Interactions for 7S5A (chain A)
Structure details
- PDB ID: 7S5A open_in_new
- Protein: CCL8_HUMAN
- Organism: Homo sapiens
- UniProt ID: P80075 open_in_new
- Method: X-ray
- Resolution: 1.37 Å
- Date: Sept. 29, 2021
- Reference: 10.1073/PNAS.2122105119 open_in_new
- State: dimer
Chemokine diagram
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Interactions found in structure
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| Chemokine Residue | Generic number | Segment | Partner Residue | Partner | Interaction Type |
|---|---|---|---|---|---|
| Asp 3 | 55 | N-term | ILE 16 | C-C motif chemokine 8 (B) | Hydrophobic |
| Asp 3 | 55 | N-term | ILE 16 | C-C motif chemokine 8 (B) | VdWContact |
| Asp 3 | 55 | N-term | ARG 18 | C-C motif chemokine 8 (B) | HBAcceptor |
| Asp 3 | 55 | N-term | ARG 18 | C-C motif chemokine 8 (B) | Anionic |
| Asp 3 | 55 | N-term | ARG 18 | C-C motif chemokine 8 (B) | VdWContact |
| Val 5 | 57 | N-term | ASN 14 | C-C motif chemokine 8 (B) | Hydrophobic |
| Val 5 | 57 | N-term | ASN 14 | C-C motif chemokine 8 (B) | VdWContact |
| Ser 6 | 58 | N-term | CYS 52 | C-C motif chemokine 8 (B) | HBAcceptor |
| Ser 6 | 58 | N-term | CYS 52 | C-C motif chemokine 8 (B) | VdWContact |
| Ser 6 | 58 | N-term | VAL 15 | C-C motif chemokine 8 (B) | VdWContact |
| Ser 6 | 58 | N-term | ILE 16 | C-C motif chemokine 8 (B) | HBDonor |
| Ser 6 | 58 | N-term | ILE 16 | C-C motif chemokine 8 (B) | VdWContact |
| Pro 8 | 60 | N-term | ILE 42 | C-C motif chemokine 8 (B) | Hydrophobic |
| Pro 8 | 60 | N-term | GLU 50 | C-C motif chemokine 8 (B) | Hydrophobic |
| Pro 8 | 60 | N-term | THR 10 | C-C motif chemokine 8 (B) | Hydrophobic |
| Pro 8 | 60 | N-term | THR 10 | C-C motif chemokine 8 (B) | VdWContact |
| Ile 9 | 61 | N-term | CYS 11 | C-C motif chemokine 8 (B) | HBAcceptor |
| Ile 9 | 61 | N-term | CYS 11 | C-C motif chemokine 8 (B) | HBDonor |
| Ile 9 | 61 | N-term | CYS 11 | C-C motif chemokine 8 (B) | VdWContact |
| Ile 9 | 61 | N-term | PHE 13 | C-C motif chemokine 8 (B) | Hydrophobic |
| Thr 10 | 62 | N-term | PRO 8 | C-C motif chemokine 8 (B) | Hydrophobic |
| Thr 10 | 62 | N-term | PRO 8 | C-C motif chemokine 8 (B) | VdWContact |
| Thr 10 | 62 | N-term | THR 10 | C-C motif chemokine 8 (B) | HBAcceptor |
| Thr 10 | 62 | N-term | THR 10 | C-C motif chemokine 8 (B) | VdWContact |
| Cys 11 | 63 | CX | ILE 9 | C-C motif chemokine 8 (B) | HBAcceptor |
| Cys 11 | 63 | CX | ILE 9 | C-C motif chemokine 8 (B) | HBDonor |
| Cys 11 | 63 | CX | ILE 9 | C-C motif chemokine 8 (B) | VdWContact |
| Phe 13 | 68 | N-loop | GLN 35 | C-C motif chemokine 8 (B) | Hydrophobic |
| Phe 13 | 68 | N-loop | VAL 5 | C-C motif chemokine 8 (B) | Hydrophobic |
| Phe 13 | 68 | N-loop | ILE 9 | C-C motif chemokine 8 (B) | Hydrophobic |
| Asn 14 | 69 | N-loop | VAL 5 | C-C motif chemokine 8 (B) | Hydrophobic |
| Gln 35 | 94 | 30s-loop | PHE 13 | C-C motif chemokine 8 (B) | Hydrophobic |
| Ile 42 | 102 | B2 | PRO 8 | C-C motif chemokine 8 (B) | Hydrophobic |
| Glu 50 | 115 | B3 | PRO 8 | C-C motif chemokine 8 (B) | Hydrophobic |
| Cys 52 | 117 | B3 | SER 6 | C-C motif chemokine 8 (B) | HBDonor |
| Cys 52 | 117 | B3 | SER 6 | C-C motif chemokine 8 (B) | VdWContact |
Interaction pattern search
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