Interactions

1RHP | CXCL4_HUMAN — CXCL4

Residue contacts: 93
SUMMARY
Protein
CXCL4_HUMAN View protein entry
Organism
Homo sapiens
UniProt ID
P02776 View on UniProt
PDB ID
1RHP View on PDB
Method
X-ray
Resolution
2.4 Å
Date
Nov. 30, 1994
Reference
10.1021/BI00193A025 Open DOI
State
Tetramer
Chain information
Chemokine chain
C
Partner chain
A,B,D
3D VIEW
Powered by NGL viewer
INTERACTION TABLE
Download CSV
Chemokine Residue Generic Number Segment Partner Residue Partner Chain Interaction Type
Asp 7 NTc.Cm3 N-term GLN 18 A VdWContact
Leu 8 NTc.Cm2 N-term GLN 18 A Hydrophobic
Leu 8 NTc.Cm2 N-term GLN 18 A VdWContact
Leu 8 NTc.Cm2 N-term ILE 51 A Hydrophobic
Leu 8 NTc.Cm2 N-term ILE 51 A VdWContact
Leu 8 NTc.Cm2 N-term THR 16 A Hydrophobic
Leu 8 NTc.Cm2 N-term THR 16 A VdWContact
Gln 9 NTc.Cm1 N-term ILE 51 A VdWContact
Gln 9 NTc.Cm1 N-term LYS 14 A Hydrophobic
Gln 9 NTc.Cm1 N-term LYS 14 A HBDonor
Gln 9 NTc.Cm1 N-term LYS 14 A VdWContact
Leu 11 CX.4 CX LYS 50 A Hydrophobic
Leu 11 CX.4 CX CYS 52 A Hydrophobic
Leu 11 CX.4 CX CYS 52 A VdWContact
Leu 11 CX.4 CX LEU 11 A Hydrophobic
Leu 11 CX.4 CX LEU 11 A VdWContact
Val 13 cxb1.1 N-loop VAL 13 A Hydrophobic
Lys 14 cxb1.2 N-loop VAL 13 A Hydrophobic
Lys 14 cxb1.2 N-loop GLN 9 A VdWContact
Thr 16 cxb1.6 N-loop GLN 9 A Hydrophobic
Thr 16 cxb1.6 N-loop GLN 9 A VdWContact
Thr 25 B1.3 B1 ILE 30 D VdWContact
Thr 25 B1.3 B1 LYS 31 D HBAcceptor
Thr 25 B1.3 B1 LYS 31 D VdWContact
Ser 26 B1.4 B1 VAL 29 D VdWContact
Leu 27 B1.5 B1 VAL 29 D HBAcceptor
Leu 27 B1.5 B1 VAL 29 D HBDonor
Leu 27 B1.5 B1 VAL 29 D VdWContact
Leu 27 B1.5 B1 GLU 28 D VdWContact
Glu 28 B1.6 B1 LYS 50 A HBAcceptor
Glu 28 B1.6 B1 LYS 50 A Anionic
Glu 28 B1.6 B1 LYS 50 A VdWContact
Glu 28 B1.6 B1 SER 26 D HBAcceptor
Glu 28 B1.6 B1 GLU 28 D Hydrophobic
Glu 28 B1.6 B1 GLU 28 D VdWContact
Val 29 B1.7 B1 SER 26 D VdWContact
Val 29 B1.7 B1 LEU 27 D HBAcceptor
Val 29 B1.7 B1 LEU 27 D HBDonor
Val 29 B1.7 B1 LEU 27 D VdWContact
Val 29 B1.7 B1 LEU 67 D Hydrophobic
Val 29 B1.7 B1 LEU 68 D Hydrophobic
Ile 30 b1b2.4 30s-loop LYS 50 A Hydrophobic
Ile 30 b1b2.4 30s-loop THR 25 D Hydrophobic
Ile 30 b1b2.4 30s-loop THR 25 D VdWContact
