Predicted complex interactions
CCL25_HUMAN + ACKR3
SUMMARY
- Chemokine
- CCL25_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- ACKR3 View partner entry
- Partner description
- UniProt: P25106; Gene: ackr3_human; Family: Chemokine
- Interactions detected
- 159
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLN 1 | NTc.Cm29 | PHE 294 | 7.32x31 | Hydrophobic |
| GLN 1 | NTc.Cm29 | PHE 294 | 7.32x31 | VdWContact |
| GLN 1 | NTc.Cm29 | LEU 297 | 7.35x34 | VdWContact |
| GLN 1 | NTc.Cm29 | HIS 298 | 7.36x35 | Hydrophobic |
| GLN 1 | NTc.Cm29 | HIS 298 | 7.36x35 | VdWContact |
| VAL 3 | NTc.Cm27 | LYS 40 | - | VdWContact |
| VAL 3 | NTc.Cm27 | TYR 195 | - | Hydrophobic |
| VAL 3 | NTc.Cm27 | TYR 195 | - | VdWContact |
| VAL 3 | NTc.Cm27 | ARG 197 | 45.51x51 | HBAcceptor |
| VAL 3 | NTc.Cm27 | ARG 197 | 45.51x51 | VdWContact |
| PHE 4 | NTc.Cm26 | GLU 290 | 7.28x27 | Hydrophobic |
| PHE 4 | NTc.Cm26 | GLU 290 | 7.28x27 | VdWContact |
| PHE 4 | NTc.Cm26 | PHE 294 | 7.32x31 | Hydrophobic |
| PHE 4 | NTc.Cm26 | PHE 294 | 7.32x31 | VdWContact |
| GLU 5 | NTc.Cm25 | SER 188 | - | HBAcceptor |
| GLU 5 | NTc.Cm25 | SER 188 | - | VdWContact |
| GLU 5 | NTc.Cm25 | ASN 191 | - | HBAcceptor |
| GLU 5 | NTc.Cm25 | ASN 191 | - | VdWContact |
| GLU 5 | NTc.Cm25 | TYR 195 | - | Hydrophobic |
| ASP 6 | NTc.Cm24 | MET 33 | - | Hydrophobic |
| ASP 6 | NTc.Cm24 | MET 33 | - | VdWContact |
| HIS 12 | NTc.Cm18 | VAL 29 | - | HBDonor |
| HIS 12 | NTc.Cm18 | VAL 29 | - | Hydrophobic |
| HIS 12 | NTc.Cm18 | VAL 29 | - | VdWContact |
| HIS 12 | NTc.Cm18 | THR 31 | - | Hydrophobic |
| HIS 12 | NTc.Cm18 | THR 31 | - | VdWContact |
| ALA 18 | NTc.Cm12 | TRP 19 | - | Hydrophobic |
| ARG 22 | NTc.Cm8 | TRP 19 | - | CationPi |
| ARG 22 | NTc.Cm8 | TRP 19 | - | VdWContact |
| ARG 27 | NTc.Cm3 | SER 188 | - | HBDonor |
| ARG 27 | NTc.Cm3 | SER 188 | - | VdWContact |
| ARG 27 | NTc.Cm3 | SER 190 | - | HBDonor |
| ARG 27 | NTc.Cm3 | SER 190 | - | VdWContact |
| VAL 31 | CX.5 | PHE 199 | - | Hydrophobic |
| VAL 31 | CX.5 | PHE 199 | - | VdWContact |
| SER 32 | cxb1.1 | VAL 186 | - | VdWContact |
| SER 32 | cxb1.1 | ARG 197 | 45.51x51 | HBAcceptor |
| SER 32 | cxb1.1 | ARG 197 | 45.51x51 | VdWContact |
| GLY 33 | cxb1.2 | ARG 197 | 45.51x51 | VdWContact |
| GLY 33 | cxb1.2 | SER 198 | 45.52x52 | HBDonor |
| GLY 33 | cxb1.2 | SER 198 | 45.52x52 | VdWContact |
| CYS 35 | cxb1.7 | ARG 197 | 45.51x51 | Anionic |
| CYS 35 | cxb1.7 | ARG 197 | 45.51x51 | VdWContact |
| ASN 36 | cxb1.8 | ILE 205 | 5.31x32 | Hydrophobic |
| ASN 36 | cxb1.8 | ILE 205 | 5.31x32 | VdWContact |
| ASN 36 | cxb1.8 | LEU 209 | 5.35x36 | Hydrophobic |
| ASN 36 | cxb1.8 | LEU 209 | 5.35x36 | VdWContact |
| LEU 37 | cxb1.10 | ILE 205 | 5.31x32 | Hydrophobic |
| LEU 37 | cxb1.10 | ILE 205 | 5.31x32 | VdWContact |
