Interactions for 8HNK — Binding Partner: CXCR3
Structure details
- PDB ID: 8HNK open_in_new
- Protein: CXCL11_HUMAN
- Organism: Homo sapiens
- UniProt ID: O14625 open_in_new
- Method: Cryo-em
- Resolution: 3.01 Å
- Date: Nov. 29, 2023
- Reference: 10.1038/S41594-023-01175-5 open_in_new
- State: Monomer
- Chemokine Chain: L
- Partner Chain: R
Chemokine diagram
Interactions for this Binding Partner
Download list as CSV
| Chemokine Residue | Generic Number | Segment | Partner Residue | Partner Chain | Interaction Type |
|---|---|---|---|---|---|
| Phe 1 | NTc.Cm8 | N-term | SER 304 | R | VdWContact |
| Phe 1 | NTc.Cm8 | N-term | TYR 271 | R | Hydrophobic |
| Phe 1 | NTc.Cm8 | N-term | TYR 271 | R | VdWContact |
| Phe 1 | NTc.Cm8 | N-term | GLN 219 | R | VdWContact |
| Phe 1 | NTc.Cm8 | N-term | PHE 135 | R | Hydrophobic |
| Phe 1 | NTc.Cm8 | N-term | PHE 135 | R | PiStacking |
| Phe 1 | NTc.Cm8 | N-term | PHE 135 | R | VdWContact |
| Phe 1 | NTc.Cm8 | N-term | TYR 308 | R | VdWContact |
| Phe 1 | NTc.Cm8 | N-term | PHE 131 | R | Hydrophobic |
| Phe 1 | NTc.Cm8 | N-term | PHE 131 | R | PiStacking |
| Phe 1 | NTc.Cm8 | N-term | PHE 131 | R | VdWContact |
| Phe 1 | NTc.Cm8 | N-term | TRP 268 | R | Hydrophobic |
| Pro 2 | NTc.Cm7 | N-term | TYR 308 | R | VdWContact |
| Pro 2 | NTc.Cm7 | N-term | TRP 109 | R | Hydrophobic |
| Met 3 | NTc.Cm6 | N-term | TYR 205 | R | Hydrophobic |
| Met 3 | NTc.Cm6 | N-term | TYR 205 | R | VdWContact |
| Met 3 | NTc.Cm6 | N-term | PHE 131 | R | Hydrophobic |
| Met 3 | NTc.Cm6 | N-term | PHE 131 | R | VdWContact |
| Met 3 | NTc.Cm6 | N-term | TRP 109 | R | Hydrophobic |
| Met 3 | NTc.Cm6 | N-term | TRP 109 | R | VdWContact |
| Met 3 | NTc.Cm6 | N-term | LEU 190 | R | Hydrophobic |
| Phe 4 | NTc.Cm5 | N-term | LEU 215 | R | Hydrophobic |
| Phe 4 | NTc.Cm5 | N-term | ARG 216 | R | Hydrophobic |
| Phe 4 | NTc.Cm5 | N-term | ARG 216 | R | VdWContact |
| Phe 4 | NTc.Cm5 | N-term | GLN 219 | R | VdWContact |
| Phe 4 | NTc.Cm5 | N-term | TYR 205 | R | Hydrophobic |
| Phe 4 | NTc.Cm5 | N-term | ARG 212 | R | Hydrophobic |
| Lys 5 | NTc.Cm4 | N-term | GLN 204 | R | VdWContact |
| Lys 5 | NTc.Cm4 | N-term | ASP 52 | R | Cationic |
| Lys 5 | NTc.Cm4 | N-term | ASP 52 | R | VdWContact |
| Arg 6 | NTc.Cm3 | N-term | ARG 212 | R | VdWContact |
| Arg 6 | NTc.Cm3 | N-term | GLN 209 | R | VdWContact |
| Arg 6 | NTc.Cm3 | N-term | ASP 282 | R | Cationic |
| Arg 6 | NTc.Cm3 | N-term | ASP 282 | R | VdWContact |
| Arg 8 | NTc.Cm1 | N-term | ASP 278 | R | Cationic |
| Arg 8 | NTc.Cm1 | N-term | ASP 297 | R | Cationic |
| Arg 8 | NTc.Cm1 | N-term | GLU 293 | R | Cationic |
| Arg 8 | NTc.Cm1 | N-term | GLU 293 | R | VdWContact |
| Leu 10 | CX.4 | CX | PRO 42 | R | Hydrophobic |
| Leu 10 | CX.4 | CX | PRO 42 | R | VdWContact |
| Ile 12 | cxb1.1 | N-loop | CYS 43 | R | Hydrophobic |
| Ile 12 | cxb1.1 | N-loop | ARG 288 | R | Hydrophobic |
| Ile 12 | cxb1.1 | N-loop | ARG 288 | R | VdWContact |
| Met 30 | b1b2.4 | 30s-loop | ARG 197 | R | Hydrophobic |
| Met 30 | b1b2.4 | 30s-loop | ARG 197 | R | VdWContact |
| Met 30 | b1b2.4 | 30s-loop | GLU 196 | R | Hydrophobic |
| Asn 34 | b1b2.9 | 30s-loop | PHE 207 | R | VdWContact |
| Asn 34 | b1b2.9 | 30s-loop | ASN 206 | R | VdWContact |
| Asn 34 | b1b2.9 | 30s-loop | PRO 208 | R | VdWContact |
| Asn 35 | b1b2.10 | 30s-loop | ARG 212 | R | HBAcceptor |
| Asn 35 | b1b2.10 | 30s-loop | ARG 212 | R | VdWContact |
| Cys 36 | b1b2.12 | 30s-loop | ARG 197 | R | HBAcceptor |
| Cys 36 | b1b2.12 | 30s-loop | ARG 197 | R | Anionic |
| Cys 36 | b1b2.12 | 30s-loop | ARG 197 | R | VdWContact |
| Glu 40 | B2.1 | B2 | ARG 197 | R | Anionic |
| Glu 40 | B2.1 | B2 | ARG 197 | R | VdWContact |
| Ile 42 | B2.3 | B2 | PRO 42 | R | Hydrophobic |
| Ile 42 | B2.3 | B2 | PRO 42 | R | VdWContact |
| Gln 51 | B3.1 | B3 | PRO 41 | R | VdWContact |
| Gln 51 | B3.1 | B3 | PRO 42 | R | VdWContact |
| Arg 52 | B3.2 | B3 | SER 40 | R | VdWContact |
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