Interactions

1PFM | CXCL4_HUMAN — CXCL4

Residue contacts: 50
SUMMARY
Protein
CXCL4_HUMAN View protein entry
Organism
Homo sapiens
UniProt ID
P02776 View on UniProt
PDB ID
1PFM View on PDB
Method
Nmr
Resolution
-
Date
Jan. 29, 1996
Reference
10.1021/BI00036A012 Open DOI
State
Tetramer
Chain information
Chemokine chain
C
Partner chain
A,B,D
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INTERACTION TABLE
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Chemokine Residue Generic Number Segment Partner Residue Partner Chain Interaction Type
Asp 7 NTc.Cm3 N-term GLN 18 A Hydrophobic
Asp 7 NTc.Cm3 N-term GLN 18 A HBAcceptor
Asp 7 NTc.Cm3 N-term GLN 18 A VdWContact
Gln 9 NTc.Cm1 N-term THR 16 A HBDonor
Gln 9 NTc.Cm1 N-term THR 16 A VdWContact
Gln 9 NTc.Cm1 N-term VAL 13 A VdWContact
Gln 9 NTc.Cm1 N-term CYS 12 A Cationic
Leu 11 CX.4 CX GLN 11 A Hydrophobic
Leu 11 CX.4 CX GLN 11 A VdWContact
Leu 11 CX.4 CX ARG 9 A HBAcceptor
Leu 11 CX.4 CX ARG 9 A VdWContact
Cys 12 CX.5 CX ARG 9 A VdWContact
Ser 26 B1.4 B1 VAL 29 D VdWContact
Ser 26 B1.4 B1 ILE 30 D VdWContact
Leu 27 B1.5 B1 VAL 29 D Hydrophobic
Leu 27 B1.5 B1 VAL 29 D HBAcceptor
Leu 27 B1.5 B1 VAL 29 D HBDonor
Leu 27 B1.5 B1 VAL 29 D VdWContact
Glu 28 B1.6 B1 LYS 50 A Anionic
Glu 28 B1.6 B1 GLU 28 D VdWContact
Val 29 B1.7 B1 LEU 67 D Hydrophobic
Val 29 B1.7 B1 LEU 27 D HBDonor
Val 29 B1.7 B1 LEU 27 D VdWContact
Ile 30 b1b2.4 30s-loop SER 26 D VdWContact
Lys 31 b1b2.6 30s-loop LEU 67 D Hydrophobic
Lys 31 b1b2.6 30s-loop LEU 67 D VdWContact
Lys 31 b1b2.6 30s-loop SER 70 D VdWContact
Pro 34 b1b2.9 30s-loop ARG 49 A VdWContact
Lys 46 b2b3.2 40s-loop GLY 48 B HBAcceptor
Lys 46 b2b3.2 40s-loop GLY 48 B VdWContact
Gly 48 b2b3.11 40s-loop LYS 46 B HBDonor
Gly 48 b2b3.11 40s-loop LYS 46 B VdWContact
Gly 48 b2b3.11 40s-loop THR 25 B HBAcceptor
Gly 48 b2b3.11 40s-loop THR 25 B VdWContact
Lys 50 B3.1 B3 GLN 11 A VdWContact
Leu 55 b3h.2 50s-loop LEU 67 D Hydrophobic
Leu 55 b3h.2 50s-loop LEU 68 D Hydrophobic
Tyr 60 H.3 Helix ILE 64 D Hydrophobic
Tyr 60 H.3 Helix LEU 68 D Hydrophobic
Tyr 60 H.3 Helix LEU 68 D VdWContact
Ile 64 H.7 Helix TYR 60 D Hydrophobic
Ile 64 H.7 Helix ILE 64 D Hydrophobic
Leu 67 H.10 Helix VAL 29 D Hydrophobic
Leu 67 H.10 Helix LYS 31 D Hydrophobic
Leu 67 H.10 Helix LYS 31 D VdWContact
Leu 68 CT.1 C-term TYR 60 D Hydrophobic
Leu 68 CT.1 C-term TYR 60 D VdWContact
Glu 69 CT.2 C-term LYS 31 D Anionic
Ser 70 CT.3 C-term LYS 31 D HBAcceptor
Ser 70 CT.3 C-term LYS 31 D VdWContact
CHEMOKINE DIAGRAM
I K A G P H C P T A 30s-loop K N G R 40s-loop D L Q A 50s-loopC-term M S A K E L R C Q C V K T T S Q V R P R N-term V E L S T I H Q L I A T L L C I K P L Y K K I I K K L L E S
INTERACTION PATTERN SEARCH
0.00 = no similarity, 1.00 = identical