XCL1_HUMAN

  • Alternate name(s): Lymphotactin
  • Organism: Homo sapiens
  • UniProt ID: P47992 open_in_new


Wild type sequence

Residue N-term   CX   N-loop   B1   30s-loop   B2   40s-loop   B3   50s-loop   Helix   C-term  
  32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62   67   68 69 70 71 72 73 74 75 76 80 81 82   83 84 85 86 87 88 89   90 91 96 97 99 100   101 102 103 104 105   106 112 113 114   115 116 117 118   119 120 121 122   123 124 125 126 127 128 129 130 131 132 133 134 135   136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162  
Wild Type M R L L I L A L L G I C S L T A Y I V E G V G S E V S D K R T   C   V S L T T Q R L P V S R   I K T Y T I T   E G S L R A   V I F I T   K R G L   K V C A   D P Q A   T W V R D V V R S M D R K   S N T R N N M I Q T K P T G T Q Q S T N T A V T L T G  

Snake Plot

E G S L R A 30s-loop K R G L 40s-loop D P Q A 50s-loopC-term M R L L I L A L L G I C S L T A Y I V E G V G S E V S D K R T C V S L T T Q R L P V S R N-term T I T Y T K I V I F I T A C V K T W V R D V V R S M D R K S N T R N N M I Q T K P T G T Q Q S T N T A V T L T G
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List of structures

PDB Method Resolution State Publication date Reference
1J8I - A Nmr None Monomer 2001-10-24 10.1021/BI011106P open_in_new
1J9O - A Nmr None Monomer 2001-10-24 10.1021/BI011106P open_in_new
2HDM - A Nmr None Monomer 2007-05-01 10.1021/BI602365D open_in_new
2JP1 - A,B Nmr None Dimer 2008-03-11 10.1073/PNAS.0709518105 open_in_new
2N54 - A,B Nmr None Dimer 2015-10-07 10.1021/ACSCHEMBIO.5B00542 open_in_new
2NYZ - E,D X-ray 2.6 Monomer 2007-12-25 10.1084/JEM.20071677 open_in_new
9AST - L Cryo-em 3.07 Monomer 2024-12-11 10.1073/PNAS.2405732121 open_in_new

Sequence alignment from structures

Generic Number 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 67 68 69 70 71 72 73 74 75 76 80 81 82 83 84 85 86 87 88 89 90 91 96 97 99 100 101 102 103 104 105 106 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162
Canonical Sequence M R L L I L A L L G I C S L T A Y I V E G V G S E V S D K R T C V S L T T Q R L P V S R I K T Y T I T E G S L R A V I F I T K R G L K V C A D P Q A T W V R D V V R S M D R K S N T R N N M I Q T K P T G T Q Q S T N T A V T L T G
 
1J8I - A - - - - - - - - - - - - - - - - - - - - - V G S E V S D K R T C V S L T T Q R L P V S R I K T Y T I T E G S L R A V I F I T K R G L K V C A D P Q A T W V R D V V R S M D R K S N T R N N M I Q T K P T G T Q Q S T N T A V T L T G
1J9O - A - - - - - - - - - - - - - - - - - - - - - V G S E V S D K R T C V S L T T Q R L P V S R I K T Y T I T E G S L R A V I F I T K R G L K V C A D P Q A T W V R D V V R S M D R K S N T R N N M I Q T K P T G T Q Q S T N T A V T L T G
2HDM - A - - - - - - - - - - - - - - - - - - - - - - G S E V S D K R T C V S L T T Q R L P C S R I K T Y T I T E G S L R A V I F I T K R G L K V C A D P Q A T W V R D C V R S M D R K S N T R N N M I Q - - - - - - - - - - - - - - - - - -
2JP1 - A,B - - - - - - - - - - - - - - - - - - - - - V G S E V S D K R T C V S L T T Q R L P V S R I K T Y T I T E G S L R A V I F I T K R G L K V C A D P Q A T W V R D V V - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
2N54 - A,B - - - - - - - - - - - - - - - - - - - - - V G S E V S D K R T C V S L T T Q R L P V S R I K T Y T I T E G S L R C V I F I T K R G L K V C C D P Q A T W V R D V V R S M D R K - - - - - - - - - - - - - - - - - - - - - - - - - - -
2NYZ - E,D - - - - - - - - - - - - - - - - - - - - - - - - - - - D K R T C V S L T T Q R L P V S R I K T Y T I T E G S L R A V I F I T K R G L K V C A D P Q A T W V R D V V R S M D R K S N T R N N - - - - - - - - - - - - - - - - - - - - -
9AST - L - - - - - - - - - - - - - - - - - - - - - V G S E V S D K R T C - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -