Interactions for 1ICW — Binding Partner: CXCL8


Structure details

  • Chemokine Chain: A
  • Partner Chain: B
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Chemokine diagram

I E S G P H C A N T 30s-loop S D G R 40s-loop D P K E 50s-loopC-term E L R C Q C I K T Y S K P F H P K N-term V R L E K I F C I I V K L L A L E N W V Q R V V E K F L K R A E N S

Interactions for this Binding Partner

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Chemokine Residue Generic Number Segment Partner Residue Partner Chain Interaction Type
Lys 23 B1.3 B1 GLU 29 B Hydrophobic
Lys 23 B1.3 B1 GLU 29 B HBAcceptor
Lys 23 B1.3 B1 GLU 29 B VdWContact
Glu 24 B1.4 B1 VAL 27 B VdWContact
Glu 24 B1.4 B1 ILE 28 B Hydrophobic
Glu 24 B1.4 B1 ARG 26 B Anionic
Leu 25 B1.5 B1 VAL 27 B Hydrophobic
Leu 25 B1.5 B1 VAL 27 B HBAcceptor
Leu 25 B1.5 B1 VAL 27 B HBDonor
Leu 25 B1.5 B1 VAL 27 B VdWContact
Leu 25 B1.5 B1 ARG 26 B VdWContact
Arg 26 B1.6 B1 GLU 24 B HBDonor
Arg 26 B1.6 B1 GLU 24 B Cationic
Arg 26 B1.6 B1 GLU 24 B VdWContact
Arg 26 B1.6 B1 LEU 25 B VdWContact
Arg 26 B1.6 B1 ARG 26 B Hydrophobic
Arg 26 B1.6 B1 ARG 26 B VdWContact
Val 27 B1.7 B1 LEU 66 B Hydrophobic
Val 27 B1.7 B1 LEU 66 B VdWContact
Val 27 B1.7 B1 GLU 24 B VdWContact
Val 27 B1.7 B1 PHE 65 B Hydrophobic
Val 27 B1.7 B1 ALA 69 B Hydrophobic
Val 27 B1.7 B1 LEU 25 B Hydrophobic
Val 27 B1.7 B1 LEU 25 B HBAcceptor
Val 27 B1.7 B1 LEU 25 B HBDonor
Val 27 B1.7 B1 LEU 25 B VdWContact
Ile 28 b1b2.4 30s-loop GLU 24 B Hydrophobic
Ile 28 b1b2.4 30s-loop GLU 24 B VdWContact
Glu 29 b1b2.6 30s-loop LYS 23 B HBDonor
Glu 29 b1b2.6 30s-loop LYS 23 B VdWContact
Glu 29 b1b2.6 30s-loop PHE 65 B Hydrophobic
Glu 29 b1b2.6 30s-loop ALA 69 B Hydrophobic
Glu 29 b1b2.6 30s-loop ARG 68 B HBAcceptor
Glu 29 b1b2.6 30s-loop ARG 68 B Anionic
Glu 29 b1b2.6 30s-loop ARG 68 B VdWContact
Glu 29 b1b2.6 30s-loop SER 72 B HBAcceptor
Glu 29 b1b2.6 30s-loop SER 72 B VdWContact
Ser 30 b1b2.7 30s-loop SER 72 B HBDonor
Ser 30 b1b2.7 30s-loop SER 72 B VdWContact
Thr 37 b1b2.16 30s-loop ALA 69 B Hydrophobic
Thr 37 b1b2.16 30s-loop ALA 69 B HBDonor
Thr 37 b1b2.16 30s-loop ALA 69 B VdWContact
Lys 54 b3h.3 50s-loop ASN 71 B VdWContact
Lys 54 b3h.3 50s-loop GLU 70 B VdWContact
Gln 59 H.4 Helix GLU 70 B Hydrophobic
Gln 59 H.4 Helix GLU 70 B VdWContact
Val 62 H.7 Helix LEU 66 B Hydrophobic
Phe 65 H.10 Helix VAL 27 B Hydrophobic
Phe 65 H.10 Helix VAL 27 B VdWContact
Phe 65 H.10 Helix GLU 29 B Hydrophobic
Leu 66 CT.1 C-term VAL 62 B Hydrophobic
Leu 66 CT.1 C-term VAL 27 B Hydrophobic
Leu 66 CT.1 C-term LEU 66 B Hydrophobic
Lys 67 CT.2 C-term GLU 63 B Cationic
Arg 68 CT.3 C-term GLU 29 B HBDonor
Arg 68 CT.3 C-term GLU 29 B Cationic
Arg 68 CT.3 C-term GLU 29 B VdWContact
Ala 69 CT.4 C-term VAL 27 B Hydrophobic
Ala 69 CT.4 C-term THR 37 B Hydrophobic
Ala 69 CT.4 C-term THR 37 B VdWContact
Glu 70 CT.5 C-term GLN 59 B Hydrophobic
Glu 70 CT.5 C-term GLN 59 B VdWContact
Glu 70 CT.5 C-term PRO 53 B Hydrophobic
Glu 70 CT.5 C-term PRO 53 B VdWContact
Ser 72 CT.7 C-term LYS 54 B HBAcceptor
Ser 72 CT.7 C-term LYS 54 B VdWContact

Interaction pattern search
(0.00 = no similarity, 1.00 = identical)