| PRO 38 | cxb1.11 | GLU 202 | - | Hydrophobic |
| PRO 38 | cxb1.11 | GLU 202 | - | VdWContact |
| LYS 46 | B1.5 | PHE 14 | - | HBDonor |
| LYS 46 | B1.5 | PHE 14 | - | VdWContact |
| HIS 48 | B1.7 | MET 33 | - | Hydrophobic |
| HIS 48 | B1.7 | MET 33 | - | VdWContact |
| ARG 49 | b1b2.1 | ASP 30 | - | Cationic |
| ARG 49 | b1b2.1 | ASP 30 | - | HBDonor |
| ARG 49 | b1b2.1 | ASP 30 | - | VdWContact |
| ARG 49 | b1b2.1 | THR 31 | - | VdWContact |
| LYS 50 | b1b2.2 | THR 31 | - | VdWContact |
| LYS 50 | b1b2.2 | MET 33 | - | Hydrophobic |
| LYS 50 | b1b2.2 | MET 33 | - | VdWContact |
| VAL 51 | b1b2.3 | THR 31 | - | Hydrophobic |
| VAL 51 | b1b2.3 | THR 31 | - | VdWContact |
| LYS 56 | b1b2.9 | GLU 202 | - | Cationic |
| LYS 56 | b1b2.9 | GLU 202 | - | HBDonor |
| LYS 56 | b1b2.9 | GLU 202 | - | VdWContact |
| LEU 77 | b3h.1 | TYR 8 | - | Hydrophobic |
| PHE 84 | H.4 | LEU 5 | - | Hydrophobic |
| PHE 106 | CT.16 | GLN 106 | 2.66x66 | Hydrophobic |
| PHE 106 | CT.16 | GLN 106 | 2.66x66 | VdWContact |
| PHE 106 | CT.16 | HIS 107 | - | HBAcceptor |
| PHE 106 | CT.16 | HIS 107 | - | VdWContact |
| SER 107 | CT.17 | GLN 109 | 23.49x49 | HBAcceptor |
| SER 107 | CT.17 | GLN 109 | 23.49x49 | VdWContact |
| SER 107 | CT.17 | GLU 193 | - | HBDonor |
| SER 107 | CT.17 | GLU 193 | - | VdWContact |
| ASN 108 | CT.18 | LYS 40 | - | HBAcceptor |
| ASN 108 | CT.18 | LYS 40 | - | VdWContact |
| ASN 108 | CT.18 | SER 103 | 2.63x63 | HBDonor |
| ASN 108 | CT.18 | SER 103 | 2.63x63 | VdWContact |
| ASN 108 | CT.18 | GLN 106 | 2.66x66 | HBDonor |
| ASN 108 | CT.18 | GLN 106 | 2.66x66 | VdWContact |
| ASN 108 | CT.18 | HIS 107 | - | Hydrophobic |
| ASN 108 | CT.18 | HIS 107 | - | VdWContact |
| ASN 108 | CT.18 | ASN 108 | - | HBDonor |
| ASN 108 | CT.18 | ASN 108 | - | Hydrophobic |
| ASN 108 | CT.18 | ASN 108 | - | VdWContact |
| ASN 108 | CT.18 | GLN 109 | 23.49x49 | HBAcceptor |
| ASN 108 | CT.18 | GLN 109 | 23.49x49 | Hydrophobic |
| ASN 108 | CT.18 | GLN 109 | 23.49x49 | VdWContact |
| PRO 109 | CT.19 | ASN 108 | - | HBAcceptor |
| PRO 109 | CT.19 | ASN 108 | - | VdWContact |
| PRO 109 | CT.19 | GLN 109 | 23.49x49 | VdWContact |
| PRO 109 | CT.19 | TYR 195 | - | Hydrophobic |
| PRO 109 | CT.19 | TYR 195 | - | VdWContact |
| ILE 110 | CT.20 | TRP 100 | 2.60x60 | Hydrophobic |
| ILE 110 | CT.20 | TRP 100 | 2.60x60 | VdWContact |
| ILE 110 | CT.20 | SER 103 | 2.63x63 | VdWContact |
| ILE 110 | CT.20 | LEU 104 | 2.64x64 | Hydrophobic |
| ILE 110 | CT.20 | LEU 104 | 2.64x64 | VdWContact |
| ILE 110 | CT.20 | ASN 108 | - | HBDonor |
| ILE 110 | CT.20 | ASN 108 | - | Hydrophobic |
| ILE 110 | CT.20 | ASN 108 | - | VdWContact |
| ILE 110 | CT.20 | TRP 110 | 23.50x50 | Hydrophobic |
| SER 111 | CT.21 | HIS 298 | 7.36x35 | HBDonor |
