Interactions for 4LMQ — Binding Partner: hu30D8 Fab
Structure details
- PDB ID: 4LMQ open_in_new
- Protein: CXCL12_HUMAN
- Organism: Homo sapiens
- UniProt ID: P48061 open_in_new
- Method: X-ray
- Resolution: 2.77 Å
- Date: Aug. 14, 2013
- Reference: 10.1158/1078-0432.CCR-13-0943 open_in_new
- State: Dimer
- Chemokine Chain: F
- Partner Chain: I,E
Chemokine diagram
Interactions for this Binding Partner
Download list as CSV
| Chemokine Residue | Generic Number | Segment | Partner Residue | Partner Chain | Interaction Type |
|---|---|---|---|---|---|
| Glu 15 | cxb1.6 | N-loop | ASN 99 | E | HBAcceptor |
| Glu 15 | cxb1.6 | N-loop | ASN 99 | E | VdWContact |
| His 17 | cxb1.10 | N-loop | TYR 31 | I | Hydrophobic |
| His 17 | cxb1.10 | N-loop | TYR 31 | I | PiStacking |
| His 17 | cxb1.10 | N-loop | ASN 50 | I | HBAcceptor |
| His 17 | cxb1.10 | N-loop | ASN 50 | I | VdWContact |
| Val 18 | cxb1.11 | N-loop | ASN 99 | E | Hydrophobic |
| Val 18 | cxb1.11 | N-loop | ASN 99 | E | VdWContact |
| Ala 19 | cxb1.14 | N-loop | TYR 100 | E | HBDonor |
| Ala 19 | cxb1.14 | N-loop | TYR 100 | E | VdWContact |
| Ala 19 | cxb1.14 | N-loop | TYR 91 | I | Hydrophobic |
| Ala 19 | cxb1.14 | N-loop | TRP 92 | I | Hydrophobic |
| Ala 19 | cxb1.14 | N-loop | TRP 92 | I | VdWContact |
| Ala 19 | cxb1.14 | N-loop | SER 32 | I | VdWContact |
| Arg 20 | cxb1.15 | N-loop | TRP 92 | I | Hydrophobic |
| Arg 20 | cxb1.15 | N-loop | TRP 92 | I | VdWContact |
| Ala 21 | cxb1.16 | N-loop | PHE 96 | I | Hydrophobic |
| Ala 21 | cxb1.16 | N-loop | ASN 93 | I | VdWContact |
| Ala 21 | cxb1.16 | N-loop | TRP 92 | I | HBDonor |
| Ala 21 | cxb1.16 | N-loop | TRP 92 | I | VdWContact |
| Asn 22 | B1.1 | B1 | ASN 99 | E | HBDonor |
| Asn 22 | B1.1 | B1 | ASN 99 | E | VdWContact |
| Leu 42 | B2.6 | B2 | ASN 99 | E | Hydrophobic |
| Lys 43 | b2b3.2 | 40s-loop | GLU 58 | E | HBDonor |
| Lys 43 | b2b3.2 | 40s-loop | GLU 58 | E | Cationic |
| Lys 43 | b2b3.2 | 40s-loop | GLU 58 | E | VdWContact |
| Lys 43 | b2b3.2 | 40s-loop | TRP 52 | E | Hydrophobic |
| Lys 43 | b2b3.2 | 40s-loop | TRP 52 | E | VdWContact |
| Asn 44 | b2b3.3 | 40s-loop | LEU 98 | E | HBDonor |
| Asn 44 | b2b3.3 | 40s-loop | LEU 98 | E | VdWContact |
| Asn 44 | b2b3.3 | 40s-loop | ASP 95 | E | HBDonor |
| Asn 44 | b2b3.3 | 40s-loop | ASP 95 | E | VdWContact |
| Asn 44 | b2b3.3 | 40s-loop | SER 33 | E | HBAcceptor |
| Asn 44 | b2b3.3 | 40s-loop | SER 33 | E | VdWContact |
| Asn 44 | b2b3.3 | 40s-loop | TRP 52 | E | Hydrophobic |
| Asn 45 | b2b3.4 | 40s-loop | ASN 99 | E | HBDonor |
| Asn 45 | b2b3.4 | 40s-loop | ASN 99 | E | VdWContact |
| Asn 45 | b2b3.4 | 40s-loop | GLY 97 | E | HBDonor |
| Asn 45 | b2b3.4 | 40s-loop | GLY 97 | E | VdWContact |
| Arg 47 | b2b3.12 | 40s-loop | ASN 99 | E | HBDonor |
| Arg 47 | b2b3.12 | 40s-loop | ASN 99 | E | VdWContact |
| Trp 57 | H.2 | Helix | TRP 92 | I | Hydrophobic |
| Trp 57 | H.2 | Helix | TRP 92 | I | VdWContact |
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