Structure
5L2U | CCL5_HUMAN
SUMMARY
- PDB ID
- 5L2U Open RCSB entry
- Protein
- CCL5_HUMAN View protein entry
- Organism
- Homo sapiens
- UniProt ID
- P13501 Open UniProt
- Method
- X-ray
- Resolution
- 2.28 Å
- State
- Oligomer
- Publication
- -
- Release date
- 2017-08-09
3D VIEW
SEQUENCE ALIGNMENT
Comparison between the canonical chemokine sequence and residues observed in the experimental structure across canonical numbering positions.
| Segment | N-term | CX | N-loop | B1 | 30s-loop | B2 | 40s-loop | B3 | 50s-loop | Helix | C-term | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| NTc.Cm32 | NTc.Cm31 | NTc.Cm30 | NTc.Cm29 | NTc.Cm28 | NTc.Cm27 | NTc.Cm26 | NTc.Cm25 | NTc.Cm24 | NTc.Cm23 | NTc.Cm22 | NTc.Cm21 | NTc.Cm20 | NTc.Cm19 | NTc.Cm18 | NTc.Cm17 | NTc.Cm16 | NTc.Cm15 | NTc.Cm14 | NTc.Cm13 | NTc.Cm12 | NTc.Cm11 | NTc.Cm10 | NTc.Cm9 | NTc.Cm8 | NTc.Cm7 | NTc.Cm6 | NTc.Cm5 | NTc.Cm4 | NTc.Cm3 | NTc.Cm2 | NTc.Cm1 | CX.1 | CX.5 | cxb1.1 | cxb1.2 | cxb1.5 | cxb1.6 | cxb1.7 | cxb1.8 | cxb1.10 | cxb1.11 | cxb1.14 | cxb1.15 | cxb1.16 | B1.1 | B1.2 | B1.3 | B1.4 | B1.5 | B1.6 | B1.7 | b1b2.4 | b1b2.6 | b1b2.9 | b1b2.10 | b1b2.12 | b1b2.13 | b1b2.14 | b1b2.16 | B2.1 | B2.2 | B2.3 | B2.4 | B2.5 | B2.6 | b2b3.2 | b2b3.4 | b2b3.11 | b2b3.12 | B3.1 | B3.2 | B3.3 | B3.4 | b3h.1 | b3h.2 | b3h.3 | b3h.4 | H.1 | H.2 | H.3 | H.4 | H.5 | H.6 | H.7 | H.8 | H.9 | H.10 | CT.1 | CT.2 | CT.3 | ||||||||||||
| UniProt sequence | M | K | V | S | A | A | A | L | A | V | I | L | I | A | T | A | L | C | A | P | A | S | A | S | P | Y | S | S | D | T | T | P | C | C | F | A | Y | I | A | R | P | L | P | R | A | H | I | K | E | Y | F | Y | T | S | G | K | C | S | N | P | A | V | V | F | V | T | R | K | N | R | Q | V | C | A | N | P | E | K | K | W | V | R | E | Y | I | N | S | L | E | M | S | |||||||||||
| Structure (chain A) | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | S | S | D | T | T | P | C | C | F | A | Y | I | A | R | P | L | P | R | A | H | I | K | E | Y | F | Y | T | S | G | K | C | S | N | P | A | V | V | F | V | T | R | K | N | R | Q | V | C | A | N | P | E | K | K | W | V | R | E | Y | I | N | S | L | E | M | S | |||||||||||
| Structure (chain B) | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | S | S | D | T | T | P | C | C | F | A | Y | I | A | R | P | L | P | R | A | H | I | K | E | Y | F | Y | T | S | G | K | C | S | N | P | A | V | V | F | V | T | R | K | N | R | Q | V | C | A | N | P | E | K | K | W | V | R | E | Y | I | N | S | L | E | M | S | |||||||||||
| Structure (chain C) | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | S | S | D | T | T | P | C | C | F | A | Y | I | A | R | P | L | P | R | A | H | I | K | E | Y | F | Y | T | S | G | K | C | S | N | P | A | V | V | F | V | T | R | K | N | R | Q | V | C | A | N | P | E | K | K | W | V | R | E | Y | I | N | S | L | E | M | S | |||||||||||
| Structure (chain D) | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | S | D | T | T | P | C | C | F | A | Y | I | A | R | P | L | P | R | A | H | I | K | E | Y | F | Y | T | S | G | K | C | S | N | P | A | V | V | F | V | T | R | K | N | R | Q | V | C | A | N | P | E | K | K | W | V | R | E | Y | I | N | S | L | E | M | S | |||||||||||