| SER 111 | CT.21 | HIS 298 | 7.36x35 | VdWContact |
| SER 111 | CT.21 | GLN 301 | 7.39x38 | HBDonor |
| SER 111 | CT.21 | GLN 301 | 7.39x38 | VdWContact |
| SER 112 | CT.22 | GLN 301 | 7.39x38 | HBDonor |
| SER 112 | CT.22 | GLN 301 | 7.39x38 | VdWContact |
| SER 113 | CT.23 | ASP 275 | 6.58x58 | HBDonor |
| SER 113 | CT.23 | ASP 275 | 6.58x58 | VdWContact |
| SER 113 | CT.23 | LEU 297 | 7.35x34 | VdWContact |
| LYS 114 | CT.24 | ASP 179 | 4.60x61 | Cationic |
| LYS 114 | CT.24 | ASP 179 | 4.60x61 | HBDonor |
| LYS 114 | CT.24 | ASP 179 | 4.60x61 | VdWContact |
| LYS 114 | CT.24 | LEU 209 | 5.35x36 | Hydrophobic |
| LYS 114 | CT.24 | LEU 209 | 5.35x36 | VdWContact |
| LYS 114 | CT.24 | MET 212 | 5.38x39 | HBDonor |
| LYS 114 | CT.24 | MET 212 | 5.38x39 | VdWContact |
| LYS 114 | CT.24 | GLU 213 | 5.39x40 | Hydrophobic |
| LYS 114 | CT.24 | GLU 213 | 5.39x40 | VdWContact |
| LYS 114 | CT.24 | ASP 275 | 6.58x58 | HBDonor |
| LYS 114 | CT.24 | ASP 275 | 6.58x58 | VdWContact |
| ARG 115 | CT.25 | LEU 209 | 5.35x36 | VdWContact |
| ARG 115 | CT.25 | GLU 213 | 5.39x40 | VdWContact |
| ARG 115 | CT.25 | LEU 274 | 6.57x57 | HBDonor |
| ARG 115 | CT.25 | LEU 274 | 6.57x57 | VdWContact |
| ARG 115 | CT.25 | ASP 275 | 6.58x58 | Cationic |
| ARG 115 | CT.25 | ASP 275 | 6.58x58 | HBDonor |
| ARG 115 | CT.25 | ASP 275 | 6.58x58 | Hydrophobic |
| ARG 115 | CT.25 | ASP 275 | 6.58x58 | VdWContact |
| ARG 115 | CT.25 | ILE 276 | 6.59x59 | HBDonor |
| ARG 115 | CT.25 | ILE 276 | 6.59x59 | VdWContact |
| ARG 115 | CT.25 | PHE 277 | 6.60x60 | VdWContact |
| ARG 115 | CT.25 | SER 278 | 6.61x61 | VdWContact |
| ARG 115 | CT.25 | ILE 279 | 6.62x62 | Hydrophobic |
| ARG 115 | CT.25 | ILE 279 | 6.62x62 | VdWContact |
| ARG 115 | CT.25 | LEU 293 | 7.31x30 | VdWContact |
| ASN 116 | CT.26 | GLU 290 | 7.28x27 | HBDonor |
| ASN 116 | CT.26 | GLU 290 | 7.28x27 | VdWContact |
| VAL 117 | CT.27 | LYS 206 | 5.32x33 | Hydrophobic |
| VAL 117 | CT.27 | LYS 206 | 5.32x33 | VdWContact |
| VAL 117 | CT.27 | LEU 209 | 5.35x36 | Hydrophobic |
| VAL 117 | CT.27 | LEU 209 | 5.35x36 | VdWContact |
| VAL 117 | CT.27 | ILE 279 | 6.62x62 | Hydrophobic |
| VAL 117 | CT.27 | ILE 279 | 6.62x62 | VdWContact |
| VAL 117 | CT.27 | HIS 281 | 6.64x64 | HBAcceptor |
| VAL 117 | CT.27 | HIS 281 | 6.64x64 | VdWContact |
| SER 118 | CT.28 | LYS 206 | 5.32x33 | HBAcceptor |
| SER 118 | CT.28 | LYS 206 | 5.32x33 | VdWContact |
| SER 118 | CT.28 | HIS 281 | 6.64x64 | VdWContact |
| LEU 119 | CT.29 | LEU 280 | 6.63x63 | VdWContact |
| LEU 119 | CT.29 | HIS 281 | 6.64x64 | Hydrophobic |
| LEU 119 | CT.29 | HIS 281 | 6.64x64 | VdWContact |
| LEU 120 | CT.30 | LYS 206 | 5.32x33 | Hydrophobic |
| LEU 120 | CT.30 | LYS 206 | 5.32x33 | VdWContact |
| ALA 123 | CT.33 | ILE 27 | - | Hydrophobic |
