Interactions for 8HNK (chain L)
Structure details
- PDB ID: 8HNK open_in_new
- Protein: CXCL11_HUMAN
- Organism: Homo sapiens
- UniProt ID: O14625 open_in_new
- Method: Cryo-em
- Resolution: 3.01 Å
- Date: Nov. 29, 2023
- Reference: 10.1038/S41594-023-01175-5 open_in_new
- State: monomer
Chemokine diagram
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Interactions found in structure
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| Chemokine Residue | Generic number | Segment | Partner Residue | Partner | Interaction Type |
|---|---|---|---|---|---|
| Phe 1 | 55 | N-term | PHE 135 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | Hydrophobic |
| Phe 1 | 55 | N-term | PHE 135 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | PiStacking |
| Phe 1 | 55 | N-term | PHE 135 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | VdWContact |
| Phe 1 | 55 | N-term | TYR 308 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | VdWContact |
| Phe 1 | 55 | N-term | TRP 268 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | Hydrophobic |
| Phe 1 | 55 | N-term | GLN 219 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | VdWContact |
| Phe 1 | 55 | N-term | SER 304 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | VdWContact |
| Phe 1 | 55 | N-term | TYR 271 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | Hydrophobic |
| Phe 1 | 55 | N-term | TYR 271 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | VdWContact |
| Phe 1 | 55 | N-term | PHE 131 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | Hydrophobic |
| Phe 1 | 55 | N-term | PHE 131 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | PiStacking |
| Phe 1 | 55 | N-term | PHE 131 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | VdWContact |
| Pro 2 | 56 | N-term | TYR 308 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | VdWContact |
| Pro 2 | 56 | N-term | TRP 109 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | Hydrophobic |
| Met 3 | 57 | N-term | LEU 190 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | Hydrophobic |
| Met 3 | 57 | N-term | TRP 109 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | Hydrophobic |
| Met 3 | 57 | N-term | TRP 109 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | VdWContact |
| Met 3 | 57 | N-term | TYR 205 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | Hydrophobic |
| Met 3 | 57 | N-term | TYR 205 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | VdWContact |
| Met 3 | 57 | N-term | PHE 131 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | Hydrophobic |
| Met 3 | 57 | N-term | PHE 131 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | VdWContact |
| Phe 4 | 58 | N-term | ARG 216 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | Hydrophobic |
| Phe 4 | 58 | N-term | ARG 216 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | VdWContact |
| Phe 4 | 58 | N-term | GLN 219 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | VdWContact |
| Phe 4 | 58 | N-term | LEU 215 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | Hydrophobic |
| Phe 4 | 58 | N-term | ARG 212 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | Hydrophobic |
| Phe 4 | 58 | N-term | TYR 205 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | Hydrophobic |
| Lys 5 | 59 | N-term | GLN 204 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | VdWContact |
| Lys 5 | 59 | N-term | ASP 52 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | Cationic |
| Lys 5 | 59 | N-term | ASP 52 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | VdWContact |
| Arg 6 | 60 | N-term | ASP 282 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | Cationic |
| Arg 6 | 60 | N-term | ASP 282 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | VdWContact |
| Arg 6 | 60 | N-term | GLN 209 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | VdWContact |
| Arg 6 | 60 | N-term | ARG 212 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | VdWContact |
| Arg 8 | 62 | N-term | GLU 293 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | Cationic |
| Arg 8 | 62 | N-term | GLU 293 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | VdWContact |
| Arg 8 | 62 | N-term | ASP 278 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | Cationic |
| Arg 8 | 62 | N-term | ASP 297 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | Cationic |
| Leu 10 | 66 | CX | PRO 42 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | Hydrophobic |
| Leu 10 | 66 | CX | PRO 42 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | VdWContact |
| Ile 12 | 68 | N-loop | ARG 288 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | Hydrophobic |
| Ile 12 | 68 | N-loop | ARG 288 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | VdWContact |
| Ile 12 | 68 | N-loop | CYS 43 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | Hydrophobic |
| Met 30 | 89 | B1 | GLU 196 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | Hydrophobic |
| Met 30 | 89 | B1 | ARG 197 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | Hydrophobic |
| Met 30 | 89 | B1 | ARG 197 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | VdWContact |
| Asn 34 | 93 | 30s-loop | ASN 206 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | VdWContact |
| Asn 34 | 93 | 30s-loop | PRO 208 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | VdWContact |
| Asn 34 | 93 | 30s-loop | PHE 207 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | VdWContact |
| Asn 35 | 94 | 30s-loop | ARG 212 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | HBAcceptor |
| Asn 35 | 94 | 30s-loop | ARG 212 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | VdWContact |
| Cys 36 | 95 | 30s-loop | ARG 197 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | Anionic |
| Cys 36 | 95 | 30s-loop | ARG 197 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | VdWContact |
| Glu 40 | 100 | 30s-loop | ARG 197 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | Anionic |
| Glu 40 | 100 | 30s-loop | ARG 197 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | VdWContact |
| Ile 42 | 102 | B2 | PRO 42 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | Hydrophobic |
| Ile 42 | 102 | B2 | PRO 42 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | VdWContact |
| Gln 51 | 115 | B3 | PRO 42 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | VdWContact |
| Gln 51 | 115 | B3 | PRO 41 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | VdWContact |
| Arg 52 | 116 | B3 | SER 40 | Soluble cytochrome b562,C-X-C chemokine receptor type 3,Oplophorus-luciferin 2-monooxygenase catalytic subunit (R) | VdWContact |
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