CXCL10_HUMAN

  • Alternate name(s): C-X-C motif chemokine 10, 10 kDa interferon gamma-induced protein, Gamma-IP10, IP-10, Small-inducible cytokine B10, CXCL10(1-73)
  • Organism: Homo sapiens
  • UniProt ID: P02778 open_in_new


Sequence

N-term   CX   N-loop   B1   30s-loop   B2   40s-loop   B3   50s-loop   Helix   C-term  
34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62   63 66 67   68 69 70 71 72 73 74 75 76 80 81 82   83 84 85 86 87 88 89   90 91 92 93 94 95 96 97 99 100   101 102 103 104 105   106 111 112 113 114   115 116 117 118   119 120 121 122   123 124 125 126 127 128 129 130 131 132 133 134 135   136 137 138 139 140 141  
M N Q T A I L I C C L I F L T L S G I Q G V P L S R T V R   C T C   I S I S N Q P V N P R S   L E K L E I I   P A S Q F C P R V E   I I A T M   K K K G E   K R C L   N P E S   K A I K N L L K A V S K E   R S K R S P  

Snake Plot

P A S Q F C P R V E 30s-loop K K K G E 40s-loop N P E S 50s-loopN-term M N Q T A I L I C C L I F L T L S G I Q G V P L S R T V R C T C I S I S N Q P V N P R S N-termC-term R S K R S P C-term I I E L K E L I I A T M L C R K K A I K N L L K A V S K E
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List of structures

PDB Method Resolution State Publication date Reference
1LV9 Solution nmr 0.0 monomer 2002-09-18 10.1021/BI026020Q open_in_new
1O7Y X-ray 3.0 tetramer 2003-05-08 10.1016/S0969-2126(03)00070-4 open_in_new
1O7Z X-ray 1.92 dimer 2003-05-08 10.1016/S0969-2126(03)00070-4 open_in_new
1O80 X-ray 2.0 dimer 2003-05-08 10.1016/S0969-2126(03)00070-4 open_in_new
8K2X Cryo-em 3.2 monomer 2023-11-29 10.1038/S41421-023-00617-0 open_in_new

Targets (Guide to Pharmacology)

No targets found