Structure 2X6G

Structure Details

PDB ID: 2X6G open_in_new
Protein: CCL3_HUMAN
Organism: Homo sapiens
UniProt ID: P10147 open_in_new

Method: X-ray
Resolution: 2.15 Å
Date: Nov. 3, 2010
Reference: 10.1038/EMBOJ.2010.256 open_in_new
State: Oligomer

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Chemokine-Partner Complexes

View complex: CCL3 (chain E) – CCL3 (chain C,D,F,G,H)

View complex: CCL3 (chain P) – CCL3 (chain M,N,O,Q,R)

View complex: CCL3 (chain O) – CCL3 (chain M,N,P,Q,R)

View complex: CCL3 (chain M) – CCL3 (chain K,L,N,O,P)

View complex: CCL3 (chain C) – CCL3 (chain A,B,D,E,F)

View complex: CCL3 (chain F) – CCL3 (chain C,D,E,G,H)

View complex: CCL3 (chain G) – CCL3 (chain E,F,H,I,J)

View complex: CCL3 (chain H) – CCL3 (chain E,F,G,I,J)

View complex: CCL3 (chain D) – CCL3 (chain A,B,C,E,F)

View complex: CCL3 (chain N) – CCL3 (chain K,L,M,O,P)

Segment	N-term																																CX		N-loop											B1							30s-loop								B2						40s-loop				B3				50s-loop				Helix										C-term
	NTc.Cm33	NTc.Cm32	NTc.Cm31	NTc.Cm30	NTc.Cm29	NTc.Cm28	NTc.Cm27	NTc.Cm26	NTc.Cm25	NTc.Cm24	NTc.Cm23	NTc.Cm22	NTc.Cm21	NTc.Cm20	NTc.Cm19	NTc.Cm18	NTc.Cm17	NTc.Cm16	NTc.Cm15	NTc.Cm14	NTc.Cm12	NTc.Cm11	NTc.Cm10	NTc.Cm9	NTc.Cm8	NTc.Cm7	NTc.Cm6	NTc.Cm5	NTc.Cm4	NTc.Cm3	NTc.Cm2	NTc.Cm1	CX.1	CX.5	cxb1.1	cxb1.2	cxb1.5	cxb1.6	cxb1.7	cxb1.8	cxb1.10	cxb1.11	cxb1.14	cxb1.15	cxb1.16	B1.1	B1.2	B1.3	B1.4	B1.5	B1.6	B1.7	b1b2.4	b1b2.6	b1b2.9	b1b2.10	b1b2.12	b1b2.13	b1b2.14	b1b2.16	B2.1	B2.2	B2.3	B2.4	B2.5	B2.6	b2b3.2	b2b3.4	b2b3.11	b2b3.12	B3.1	B3.2	B3.3	B3.4	b3h.1	b3h.2	b3h.3	b3h.4	H.1	H.2	H.3	H.4	H.5	H.6	H.7	H.8	H.9	H.10	CT.1	CT.2	CT.3	CT.4
UniProt Sequence	M	Q	V	S	T	A	A	L	A	V	L	L	C	T	M	A	L	C	N	Q	F	S	A	S	L	A	A	D	T	P	T	A	C	C	F	S	Y	T	S	R	Q	I	P	Q	N	F	I	A	D	Y	F	E	T	S	S	Q	C	S	K	P	G	V	I	F	L	T	K	R	S	R	Q	V	C	A	D	P	S	E	E	W	V	Q	K	Y	V	S	D	L	E	L	S	A
Structure (Chain I)	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	L	A	A	D	T	P	T	A	C	C	F	S	Y	T	S	R	Q	I	P	Q	N	F	I	A	A	Y	F	E	T	S	S	Q	C	S	K	P	G	V	I	F	L	T	K	R	S	R	Q	V	C	A	D	P	S	E	E	W	V	Q	K	Y	V	S	D	L	E	L	S	-
Structure (Chain H)	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	A	A	D	T	P	T	A	C	C	F	S	Y	T	S	R	Q	I	P	Q	N	F	I	A	A	Y	F	E	T	S	S	Q	C	S	K	P	G	V	I	F	L	T	K	R	S	R	Q	V	C	A	D	P	S	E	E	W	V	Q	K	Y	V	S	D	L	E	L	-	-
Structure (Chain E)	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	A	A	D	T	P	T	A	C	C	F	S	Y	T	S	R	Q	I	P	Q	N	F	I	A	A	Y	F	E	T	S	S	Q	C	S	K	P	G	V	I	F	L	T	K	R	S	R	Q	V	C	A	D	P	S	E	E	W	V	Q	K	Y	V	S	D	L	E	L	S	-
Structure (Chain Q)	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	A	A	D	T	P	T	A	C	C	F	S	Y	-	-	-	Q	I	P	Q	N	F	I	A	A	Y	F	E	T	S	S	Q	C	S	K	P	G	V	I	F	L	T	K	R	S	R	Q	V	C	A	D	P	S	E	E	W	V	Q	K	Y	V	S	D	L	E	L	S	-
