Interactions

5EKI | CCL21_HUMAN — CCL21

Residue contacts: 61
SUMMARY
Protein
CCL21_HUMAN View protein entry
Organism
Homo sapiens
UniProt ID
O00585 View on UniProt
PDB ID
5EKI View on PDB
Method
X-ray
Resolution
1.9 Å
Date
Oct. 5, 2016
Reference
10.1021/ACS.BIOCHEM.6B00304 Open DOI
State
Oligomer
Chain information
Chemokine chain
E
Partner chain
B,D
3D VIEW
Powered by NGL viewer
INTERACTION TABLE
Download CSV
Chemokine Residue Generic Number Segment Partner Residue Partner Chain Interaction Type
Ala 5 NTc.Cm3 N-term LYS 75 D HBAcceptor
Ala 5 NTc.Cm3 N-term LYS 75 D VdWContact
Asp 7 NTc.Cm1 N-term LYS 75 D VdWContact
Asp 7 NTc.Cm1 N-term PRO 73 D Hydrophobic
Cys 8 CX.1 CX GLN 74 D HBAcceptor
Cys 8 CX.1 CX GLN 74 D HBDonor
Cys 8 CX.1 CX GLN 74 D VdWContact
Leu 10 cxb1.1 N-loop GLN 74 D Hydrophobic
Leu 10 cxb1.1 N-loop GLN 74 D VdWContact
Lys 11 cxb1.2 N-loop ASP 68 D Cationic
Lys 11 cxb1.2 N-loop ASP 68 D VdWContact
Lys 11 cxb1.2 N-loop PRO 71 D Hydrophobic
Ser 13 cxb1.6 N-loop LYS 69 D VdWContact
Ser 13 cxb1.6 N-loop PRO 71 D VdWContact
Gln 14 cxb1.7 N-loop LYS 69 D HBDonor
Gln 14 cxb1.7 N-loop LYS 69 D VdWContact
Arg 15 cxb1.8 N-loop THR 70 D Hydrophobic
Arg 23 B1.3 B1 ALA 49 B Hydrophobic
Arg 26 B1.6 B1 ASP 7 B HBDonor
Arg 26 B1.6 B1 ASP 7 B Cationic
Arg 26 B1.6 B1 ASP 7 B VdWContact
Gly 33 b1b2.10 30s-loop PRO 76 D VdWContact
Leu 40 B2.3 B2 PRO 73 D Hydrophobic
Arg 44 b2b3.2 40s-loop SER 47 B HBDonor
Arg 44 b2b3.2 40s-loop SER 47 B VdWContact
Arg 46 b2b3.9 40s-loop ARG 46 B HBDonor
Arg 46 b2b3.9 40s-loop ARG 46 B VdWContact
Arg 46 b2b3.9 40s-loop GLN 48 B HBDonor
Arg 46 b2b3.9 40s-loop GLN 48 B VdWContact
Ser 47 b2b3.10 40s-loop ARG 23 D VdWContact
Ala 49 b2b3.12 40s-loop ARG 23 D VdWContact
Glu 50 B3.1 B3 PRO 73 D Hydrophobic
Cys 52 B3.3 B3 PRO 71 D Hydrophobic
Cys 52 B3.3 B3 PRO 71 D HBDonor
Cys 52 B3.3 B3 PRO 71 D VdWContact
Asp 68 CT.1 C-term LYS 11 B Hydrophobic
Asp 68 CT.1 C-term LYS 11 B Anionic
Lys 69 CT.2 C-term GLN 14 B HBAcceptor
Lys 69 CT.2 C-term GLN 14 B VdWContact
Thr 70 CT.3 C-term LEU 51 B Hydrophobic
Thr 70 CT.3 C-term LEU 51 B VdWContact
Thr 70 CT.3 C-term ARG 15 B Hydrophobic
Thr 70 CT.3 C-term ARG 15 B VdWContact
Pro 71 CT.4 C-term LYS 11 B Hydrophobic
Pro 71 CT.4 C-term CYS 52 B Hydrophobic
Pro 71 CT.4 C-term CYS 52 B HBAcceptor
Pro 71 CT.4 C-term CYS 52 B VdWContact
Pro 71 CT.4 C-term LEU 51 B VdWContact
Pro 71 CT.4 C-term SER 13 B VdWContact
Ser 72 CT.5 C-term GLU 50 B VdWContact
Pro 73 CT.6 C-term LEU 40 B Hydrophobic
Pro 73 CT.6 C-term GLU 50 B Hydrophobic
Pro 73 CT.6 C-term ASP 7 B Hydrophobic
Gln 74 CT.7 C-term CYS 8 B HBAcceptor
Gln 74 CT.7 C-term CYS 8 B HBDonor
Gln 74 CT.7 C-term CYS 8 B VdWContact
Gln 74 CT.7 C-term LEU 10 B Hydrophobic
Gln 74 CT.7 C-term LEU 10 B VdWContact
Gln 74 CT.7 C-term ASP 7 B VdWContact
Ala 77 CT.10 C-term LEU 10 B Hydrophobic
Ala 77 CT.10 C-term GLY 33 B VdWContact
CHEMOKINE DIAGRAM
Q E P S L G C S I P 30s-loop R K R S Q A 40s-loop D P K E 50s-loopC-term A Q D C C L K Y S Q R K I P A K N-term K R Y S R V V A I L F L P A C L E L W V Q Q L M Q H L D K T P S P Q K P A
INTERACTION PATTERN SEARCH
0.00 = no similarity, 1.00 = identical