Protein
CXCL16_HUMAN
SUMMARY
- Gene
- CXCL16_HUMAN
- Full name
- C-X-C motif chemokine 16
- Organism
- Homo sapiens
- Subfamily
- CXCL
- Sequence type
- Wild-type
- UniProt ID
- Q9H2A7 Open UniProt
- IUPHAR ID
- 855 Open Guide to Pharmacology
- GtoP partners
- -
DIAGRAM
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SEQUENCE
Residues are colour-coded by structural context. Hover to view sequence and CCN numbering.
| N-term | |||||||||
|
M
|
G
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R
|
D
|
L
|
R
|
P
|
G
|
S
|
R
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| 10 | |||||||||
|
V
|
L
|
L
|
L
|
L
|
L
|
L
|
L
|
L
|
L
|
| 20 | |||||||||
|
V
|
Y
|
L
|
T
|
Q
|
P
|
G
|
N
|
G
|
N
|
| 30 | |||||||||
|
E
|
G
|
S
|
V
|
T
|
G
|
S
|
C
|
Y
|
C
|
| 40 | |||||||||
|
G
|
K
|
R
|
I
|
S
|
S
|
D
|
S
|
P
|
P
|
| 50 | |||||||||
| CX | N-loop | ||||||||
|
S
|
V
|
Q
|
F
|
M
|
N
|
R
|
L
|
R
|
K
|
| 60 | |||||||||
|
H
|
L
|
R
|
A
|
Y
|
H
|
R
|
C
|
L
|
Y
|
| 70 | |||||||||
| B1 | 30s-loop | ||||||||
|
Y
|
T
|
R
|
F
|
Q
|
L
|
L
|
S
|
W
|
S
|
| 80 | |||||||||
|
V
|
C
|
G
|
G
|
N
|
K
|
D
|
P
|
W
|
V
|
| 90 | |||||||||
| B2 | B3 | ||||||||
|
Q
|
E
|
L
|
M
|
S
|
C
|
L
|
D
|
L
|
K
|
| 100 | |||||||||
| 50s-loop | Helix | ||||||||
|
E
|
C
|
G
|
H
|
A
|
Y
|
S
|
G
|
I
|
V
|
| 110 | |||||||||
| C-term | |||||||||
|
A
|
H
|
Q
|
K
|
H
|
L
|
L
|
P
|
T
|
S
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| 120 | |||||||||
|
P
|
P
|
I
|
S
|
Q
|
A
|
S
|
E
|
G
|
A
|
| 130 | |||||||||
|
S
|
S
|
D
|
I
|
H
|
T
|
P
|
A
|
Q
|
M
|
| 140 | |||||||||
|
L
|
L
|
S
|
T
|
L
|
Q
|
S
|
T
|
Q
|
R
|
| 150 | |||||||||
|
P
|
T
|
L
|
P
|
V
|
G
|
S
|
L
|
S
|
S
|
| 160 | |||||||||
|
D
|
K
|
E
|
L
|
T
|
R
|
P
|
N
|
E
|
T
|
| 170 | |||||||||
|
T
|
I
|
H
|
T
|
A
|
G
|
H
|
S
|
L
|
A
|
| 180 | |||||||||
|
A
|
G
|
P
|
E
|
A
|
G
|
E
|
N
|
Q
|
K
|
| 190 | |||||||||
|
Q
|
P
|
E
|
K
|
N
|
A
|
G
|
P
|
T
|
A
|
| 200 | |||||||||
|
R
|
T
|
S
|
A
|
T
|
V
|
P
|
V
|
L
|
C
|
| 210 | |||||||||
|
L
|
L
|
A
|
I
|
I
|
F
|
I
|
L
|
T
|
A
|
| 220 | |||||||||
|
A
|
L
|
S
|
Y
|
V
|
L
|
C
|
K
|
R
|
R
|
| 230 | |||||||||
|
R
|
G
|
Q
|
S
|
P
|
Q
|
S
|
S
|
P
|
D
|
| 240 | |||||||||
|
L
|
P
|
V
|
H
|
Y
|
I
|
P
|
V
|
A
|
P
|
| 250 | |||||||||
|
D
|
S
|
N
|
T
|
| 254 | |||
STRUCTURES
No experimental structures available for this protein.
Predicted models and complexes
| Type | Partner | Method | State | Date | View |
|---|---|---|---|---|---|
| Complex | XCR1 | AlphaFold-Multimer | - | 2025-11-11 | Open |
| Complex | CXCR6 | AlphaFold-Multimer | - | 2025-11-11 | Open |
| Complex | CXCR5 | AlphaFold-Multimer | - | 2025-11-11 | Open |
| Complex | CXCR4 | AlphaFold-Multimer | - | 2025-11-11 | Open |
| Complex | CXCR3 | AlphaFold-Multimer | - | 2025-11-11 | Open |
| Complex | CXCR2 | AlphaFold-Multimer | - | 2025-11-11 | Open |
| Complex | CXCR1 | AlphaFold-Multimer | - | 2025-11-11 | Open |
| Complex | CX3CR1 | AlphaFold-Multimer | - | 2025-11-11 | Open |
| Complex | CCRL2 | AlphaFold-Multimer | - | 2025-11-11 | Open |
| Complex | CCR9 | AlphaFold-Multimer | - | 2025-11-11 | Open |
| Complex | CCR8 | AlphaFold-Multimer | - | 2025-11-11 | Open |
| Complex | CCR7 | AlphaFold-Multimer | - | 2025-11-11 | Open |
| Complex | CCR6 | AlphaFold-Multimer | - | 2025-11-11 | Open |
| Complex | CCR5 | AlphaFold-Multimer | - | 2025-11-11 | Open |
| Complex | CCR4 | AlphaFold-Multimer | - | 2025-11-11 | Open |
| Complex | CCR3 | AlphaFold-Multimer | - | 2025-11-10 | Open |
| Complex | CCR2 | AlphaFold-Multimer | - | 2025-11-10 | Open |
| Complex | CCR1 | AlphaFold-Multimer | - | 2025-11-10 | Open |
| Complex | CCR10 | AlphaFold-Multimer | - | 2025-11-10 | Open |
| Complex | ACKR4 | AlphaFold-Multimer | - | 2025-11-10 | Open |
| Complex | ACKR3 | AlphaFold-Multimer | - | 2025-11-10 | Open |
| Complex | ACKR2 | AlphaFold-Multimer | - | 2025-11-10 | Open |
| Complex | ACKR1 | AlphaFold-Multimer | - | 2025-11-10 | Open |
| Model | - | AlphaFold Monomer v2.0 pipeline (AlphaFold DB v6) | - | 2025-08-01 | Open |
SEQUENCE ALIGNMENT
Alignment requires at least one experimental structure.
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