 (R) | VdWContact |
Arg 22 | 81 | N-loop | GLN 18 | Platelet factor 4 (R) | Hydrophobic |
Arg 22 | 81 | N-loop | GLN 18 | Platelet factor 4 (R) | VdWContact |
Lys 31 | 90 | 30s-loop | SER 55 | RTOFab heavy chain (E) | VdWContact |
Ala 32 | 91 | 30s-loop | TYR 106 | RTOFab heavy chain (E) | Hydrophobic |
Ala 32 | 91 | 30s-loop | TYR 106 | RTOFab heavy chain (E) | VdWContact |
Ala 32 | 91 | 30s-loop | LEU 103 | RTOFab heavy chain (E) | VdWContact |
Gly 33 | 92 | 30s-loop | TYR 106 | RTOFab heavy chain (E) | VdWContact |
Pro 34 | 93 | 30s-loop | TYR 61 | RTOFab heavy chain (E) | Hydrophobic |
Pro 34 | 93 | 30s-loop | LEU 96 | RTOFab light chain (D) | Hydrophobic |
Pro 34 | 93 | 30s-loop | TYR 98 | RTOFab light chain (D) | Hydrophobic |
Pro 34 | 93 | 30s-loop | TYR 98 | RTOFab light chain (D) | VdWContact |
His 35 | 94 | 30s-loop | TYR 61 | RTOFab heavy chain (E) | Hydrophobic |
Pro 37 | 96 | 30s-loop | TYR 106 | RTOFab heavy chain (E) | VdWContact |
Pro 37 | 96 | 30s-loop | PHE 93 | RTOFab light chain (D) | Hydrophobic |
Pro 37 | 96 | 30s-loop | PHE 93 | RTOFab light chain (D) | VdWContact |
Pro 37 | 96 | 30s-loop | TYR 34 | RTOFab light chain (D) | Hydrophobic |
Pro 37 | 96 | 30s-loop | TYR 34 | RTOFab light chain (D) | VdWContact |
Thr 38 | 97 | 30s-loop | LEU 104 | RTOFab heavy chain (E) | VdWContact |
Ala 39 | 99 | 30s-loop | LEU 104 | RTOFab heavy chain (E) | HBDonor |
Ala 39 | 99 | 30s-loop | LEU 104 | RTOFab heavy chain (E) | VdWContact |
Ala 39 | 99 | 30s-loop | LEU 103 | RTOFab heavy chain (E) | VdWContact |
Leu 55 | 120 | 50s-loop | LEU 104 | RTOFab heavy chain (E) | Hydrophobic |
Gln 56 | 121 | 50s-loop | TYR 105 | RTOFab heavy chain (E) | HBDonor |
Gln 56 | 121 | 50s-loop | TYR 105 | RTOFab heavy chain (E) | VdWContact |
Tyr 60 | 125 | Helix | LEU 104 | RTOFab heavy chain (E) | Hydrophobic |
Lys 62 | 127 | Helix | LYS 62 | Platelet factor 4 (R) | Hydrophobic |
Lys 62 | 127 | Helix | LYS 62 | Platelet factor 4 (R) | VdWContact |
Ile 63 | 128 | Helix | LEU 104 | RTOFab heavy chain (E) | Hydrophobic |
Lys 65 | 130 | Helix | LYS 66 | Platelet factor 4 (R) | VdWContact |
Lys 66 | 131 | Helix | LYS 61 | Platelet factor 4 (R) | VdWContact |
Leu 68 | 133 | Helix | LEU 103 | RTOFab heavy chain (E) | Hydrophobic |
Leu 68 | 133 | Helix | LEU 103 | RTOFab heavy chain (E) | VdWContact |