Interactions

8K4O | CXCL1_HUMAN — KSHV-GPCR

Residue contacts: 73
SUMMARY
Protein
CXCL1_HUMAN View protein entry
Organism
Homo sapiens
UniProt ID
P09341 View on UniProt
PDB ID
8K4O View on PDB
Method
Cryo-em
Resolution
3.01 Å
Date
July 24, 2024
Reference
-
State
Monomer
Chain information
Chemokine chain
F
Partner chain
E
3D VIEW
Powered by NGL viewer
INTERACTION TABLE
Download CSV
Chemokine Residue Generic Number Segment Partner Residue Partner Chain Interaction Type
Ala 1 NTc.Cm8 N-term TYR 125 E Hydrophobic
Ala 1 NTc.Cm8 N-term ILE 122 E Hydrophobic
Ser 2 NTc.Cm7 N-term ARG 183 E HBAcceptor
Ser 2 NTc.Cm7 N-term ARG 183 E VdWContact
Val 3 NTc.Cm6 N-term TYR 125 E Hydrophobic
Val 3 NTc.Cm6 N-term ILE 122 E Hydrophobic
Ala 4 NTc.Cm5 N-term ALA 297 E Hydrophobic
Ala 4 NTc.Cm5 N-term LEU 296 E Hydrophobic
Thr 5 NTc.Cm4 N-term TYR 197 E VdWContact
Glu 6 NTc.Cm3 N-term ARG 212 E Anionic
Glu 6 NTc.Cm3 N-term ARG 278 E VdWContact
Glu 6 NTc.Cm3 N-term ARG 208 E Anionic
Glu 6 NTc.Cm3 N-term ARG 208 E VdWContact
Glu 6 NTc.Cm3 N-term LEU 296 E VdWContact
Leu 7 NTc.Cm2 N-term ARG 278 E HBAcceptor
Leu 7 NTc.Cm2 N-term ARG 278 E VdWContact
Leu 7 NTc.Cm2 N-term MET 195 E Hydrophobic
Leu 7 NTc.Cm2 N-term TYR 197 E Hydrophobic
Arg 8 NTc.Cm1 N-term ASP 274 E HBDonor
Arg 8 NTc.Cm1 N-term ASP 274 E Cationic
Arg 8 NTc.Cm1 N-term ASP 274 E VdWContact
Arg 8 NTc.Cm1 N-term ASN 293 E HBDonor
Arg 8 NTc.Cm1 N-term ASN 293 E VdWContact
Cys 9 CX.1 CX ARG 289 E HBAcceptor
Cys 9 CX.1 CX ARG 289 E VdWContact
Gln 10 CX.4 CX SER 37 E VdWContact
Gln 10 CX.4 CX VAL 190 E VdWContact
Gln 10 CX.4 CX CYS 39 E HBAcceptor
Gln 10 CX.4 CX CYS 39 E VdWContact
Gln 10 CX.4 CX VAL 38 E Hydrophobic
Leu 12 cxb1.1 N-loop SER 37 E HBDonor
Leu 12 cxb1.1 N-loop SER 37 E VdWContact
Leu 12 cxb1.1 N-loop CYS 39 E Hydrophobic
Leu 12 cxb1.1 N-loop ASP 284 E Hydrophobic
Gln 13 cxb1.2 N-loop SER 37 E VdWContact
Leu 15 cxb1.6 N-loop PHE 32 E Hydrophobic
His 19 cxb1.14 N-loop TYR 28 E Hydrophobic
His 19 cxb1.14 N-loop TYR 28 E VdWContact
His 19 cxb1.14 N-loop PHE 32 E Hydrophobic
His 19 cxb1.14 N-loop PHE 32 E VdWContact
Lys 21 cxb1.16 N-loop ASP 13 E HBDonor
Lys 21 cxb1.16 N-loop ASP 13 E Cationic
Lys 21 cxb1.16 N-loop ASP 13 E VdWContact
Lys 21 cxb1.16 N-loop TRP 17 E Hydrophobic
Lys 21 cxb1.16 N-loop TRP 17 E VdWContact
Ile 23 B1.2 B1 LEU 11 E Hydrophobic
Asn 27 B1.6 B1 THR 8 E Hydrophobic
Asn 27 B1.6 B1 THR 8 E VdWContact
Val 28 B1.7 B1 THR 8 E HBAcceptor
Val 28 B1.7 B1 THR 8 E VdWContact
Val 28 B1.7 B1 LEU 7 E VdWContact
Val 28 B1.7 B1 PHE 6 E VdWContact
Pro 33 b1b2.9 30s-loop TYR 197 E Hydrophobic
Pro 33 b1b2.9 30s-loop THR 204 E Hydrophobic
Pro 33 b1b2.9 30s-loop THR 204 E VdWContact
Pro 33 b1b2.9 30s-loop ASN 199 E VdWContact
Pro 33 b1b2.9 30s-loop VAL 186 E Hydrophobic
His 34 b1b2.10 30s-loop PRO 189 E Hydrophobic
His 34 b1b2.10 30s-loop PRO 189 E VdWContact
Ile 41 B2.3 B2 VAL 38 E Hydrophobic
Ile 41 B2.3 B2 VAL 38 E VdWContact
Leu 44 B2.6 B2 PHE 32 E Hydrophobic
Arg 48 b2b3.12 40s-loop LEU 34 E VdWContact
Lys 49 B3.1 B3 GLU 40 E Cationic
Lys 49 B3.1 B3 VAL 38 E Hydrophobic
Lys 49 B3.1 B3 VAL 38 E VdWContact
Cys 51 B3.3 B3 VAL 38 E VdWContact
Lys 61 H.5 Helix TYR 26 E VdWContact
Ile 62 H.6 Helix TYR 26 E Hydrophobic
Ile 62 H.6 Helix TYR 26 E VdWContact
Ile 62 H.6 Helix GLU 19 E VdWContact
Ile 62 H.6 Helix LEU 21 E Hydrophobic
Ile 62 H.6 Helix LEU 21 E VdWContact
CHEMOKINE DIAGRAM
K S P G P H C A Q T 30s-loop K N G R 40s-loop N P A S 50s-loopC-term A S V A T E L R C Q C L Q T L Q G I H P K N-term V N V S Q I N E V I A T L L C A K P I V K K I I
INTERACTION PATTERN SEARCH
0.00 = no similarity, 1.00 = identical