Interactions

4R9Y | CXCL4_HUMAN — CXCL4

Residue contacts: 51
SUMMARY
Protein
CXCL4_HUMAN View protein entry
Organism
Homo sapiens
UniProt ID
P02776 View on UniProt
PDB ID
4R9Y View on PDB
Method
X-ray
Resolution
4.11 Å
Date
Dec. 16, 2015
Reference
10.1038/NCOMMS9277 Open DOI
State
Tetramer
Chain information
Chemokine chain
A
Partner chain
B,C,D
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INTERACTION TABLE
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Chemokine Residue Generic Number Segment Partner Residue Partner Chain Interaction Type
Asp 7 NTc.Cm3 N-term VAL 13 C VdWContact
Leu 8 NTc.Cm2 N-term LEU 11 C VdWContact
Leu 8 NTc.Cm2 N-term LYS 50 C VdWContact
Leu 8 NTc.Cm2 N-term CYS 12 C Hydrophobic
Leu 8 NTc.Cm2 N-term CYS 12 C VdWContact
Gln 9 NTc.Cm1 N-term LEU 11 C HBDonor
Gln 9 NTc.Cm1 N-term LEU 11 C VdWContact
Gln 9 NTc.Cm1 N-term GLN 9 C VdWContact
Cys 10 CX.1 CX GLN 9 C HBAcceptor
Leu 11 CX.4 CX LEU 11 C Hydrophobic
Leu 11 CX.4 CX LEU 11 C VdWContact
Leu 11 CX.4 CX GLN 9 C VdWContact
Leu 11 CX.4 CX LEU 8 C VdWContact
Val 13 cxb1.1 N-loop GLN 9 C Hydrophobic
Val 13 cxb1.1 N-loop GLN 9 C VdWContact
Val 13 cxb1.1 N-loop ASP 7 C Hydrophobic
Val 13 cxb1.1 N-loop ASP 7 C VdWContact
Lys 14 cxb1.2 N-loop ASP 7 C Hydrophobic
Lys 14 cxb1.2 N-loop ASP 7 C VdWContact
Ile 24 B1.2 B1 LYS 31 B VdWContact
Thr 25 B1.3 B1 LYS 31 B Hydrophobic
Thr 25 B1.3 B1 LYS 31 B VdWContact
Ser 26 B1.4 B1 ILE 30 B VdWContact
Ser 26 B1.4 B1 VAL 29 B VdWContact
Leu 27 B1.5 B1 LEU 27 B VdWContact
Glu 28 B1.6 B1 GLU 28 B Hydrophobic
Val 29 B1.7 B1 LEU 27 B HBAcceptor
Val 29 B1.7 B1 SER 26 B VdWContact
Val 29 B1.7 B1 THR 25 B VdWContact
Val 29 B1.7 B1 LEU 68 B Hydrophobic
Lys 31 b1b2.6 30s-loop LEU 67 B Hydrophobic
Lys 31 b1b2.6 30s-loop SER 70 B HBDonor
Lys 31 b1b2.6 30s-loop SER 70 B VdWContact
Lys 31 b1b2.6 30s-loop THR 25 B Hydrophobic
Lys 31 b1b2.6 30s-loop THR 25 B HBDonor
Lys 31 b1b2.6 30s-loop THR 25 B VdWContact
Lys 31 b1b2.6 30s-loop ILE 24 B VdWContact
Ala 39 b1b2.16 30s-loop LEU 68 B Hydrophobic
Asn 47 b2b3.4 40s-loop ASN 47 D VdWContact
Lys 50 B3.1 B3 LEU 8 C Hydrophobic
Lys 50 B3.1 B3 LEU 8 C VdWContact
Tyr 60 H.3 Helix LEU 68 B Hydrophobic
Tyr 60 H.3 Helix ILE 64 B Hydrophobic
Tyr 60 H.3 Helix ILE 64 B VdWContact
Ile 64 H.7 Helix TYR 60 B Hydrophobic
Ile 64 H.7 Helix TYR 60 B VdWContact
Leu 67 H.10 Helix LYS 31 B Hydrophobic
Leu 68 CT.1 C-term VAL 29 B Hydrophobic
Leu 68 CT.1 C-term TYR 60 B Hydrophobic
Ser 70 CT.3 C-term LYS 31 B HBAcceptor
Ser 70 CT.3 C-term LYS 31 B VdWContact
CHEMOKINE DIAGRAM
I K A G P H C P T A 30s-loop K N G R 40s-loop D L Q A 50s-loopC-term G D L Q C L C V K T T S Q V R P R N-term V E L S T I H Q L I A T L L C I K P L Y K K I I K K L L E S
INTERACTION PATTERN SEARCH
0.00 = no similarity, 1.00 = identical