Interactions

4R9Y | CXCL4_HUMAN — CXCL4

Residue contacts: 58
SUMMARY
Protein
CXCL4_HUMAN View protein entry
Organism
Homo sapiens
UniProt ID
P02776 View on UniProt
PDB ID
4R9Y View on PDB
Method
X-ray
Resolution
4.11 Å
Date
Dec. 16, 2015
Reference
10.1038/NCOMMS9277 Open DOI
State
Tetramer
Chain information
Chemokine chain
B
Partner chain
A,C,D
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INTERACTION TABLE
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Chemokine Residue Generic Number Segment Partner Residue Partner Chain Interaction Type
Asp 7 NTc.Cm3 N-term LYS 14 D Hydrophobic
Asp 7 NTc.Cm3 N-term LYS 14 D Anionic
Asp 7 NTc.Cm3 N-term LYS 14 D VdWContact
Asp 7 NTc.Cm3 N-term VAL 13 D VdWContact
Leu 8 NTc.Cm2 N-term CYS 52 D VdWContact
Gln 9 NTc.Cm1 N-term VAL 13 D Hydrophobic
Gln 9 NTc.Cm1 N-term LEU 11 D HBDonor
Gln 9 NTc.Cm1 N-term LEU 11 D VdWContact
Gln 9 NTc.Cm1 N-term GLN 9 D VdWContact
Cys 10 CX.1 CX GLN 9 D VdWContact
Leu 11 CX.4 CX LEU 8 D VdWContact
Leu 11 CX.4 CX LEU 11 D Hydrophobic
Leu 11 CX.4 CX LEU 11 D VdWContact
Leu 11 CX.4 CX GLN 9 D VdWContact
Val 13 cxb1.1 N-loop LEU 8 D VdWContact
Val 13 cxb1.1 N-loop ASP 7 D Hydrophobic
Val 13 cxb1.1 N-loop ASP 7 D VdWContact
Val 13 cxb1.1 N-loop GLN 9 D Hydrophobic
Val 13 cxb1.1 N-loop GLN 9 D VdWContact
Lys 14 cxb1.2 N-loop ASP 7 D Hydrophobic
Lys 14 cxb1.2 N-loop ASP 7 D VdWContact
Ile 24 B1.2 B1 LYS 31 A VdWContact
Thr 25 B1.3 B1 LYS 31 A Hydrophobic
Thr 25 B1.3 B1 LYS 31 A HBAcceptor
Thr 25 B1.3 B1 LYS 31 A VdWContact
Thr 25 B1.3 B1 VAL 29 A VdWContact
Ser 26 B1.4 B1 VAL 29 A VdWContact
Leu 27 B1.5 B1 VAL 29 A HBDonor
Leu 27 B1.5 B1 LEU 27 A VdWContact
Glu 28 B1.6 B1 GLU 28 A Hydrophobic
Val 29 B1.7 B1 SER 26 A VdWContact
Val 29 B1.7 B1 LEU 68 A Hydrophobic
Ile 30 b1b2.4 30s-loop SER 26 A VdWContact
Lys 31 b1b2.6 30s-loop SER 70 A HBDonor
Lys 31 b1b2.6 30s-loop SER 70 A VdWContact
Lys 31 b1b2.6 30s-loop ILE 24 A VdWContact
Lys 31 b1b2.6 30s-loop THR 25 A Hydrophobic
Lys 31 b1b2.6 30s-loop THR 25 A VdWContact
Lys 31 b1b2.6 30s-loop LEU 67 A Hydrophobic
Asn 47 b2b3.4 40s-loop GLY 48 C VdWContact
Asn 47 b2b3.4 40s-loop ASN 47 C VdWContact
Arg 49 b2b3.12 40s-loop LYS 46 C HBDonor
Arg 49 b2b3.12 40s-loop LYS 46 C VdWContact
Lys 50 B3.1 B3 LEU 8 D Hydrophobic
Lys 50 B3.1 B3 LEU 8 D VdWContact
Cys 52 B3.3 B3 ASP 7 D HBDonor
Cys 52 B3.3 B3 ASP 7 D VdWContact
Tyr 60 H.3 Helix ILE 64 A Hydrophobic
Tyr 60 H.3 Helix ILE 64 A VdWContact
Tyr 60 H.3 Helix LEU 68 A Hydrophobic
Ile 64 H.7 Helix TYR 60 A Hydrophobic
Ile 64 H.7 Helix TYR 60 A VdWContact
Leu 67 H.10 Helix LYS 31 A Hydrophobic
Leu 68 CT.1 C-term TYR 60 A Hydrophobic
Leu 68 CT.1 C-term VAL 29 A Hydrophobic
Leu 68 CT.1 C-term ALA 39 A Hydrophobic
Ser 70 CT.3 C-term LYS 31 A HBAcceptor
Ser 70 CT.3 C-term LYS 31 A VdWContact
CHEMOKINE DIAGRAM
I K A G P H C P T A 30s-loop K N G R 40s-loop D L Q A 50s-loopC-term G D L Q C L C V K T T S Q V R P R N-term V E L S T I H Q L I A T L L C I K P L Y K K I I K K L L E S
INTERACTION PATTERN SEARCH
0.00 = no similarity, 1.00 = identical