Interactions

8HNK | CXCL11_HUMAN — CXCR3

Residue contacts: 61
SUMMARY
Protein
CXCL11_HUMAN View protein entry
Organism
Homo sapiens
UniProt ID
O14625 View on UniProt
PDB ID
8HNK View on PDB
Method
Cryo-em
Resolution
3.01 Å
Date
Nov. 29, 2023
Reference
10.1038/S41594-023-01175-5 Open DOI
State
Monomer
Chain information
Chemokine chain
L
Partner chain
R
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INTERACTION TABLE
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Chemokine Residue Generic Number Segment Partner Residue Partner Chain Interaction Type
Phe 1 NTc.Cm8 N-term SER 304 R VdWContact
Phe 1 NTc.Cm8 N-term TYR 271 R Hydrophobic
Phe 1 NTc.Cm8 N-term TYR 271 R VdWContact
Phe 1 NTc.Cm8 N-term GLN 219 R VdWContact
Phe 1 NTc.Cm8 N-term PHE 135 R Hydrophobic
Phe 1 NTc.Cm8 N-term PHE 135 R PiStacking
Phe 1 NTc.Cm8 N-term PHE 135 R VdWContact
Phe 1 NTc.Cm8 N-term TYR 308 R VdWContact
Phe 1 NTc.Cm8 N-term PHE 131 R Hydrophobic
Phe 1 NTc.Cm8 N-term PHE 131 R PiStacking
Phe 1 NTc.Cm8 N-term PHE 131 R VdWContact
Phe 1 NTc.Cm8 N-term TRP 268 R Hydrophobic
Pro 2 NTc.Cm7 N-term TYR 308 R VdWContact
Pro 2 NTc.Cm7 N-term TRP 109 R Hydrophobic
Met 3 NTc.Cm6 N-term TYR 205 R Hydrophobic
Met 3 NTc.Cm6 N-term TYR 205 R VdWContact
Met 3 NTc.Cm6 N-term PHE 131 R Hydrophobic
Met 3 NTc.Cm6 N-term PHE 131 R VdWContact
Met 3 NTc.Cm6 N-term TRP 109 R Hydrophobic
Met 3 NTc.Cm6 N-term TRP 109 R VdWContact
Met 3 NTc.Cm6 N-term LEU 190 R Hydrophobic
Phe 4 NTc.Cm5 N-term LEU 215 R Hydrophobic
Phe 4 NTc.Cm5 N-term ARG 216 R Hydrophobic
Phe 4 NTc.Cm5 N-term ARG 216 R VdWContact
Phe 4 NTc.Cm5 N-term GLN 219 R VdWContact
Phe 4 NTc.Cm5 N-term TYR 205 R Hydrophobic
Phe 4 NTc.Cm5 N-term ARG 212 R Hydrophobic
Lys 5 NTc.Cm4 N-term GLN 204 R VdWContact
Lys 5 NTc.Cm4 N-term ASP 52 R Cationic
Lys 5 NTc.Cm4 N-term ASP 52 R VdWContact
Arg 6 NTc.Cm3 N-term ARG 212 R VdWContact
Arg 6 NTc.Cm3 N-term GLN 209 R VdWContact
Arg 6 NTc.Cm3 N-term ASP 282 R Cationic
Arg 6 NTc.Cm3 N-term ASP 282 R VdWContact
Arg 8 NTc.Cm1 N-term ASP 278 R Cationic
Arg 8 NTc.Cm1 N-term ASP 297 R Cationic
Arg 8 NTc.Cm1 N-term GLU 293 R Cationic
Arg 8 NTc.Cm1 N-term GLU 293 R VdWContact
Leu 10 CX.4 CX PRO 42 R Hydrophobic
Leu 10 CX.4 CX PRO 42 R VdWContact
Ile 12 cxb1.1 N-loop CYS 43 R Hydrophobic
Ile 12 cxb1.1 N-loop ARG 288 R Hydrophobic
Ile 12 cxb1.1 N-loop ARG 288 R VdWContact
Met 30 b1b2.4 30s-loop ARG 197 R Hydrophobic
Met 30 b1b2.4 30s-loop ARG 197 R VdWContact
Met 30 b1b2.4 30s-loop GLU 196 R Hydrophobic
Asn 34 b1b2.9 30s-loop PHE 207 R VdWContact
Asn 34 b1b2.9 30s-loop ASN 206 R VdWContact
Asn 34 b1b2.9 30s-loop PRO 208 R VdWContact
Asn 35 b1b2.10 30s-loop ARG 212 R HBAcceptor
Asn 35 b1b2.10 30s-loop ARG 212 R VdWContact
Cys 36 b1b2.12 30s-loop ARG 197 R HBAcceptor
Cys 36 b1b2.12 30s-loop ARG 197 R Anionic
Cys 36 b1b2.12 30s-loop ARG 197 R VdWContact
Glu 40 B2.1 B2 ARG 197 R Anionic
Glu 40 B2.1 B2 ARG 197 R VdWContact
Ile 42 B2.3 B2 PRO 42 R Hydrophobic
Ile 42 B2.3 B2 PRO 42 R VdWContact
Gln 51 B3.1 B3 PRO 41 R VdWContact
Gln 51 B3.1 B3 PRO 42 R VdWContact
Arg 52 B3.2 B3 SER 40 R VdWContact
CHEMOKINE DIAGRAM
M Y P S N N C D K I 30s-loop K E N K G 40s-loop N P K S 50s-loopC-term F P M F K R G R C L C I G P G V K A V K V A N-term I S A K E I D E V I I T L L C R Q K Q A R L I I K K V E R K N F
INTERACTION PATTERN SEARCH
0.00 = no similarity, 1.00 = identical