Predicted complex interactions
CCL23_HUMAN + ACKR3
SUMMARY
- Chemokine
- CCL23_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- ACKR3 View partner entry
- Partner description
- UniProt: P25106; Gene: ackr3_human; Family: Chemokine
- Interactions detected
- 144
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| PRO 20 | NTc.Cm51 | LYS 184 | - | VdWContact |
| PRO 20 | NTc.Cm51 | PHE 199 | - | Hydrophobic |
| PRO 20 | NTc.Cm51 | PHE 199 | - | VdWContact |
| VAL 21 | NTc.Cm50 | PHE 199 | - | VdWContact |
| VAL 21 | NTc.Cm50 | TYR 200 | - | VdWContact |
| VAL 21 | NTc.Cm50 | GLU 202 | - | Hydrophobic |
| VAL 21 | NTc.Cm50 | GLU 202 | - | VdWContact |
| VAL 21 | NTc.Cm50 | ILE 205 | 5.31x32 | Hydrophobic |
| LEU 22 | NTc.Cm49 | LYS 184 | - | Hydrophobic |
| LEU 22 | NTc.Cm49 | LYS 184 | - | VdWContact |
| LEU 22 | NTc.Cm49 | VAL 186 | - | Hydrophobic |
| LEU 22 | NTc.Cm49 | VAL 186 | - | VdWContact |
| LEU 22 | NTc.Cm49 | PHE 199 | - | Hydrophobic |
| LEU 22 | NTc.Cm49 | PHE 199 | - | VdWContact |
| LEU 23 | NTc.Cm48 | TYR 200 | - | Hydrophobic |
| LEU 23 | NTc.Cm48 | TYR 200 | - | VdWContact |
| LEU 23 | NTc.Cm48 | ILE 205 | 5.31x32 | Hydrophobic |
| LEU 23 | NTc.Cm48 | ILE 205 | 5.31x32 | VdWContact |
| LEU 23 | NTc.Cm48 | TRP 208 | 5.34x35 | Hydrophobic |
| LEU 23 | NTc.Cm48 | LEU 209 | 5.35x36 | Hydrophobic |
| LEU 23 | NTc.Cm48 | LEU 209 | 5.35x36 | VdWContact |
| ASP 24 | NTc.Cm47 | ARG 197 | 45.51x51 | Anionic |
| ASP 24 | NTc.Cm47 | ARG 197 | 45.51x51 | HBAcceptor |
| ASP 24 | NTc.Cm47 | ARG 197 | 45.51x51 | VdWContact |
| ARG 25 | NTc.Cm46 | ASP 179 | 4.60x61 | Cationic |
| ARG 25 | NTc.Cm46 | ASP 179 | 4.60x61 | HBDonor |
| ARG 25 | NTc.Cm46 | ASP 179 | 4.60x61 | VdWContact |
| ARG 25 | NTc.Cm46 | TYR 200 | - | VdWContact |
| ARG 25 | NTc.Cm46 | TRP 208 | 5.34x35 | HBDonor |
| ARG 25 | NTc.Cm46 | TRP 208 | 5.34x35 | VdWContact |
| ARG 25 | NTc.Cm46 | LEU 209 | 5.35x36 | Hydrophobic |
| ARG 25 | NTc.Cm46 | LEU 209 | 5.35x36 | VdWContact |
| ARG 25 | NTc.Cm46 | MET 212 | 5.38x39 | VdWContact |
| HIS 27 | NTc.Cm44 | GLU 290 | 7.28x27 | Hydrophobic |
| HIS 27 | NTc.Cm44 | GLU 290 | 7.28x27 | VdWContact |
| HIS 27 | NTc.Cm44 | LEU 293 | 7.31x30 | Hydrophobic |
| HIS 27 | NTc.Cm44 | PHE 294 | 7.32x31 | Hydrophobic |
| HIS 27 | NTc.Cm44 | PHE 294 | 7.32x31 | VdWContact |
| HIS 27 | NTc.Cm44 | LEU 297 | 7.35x34 | Hydrophobic |
| HIS 27 | NTc.Cm44 | LEU 297 | 7.35x34 | VdWContact |
| HIS 27 | NTc.Cm44 | HIS 298 | 7.36x35 | Hydrophobic |
