Interactions for 2VXW — Binding Partner: CCL5


Structure details


  • Chemokine Chain: C
  • Partner Chain: A,B,D

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Chemokine diagram


S G K C S N P A 30s-loop R K N R 40s-loop N P E K 50s-loopC-term Q S S A C C F A Y I A R P L P R A H N-term T Y F Y E K I V V F V T A C V Q K W V R E Y I N S L E M S
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Interactions for this Binding Partner


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Chemokine Residue Generic Number Segment Partner Residue Partner Chain Interaction Type
Phe 12 68 N-loop ALA 16 B HBAcceptor
Phe 12 68 N-loop ALA 16 B VdWContact
Ala 13 69 N-loop ALA 13 B Hydrophobic
Tyr 14 70 N-loop ALA 16 B Hydrophobic
Tyr 14 70 N-loop TYR 14 B HBAcceptor
Tyr 14 70 N-loop TYR 14 B HBDonor
Tyr 14 70 N-loop TYR 14 B VdWContact
Tyr 14 70 N-loop ALA 13 B VdWContact
Ile 15 71 N-loop PRO 2 A Hydrophobic
Ala 16 72 N-loop PHE 12 B HBDonor
Ala 16 72 N-loop PHE 12 B VdWContact
Ala 16 72 N-loop TYR 14 B Hydrophobic
Ala 16 72 N-loop ASN 36 B Hydrophobic
Arg 17 73 N-loop SER 35 B HBDonor
Arg 17 73 N-loop SER 35 B VdWContact
Arg 17 73 N-loop ASN 36 B VdWContact
Phe 28 87 B1 PHE 0 A Hydrophobic
Thr 30 89 B1 PHE 0 A Hydrophobic
Ser 35 96 30s-loop ARG 17 B VdWContact
Asn 36 97 30s-loop ARG 17 B VdWContact
Asn 36 97 30s-loop ALA 16 B Hydrophobic
Val 40 102 B2 PHE 0 A Hydrophobic
Arg 47 114 40s-loop SER 1 A HBDonor
Arg 47 114 40s-loop SER 1 A VdWContact
Gln 48 115 B3 PHE 0 A Hydrophobic
Gln 48 115 B3 PHE 0 A VdWContact
Gln 48 115 B3 SER 1 A HBAcceptor
Gln 48 115 B3 SER 1 A VdWContact
Val 49 116 B3 SER 1 A VdWContact
Cys 50 117 B3 PHE 0 A VdWContact
Cys 50 117 B3 SER 1 A HBDonor
Cys 50 117 B3 SER 1 A VdWContact
Glu 54 121 50s-loop LYS 55 B Anionic
Lys 55 122 50s-loop GLU 54 B Cationic

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