Structure (Chain N)	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	A	D	T	P	T	A	C	C	F	S	Y	T	S	R	Q	I	P	Q	N	F	I	A	A	Y	F	E	T	S	S	Q	C	S	K	P	G	V	I	F	L	T	K	R	S	R	Q	V	C	A	D	P	S	E	E	W	V	Q	K	Y	V	S	D	L	E	L	S	-
Structure (Chain J)	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	A	D	T	P	T	A	C	C	F	S	Y	T	S	R	Q	I	P	Q	N	F	I	A	A	Y	F	E	T	S	S	Q	C	S	K	P	G	V	I	F	L	T	K	R	S	R	Q	V	C	A	D	P	S	E	E	W	V	Q	K	Y	V	S	D	L	E	L	S	-
Structure (Chain A)	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	A	D	T	P	T	A	C	C	F	S	Y	T	S	R	Q	I	P	Q	N	F	I	A	A	Y	F	E	T	S	S	Q	C	S	K	P	G	V	I	F	L	T	K	R	S	R	Q	V	C	A	D	P	S	E	E	W	V	Q	K	Y	V	S	D	L	E	L	S	A
Structure (Chain F)	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	A	D	T	P	T	A	C	C	F	S	Y	T	S	R	Q	I	P	Q	N	F	I	A	A	Y	F	E	T	S	S	Q	C	S	K	P	G	V	I	F	L	T	K	R	S	R	Q	V	C	A	D	P	S	E	E	W	V	Q	K	Y	V	S	D	L	E	L	S	A
Structure (Chain C)	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	A	D	T	P	T	A	C	C	F	S	Y	T	S	R	Q	I	P	Q	N	F	I	A	A	Y	F	E	T	S	S	Q	C	S	K	P	G	V	I	F	L	T	K	R	S	R	Q	V	C	A	D	P	S	E	E	W	V	Q	K	Y	V	S	D	L	E	L	S	-
Structure (Chain D)	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	A	D	T	P	T	A	C	C	F	S	Y	T	S	R	Q	I	P	Q	N	F	I	A	A	Y	F	E	T	S	S	Q	C	S	K	P	G	V	I	F	L	T	K	R	S	R	Q	V	C	A	D	P	S	E	E	W	V	Q	K	Y	V	S	D	L	E	L	S	-
Structure (Chain G)	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	A	D	T	P	T	A	C	C	F	S	Y	T	S	R	Q	I	P	Q	N	F	I	A	A	Y	F	E	T	S	S	Q	C	S	K	P	G	V	I	F	L	T	K	R	S	R	Q	V	C	-	D	P	S	E	E	W	V	Q	K	Y	V	S	D	L	E	L	-	-
Structure (Chain O)	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	A	D	T	P	T	A	C	C	F	S	Y	T	S	R	Q	I	P	Q	N	F	I	A	A	Y	F	E	T	S	S	Q	C	S	K	P	G	V	I	F	L	T	K	R	S	R	Q	V	C	A	D	P	S	E	E	W	V	Q	K	Y	V	S	D	L	E	L	S	-
Structure (Chain B)	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	A	D	T	P	T	A	C	C	F	S	Y	T	S	R	Q	I	P	Q	N	F	I	A	A	Y	F	E	T	S	S	Q	C	S	K	P	G	V	I	F	L	T	K	R	S	R	Q	V	C	A	D	P	S	E	E	W	V	Q	K	Y	V	S	D	L	E	L	S	-
Structure (Chain R)	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	D	T	P	T	A	C	C	F	S	Y	T	S	R	Q	I	P	Q	N	F	I	A	A	Y	F	E	T	S	S	Q	C	S	K	P	G	V	I	F	L	T	K	R	S	R	Q	V	C	A	D	P	S	E	E	W	V	Q	K	Y	V	S	D	L	E	L	-	-
Structure (Chain K)	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	D	T	P	T	A	C	C	F	S	Y	T	S	R	Q	I	P	Q	N	F	I	A	A	Y	F	E	T	S	S	Q	C	S	K	P	G	V	I	F	L	T	K	R	S	R	Q	V	C	A	D	P	S	E	E	W	V	Q	K	Y	V	S	D	L	-	-	-	-
Structure (Chain P)	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	D	T	P	T	A	C	C	F	S	Y	T	S	R	Q	I	P	Q	N	F	I	A	A	Y	F	E	T	S	S	Q	C	S	K	P	G	V	I	F	L	T	K	R	S	R	Q	V	C	A	D	P	S	E	E	W	V	Q	K	Y	V	S	D	L	E	L	S	-
Structure (Chain M)	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	T	P	T	A	C	C	F	S	Y	T	S	R	Q	I	P	Q	N	F	I	A	A	Y	F	E	T	S	S	Q	C	S	K	P	G	V	I	F	L	T	K	R	S	R	Q	V	C	A	D	P	S	E	E	W	V	Q	K	Y	V	S	D	L	E	L	-	-
Structure (Chain L)	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	P	T	A	C	C	F	S	Y	T	S	R	Q	I	P	Q	N	F	I	A	A	Y	F	E	T	S	S	Q	C	S	K	P	G	V	I	F	L	T	K	R	S	R	Q	V	C	A	D	P	S	E	E	W	V	Q	K	Y	V	S	D	L	E	L	S	-