| ALA 28 | NTc.Cm43 | ARG 197 | 45.51x51 | VdWContact |
| THR 29 | NTc.Cm42 | TYR 195 | - | HBDonor |
| THR 29 | NTc.Cm42 | TYR 195 | - | VdWContact |
| SER 30 | NTc.Cm41 | SER 188 | - | HBDonor |
| SER 30 | NTc.Cm41 | SER 188 | - | VdWContact |
| SER 30 | NTc.Cm41 | ASN 191 | - | VdWContact |
| SER 30 | NTc.Cm41 | GLU 193 | - | VdWContact |
| SER 30 | NTc.Cm41 | TYR 195 | - | VdWContact |
| ALA 31 | NTc.Cm40 | VAL 186 | - | Hydrophobic |
| ALA 31 | NTc.Cm40 | SER 188 | - | VdWContact |
| ASP 32 | NTc.Cm39 | SER 190 | - | HBAcceptor |
| ASP 32 | NTc.Cm39 | SER 190 | - | VdWContact |
| ILE 35 | NTc.Cm36 | PHE 199 | - | Hydrophobic |
| TYR 37 | NTc.Cm34 | ASP 30 | - | Hydrophobic |
| TYR 37 | NTc.Cm34 | ASP 30 | - | VdWContact |
| THR 38 | NTc.Cm33 | ASP 30 | - | HBDonor |
| THR 38 | NTc.Cm33 | ASP 30 | - | VdWContact |
| THR 38 | NTc.Cm33 | LYS 206 | 5.32x33 | HBAcceptor |
| THR 38 | NTc.Cm33 | LYS 206 | 5.32x33 | VdWContact |
| THR 38 | NTc.Cm33 | HIS 281 | 6.64x64 | Hydrophobic |
| THR 38 | NTc.Cm33 | HIS 281 | 6.64x64 | VdWContact |
| PRO 39 | NTc.Cm32 | VAL 28 | - | Hydrophobic |
| PRO 39 | NTc.Cm32 | VAL 28 | - | VdWContact |
| PRO 39 | NTc.Cm32 | ASP 30 | - | VdWContact |
| ARG 40 | NTc.Cm31 | PHE 14 | - | HBDonor |
| ARG 40 | NTc.Cm31 | PHE 14 | - | VdWContact |
| ARG 40 | NTc.Cm31 | VAL 28 | - | VdWContact |
| ARG 40 | NTc.Cm31 | VAL 29 | - | HBAcceptor |
| ARG 40 | NTc.Cm31 | VAL 29 | - | HBDonor |
| ARG 40 | NTc.Cm31 | VAL 29 | - | VdWContact |
| ARG 40 | NTc.Cm31 | HIS 281 | 6.64x64 | CationPi |
| ARG 40 | NTc.Cm31 | PHE 285 | - | VdWContact |
| SER 41 | NTc.Cm30 | TRP 19 | - | VdWContact |
| SER 41 | NTc.Cm30 | CYS 21 | - | VdWContact |
| SER 41 | NTc.Cm30 | CYS 26 | - | VdWContact |
| SER 41 | NTc.Cm30 | ILE 27 | - | VdWContact |
| ILE 42 | NTc.Cm29 | PHE 14 | - | Hydrophobic |
| ILE 42 | NTc.Cm29 | TRP 19 | - | Hydrophobic |
| ILE 42 | NTc.Cm29 | ILE 27 | - | HBAcceptor |
| ILE 42 | NTc.Cm29 | ILE 27 | - | HBDonor |
| ILE 42 | NTc.Cm29 | ILE 27 | - | VdWContact |
| ILE 42 | NTc.Cm29 | VAL 29 | - | Hydrophobic |
| ILE 42 | NTc.Cm29 | VAL 29 | - | VdWContact |
| PRO 43 | NTc.Cm28 | TRP 19 | - | Hydrophobic |
| PRO 43 | NTc.Cm28 | TRP 19 | - | VdWContact |
| PRO 43 | NTc.Cm28 | CYS 26 | - | VdWContact |
| CYS 44 | NTc.Cm27 | ASP 25 | - | HBDonor |
| CYS 44 | NTc.Cm27 | ASP 25 | - | VdWContact |
| LEU 46 | NTc.Cm25 | GLU 10 | - | VdWContact |
| LEU 46 | NTc.Cm25 | PHE 14 | - | Hydrophobic |