Ile 30 b1b2.4 30s-loop ARG 49 A VdWContact
Lys 31 b1b2.6 30s-loop THR 25 D HBDonor
Lys 31 b1b2.6 30s-loop THR 25 D VdWContact
Lys 31 b1b2.6 30s-loop ARG 49 A VdWContact
Lys 31 b1b2.6 30s-loop ARG 22 D VdWContact
Lys 31 b1b2.6 30s-loop LEU 67 D Hydrophobic
His 35 b1b2.10 30s-loop LEU 45 A Hydrophobic
His 35 b1b2.10 30s-loop ILE 51 A Hydrophobic
His 35 b1b2.10 30s-loop ARG 49 A Hydrophobic
His 35 b1b2.10 30s-loop ARG 49 A VdWContact
Ala 39 b1b2.16 30s-loop LEU 67 D VdWContact
Leu 41 B2.2 B2 LEU 68 D Hydrophobic
Leu 41 B2.2 B2 LEU 68 D VdWContact
Ile 42 B2.3 B2 LYS 50 A Hydrophobic
Ile 42 B2.3 B2 LYS 50 A VdWContact
Lys 46 b2b3.2 40s-loop LYS 31 D VdWContact
Asn 47 b2b3.4 40s-loop THR 25 B HBAcceptor
Asn 47 b2b3.4 40s-loop THR 25 B VdWContact
Arg 49 b2b3.12 40s-loop ILE 30 A Hydrophobic
Arg 49 b2b3.12 40s-loop ILE 30 A VdWContact
Arg 49 b2b3.12 40s-loop PRO 34 A VdWContact
Arg 49 b2b3.12 40s-loop HIS 35 A Hydrophobic
Lys 50 B3.1 B3 GLU 28 A Cationic
Lys 50 B3.1 B3 HIS 35 A VdWContact
Lys 50 B3.1 B3 LEU 11 A Hydrophobic
Lys 50 B3.1 B3 LEU 11 A VdWContact
Lys 50 B3.1 B3 ILE 42 A Hydrophobic
Lys 50 B3.1 B3 ILE 42 A VdWContact
Ile 51 B3.2 B3 GLN 9 A Hydrophobic
Ile 51 B3.2 B3 HIS 35 A Hydrophobic
Ile 51 B3.2 B3 HIS 35 A VdWContact
Cys 52 B3.3 B3 GLN 9 A VdWContact
Cys 52 B3.3 B3 LEU 11 A VdWContact
Leu 55 b3h.2 50s-loop LEU 68 D Hydrophobic
Leu 55 b3h.2 50s-loop LEU 68 D VdWContact
Tyr 60 H.3 Helix LEU 68 D Hydrophobic
Tyr 60 H.3 Helix LEU 68 D VdWContact
Ile 64 H.7 Helix ILE 64 D Hydrophobic
Ile 64 H.7 Helix ILE 64 D VdWContact
Leu 67 H.10 Helix VAL 29 D Hydrophobic
Leu 67 H.10 Helix LYS 31 D Hydrophobic
Leu 68 CT.1 C-term TYR 60 D Hydrophobic
Leu 68 CT.1 C-term TYR 60 D VdWContact
Leu 68 CT.1 C-term LEU 41 D Hydrophobic
Leu 68 CT.1 C-term LEU 41 D VdWContact
Leu 68 CT.1 C-term VAL 29 D Hydrophobic
Leu 68 CT.1 C-term LEU 55 D Hydrophobic
Leu 68 CT.1 C-term LEU 55 D VdWContact
Ser 70 CT.3 C-term LEU 55 D VdWContact
CHEMOKINE DIAGRAM
I K A G P H C P T A 30s-loop K N G R 40s-loop D L Q A 50s-loopC-term D L Q C L C V K T T S Q V R P R N-term V E L S T I H Q L I A T L L C I K P L Y K K I I K K L L E S
INTERACTION PATTERN SEARCH
0.00 = no similarity, 1.00 = identical