| Structure (chain E) | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | S | S | D | T | T | P | C | C | F | A | Y | I | A | R | P | L | P | R | A | H | I | K | E | Y | F | Y | T | S | G | K | C | S | N | P | A | V | V | F | V | T | R | K | N | R | Q | V | C | A | N | P | E | K | K | W | V | R | E | Y | I | N | S | L | E | M | S | |||||||||||
| Structure (chain F) | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | S | D | T | T | P | C | C | F | A | Y | I | A | R | P | L | P | R | A | H | I | K | E | Y | F | Y | T | S | G | K | C | S | N | P | A | V | V | F | V | T | R | K | N | R | Q | V | C | A | N | P | E | K | K | W | V | R | E | Y | I | N | S | L | E | M | S | |||||||||||
| Structure (chain G) | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | S | D | T | T | P | C | C | F | A | Y | I | A | R | P | L | P | R | A | H | I | K | E | Y | F | Y | T | S | G | K | C | S | N | P | A | V | V | F | V | T | R | K | N | R | Q | V | C | A | N | P | E | K | K | W | V | R | E | Y | I | N | S | L | E | M | S | |||||||||||
| Structure (chain H) | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | S | D | T | T | P | C | C | F | A | Y | I | A | R | P | L | P | R | A | H | I | K | E | Y | F | Y | T | S | G | K | C | S | N | P | A | V | V | F | V | T | R | K | N | R | Q | V | C | A | N | P | E | K | K | W | V | R | E | Y | I | N | S | L | E | M | S | |||||||||||
| Structure (chain I) | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | S | S | D | T | T | P | C | C | F | A | Y | I | A | R | P | L | P | R | A | H | I | K | E | Y | F | Y | T | S | G | K | C | S | N | P | A | V | V | F | V | T | R | K | N | R | Q | V | C | A | N | P | E | K | K | W | V | R | E | Y | I | N | S | L | E | M | S | |||||||||||
Chemokine-partner complexes
Open a binding partner entry to explore residue-level interaction fingerprints.
CCL5 (chain C) -
CCL5 (chain F)
CCL5 (chain F) -
CCL5 (chain C)
CCL5 (chain C) -
CCL5 (chain D)
30 interactions
CCL5 (chain D) -
CCL5 (chain A)
CCL5 (chain F) -
CCL5 (chain D)
31 interactions
CCL5 (chain E) -
CCL5 (chain F)
33 interactions
CCL5 (chain A) -
CCL5 (chain B)
32 interactions
CCL5 (chain E) -
CCL5 (chain D)
6 interactions
CCL5 (chain D) -
CCL5 (chain F)
31 interactions
CCL5 (chain G) -
CCL5 (chain H)
30 interactions
CCL5 (chain I) -
CCL5 (chain H)
4 interactions
CCL5 (chain B) -
CCL5 (chain D)
29 interactions
CCL5 (chain C) -
CCL5 (chain E)
24 interactions
CCL5 (chain C) -
CCL5 (chain B)
6 interactions
CCL5 (chain D) -
CCL5 (chain C)
30 interactions
CCL5 (chain D) -
CCL5 (chain B)
29 interactions
CCL5 (chain G) -
CCL5 (chain I)
28 interactions
CCL5 (chain E) -
CCL5 (chain C)
24 interactions
CCL5 (chain A) -
CCL5 (chain C)
25 interactions
CCL5 (chain C) -
CCL5 (chain A)
25 interactions
CCL5 (chain A) -
CCL5 (chain D)
CCL5 (chain I) -
CCL5 (chain G)
28 interactions
CCL5 (chain H) -
CCL5 (chain G)
30 interactions
CCL5 (chain B) -
CCL5 (chain C)
6 interactions
CCL5 (chain B) -
CCL5 (chain A)
32 interactions
CCL5 (chain D) -
CCL5 (chain E)
6 interactions
CCL5 (chain F) -
CCL5 (chain E)
33 interactions
CCL5 (chain H) -
CCL5 (chain I)
4 interactions