| LEU 46 | NTc.Cm25 | TRP 19 | - | Hydrophobic |
| LEU 46 | NTc.Cm25 | TRP 19 | - | VdWContact |
| LEU 47 | NTc.Cm24 | ILE 27 | - | Hydrophobic |
| LEU 47 | NTc.Cm24 | ILE 27 | - | VdWContact |
| ASN 54 | NTc.Cm17 | ALA 189 | - | Hydrophobic |
| ASN 54 | NTc.Cm17 | ALA 189 | - | VdWContact |
| LYS 59 | NTc.Cm12 | GLU 202 | - | Cationic |
| LYS 59 | NTc.Cm12 | GLU 202 | - | HBDonor |
| LYS 59 | NTc.Cm12 | GLU 202 | - | VdWContact |
| ILE 63 | NTc.Cm8 | MET 33 | - | Hydrophobic |
| PHE 64 | NTc.Cm7 | ILE 27 | - | Hydrophobic |
| PHE 64 | NTc.Cm7 | ILE 27 | - | VdWContact |
| PHE 64 | NTc.Cm7 | VAL 29 | - | Hydrophobic |
| LYS 68 | NTc.Cm3 | GLU 10 | - | Cationic |
| LYS 68 | NTc.Cm3 | GLU 10 | - | HBDonor |
| LYS 68 | NTc.Cm3 | GLU 10 | - | VdWContact |
| LYS 68 | NTc.Cm3 | PHE 14 | - | Hydrophobic |
| ARG 70 | NTc.Cm1 | GLY 12 | - | HBDonor |
| ARG 70 | NTc.Cm1 | GLY 12 | - | VdWContact |
| ARG 70 | NTc.Cm1 | PHE 14 | - | VdWContact |
| ARG 70 | NTc.Cm1 | VAL 32 | - | Hydrophobic |
| ARG 70 | NTc.Cm1 | MET 33 | - | VdWContact |
| ARG 70 | NTc.Cm1 | CYS 287 | 7.25x24 | Cationic |
| ARG 70 | NTc.Cm1 | CYS 287 | 7.25x24 | VdWContact |
| ARG 71 | CX.1 | MET 33 | - | HBAcceptor |
| ARG 71 | CX.1 | MET 33 | - | HBDonor |
| ARG 71 | CX.1 | MET 33 | - | Hydrophobic |
| ARG 71 | CX.1 | MET 33 | - | VdWContact |
| PHE 72 | CX.5 | PHE 14 | - | Hydrophobic |
| PHE 72 | CX.5 | VAL 29 | - | Hydrophobic |
| PHE 72 | CX.5 | VAL 29 | - | VdWContact |
| PHE 72 | CX.5 | THR 31 | - | VdWContact |
| PHE 72 | CX.5 | VAL 32 | - | Hydrophobic |
| PHE 72 | CX.5 | VAL 32 | - | VdWContact |
| CYS 73 | cxb1.1 | VAL 29 | - | VdWContact |
| CYS 73 | cxb1.1 | ASP 30 | - | HBAcceptor |
| CYS 73 | cxb1.1 | ASP 30 | - | VdWContact |
| CYS 73 | cxb1.1 | THR 31 | - | HBDonor |
| CYS 73 | cxb1.1 | THR 31 | - | VdWContact |
| ALA 74 | cxb1.2 | VAL 28 | - | VdWContact |
| ALA 74 | cxb1.2 | VAL 29 | - | Hydrophobic |
| ALA 74 | cxb1.2 | VAL 29 | - | VdWContact |
| ALA 74 | cxb1.2 | ASP 30 | - | VdWContact |
| GLN 80 | cxb1.11 | SER 23 | - | HBDonor |
| GLN 80 | cxb1.11 | SER 23 | - | VdWContact |
| GLN 80 | cxb1.11 | CYS 26 | - | VdWContact |
| GLN 80 | cxb1.11 | ILE 27 | - | Hydrophobic |
| GLN 80 | cxb1.11 | ILE 27 | - | VdWContact |
| VAL 81 | cxb1.14 | ILE 27 | - | Hydrophobic |
| VAL 81 | cxb1.14 | ILE 27 | - | VdWContact |
| CYS 84 | B1.1 | ILE 27 | - | Hydrophobic |
| CYS 84 | B1.1 | ILE 27 | - | VdWContact |
| MET 87 | B1.4 | ASP 25 | - | VdWContact |
