Predicted complex interactions
CCL27_HUMAN + ACKR3
SUMMARY
- Chemokine
- CCL27_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- ACKR3 View partner entry
- Partner description
- UniProt: P25106; Gene: ackr3_human; Family: Chemokine
- Interactions detected
- 81
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| PHE 1 | NTc.Cm32 | PHE 124 | 3.32x32 | Hydrophobic |
| PHE 1 | NTc.Cm32 | PHE 124 | 3.32x32 | PiStacking |
| PHE 1 | NTc.Cm32 | PHE 124 | 3.32x32 | VdWContact |
| PHE 1 | NTc.Cm32 | LEU 128 | 3.36x36 | Hydrophobic |
| PHE 1 | NTc.Cm32 | ASP 179 | 4.60x61 | Cationic |
| PHE 1 | NTc.Cm32 | ASP 179 | 4.60x61 | HBDonor |
| PHE 1 | NTc.Cm32 | ASP 179 | 4.60x61 | VdWContact |
| PHE 1 | NTc.Cm32 | TYR 268 | 6.51x51 | Hydrophobic |
| PHE 1 | NTc.Cm32 | TYR 268 | 6.51x51 | VdWContact |
| PHE 1 | NTc.Cm32 | GLN 301 | 7.39x38 | Hydrophobic |
| PHE 1 | NTc.Cm32 | GLN 301 | 7.39x38 | VdWContact |
| LEU 2 | NTc.Cm31 | ASP 179 | 4.60x61 | VdWContact |
| LEU 2 | NTc.Cm31 | LEU 209 | 5.35x36 | Hydrophobic |
| LEU 2 | NTc.Cm31 | MET 212 | 5.38x39 | Hydrophobic |
| LEU 2 | NTc.Cm31 | GLU 213 | 5.39x40 | Hydrophobic |
| LEU 2 | NTc.Cm31 | GLU 213 | 5.39x40 | VdWContact |
| LEU 3 | NTc.Cm30 | TRP 100 | 2.60x60 | Hydrophobic |
| LEU 3 | NTc.Cm30 | HIS 298 | 7.36x35 | Hydrophobic |
| PRO 4 | NTc.Cm29 | PHE 294 | 7.32x31 | Hydrophobic |
| PRO 4 | NTc.Cm29 | PHE 294 | 7.32x31 | VdWContact |
| PRO 4 | NTc.Cm29 | LEU 297 | 7.35x34 | Hydrophobic |
| PRO 4 | NTc.Cm29 | HIS 298 | 7.36x35 | Hydrophobic |
| PRO 5 | NTc.Cm28 | ARG 197 | 45.51x51 | HBAcceptor |
| PRO 5 | NTc.Cm28 | ARG 197 | 45.51x51 | VdWContact |
| SER 6 | NTc.Cm27 | ARG 197 | 45.51x51 | HBAcceptor |
| SER 6 | NTc.Cm27 | ARG 197 | 45.51x51 | VdWContact |
| THR 7 | NTc.Cm26 | TYR 195 | - | Hydrophobic |
| THR 7 | NTc.Cm26 | TYR 195 | - | VdWContact |
| THR 7 | NTc.Cm26 | ARG 197 | 45.51x51 | HBAcceptor |
| THR 7 | NTc.Cm26 | ARG 197 | 45.51x51 | VdWContact |
| ALA 8 | NTc.Cm25 | MET 33 | - | Hydrophobic |
| ALA 8 | NTc.Cm25 | MET 33 | - | VdWContact |
| GLN 12 | NTc.Cm21 | ASP 30 | - | HBDonor |
| GLN 12 | NTc.Cm21 | ASP 30 | - | Hydrophobic |
| GLN 12 | NTc.Cm21 | ASP 30 | - | VdWContact |
| GLN 12 | NTc.Cm21 | THR 31 | - | Hydrophobic |
| GLN 12 | NTc.Cm21 | THR 31 | - | VdWContact |
| GLN 12 | NTc.Cm21 | LYS 206 | 5.32x33 | VdWContact |
| TYR 14 | NTc.Cm19 | SER 24 | - | VdWContact |
| TYR 14 | NTc.Cm19 | ASP 25 | - | VdWContact |
| TYR 14 | NTc.Cm19 | CYS 26 | - | VdWContact |
| TYR 14 | NTc.Cm19 | ILE 27 | - | Hydrophobic |
| TYR 14 | NTc.Cm19 | ILE 27 | - | VdWContact |
| TYR 14 | NTc.Cm19 | THR 31 | - | Hydrophobic |
| LEU 18 | NTc.Cm15 | ILE 27 | - | Hydrophobic |
| SER 19 | NTc.Cm14 | ASP 25 | - | HBDonor |
| SER 19 | NTc.Cm14 | ASP 25 | - | VdWContact |
| LEU 22 | NTc.Cm11 | TRP 19 | - | Hydrophobic |
| LEU 22 | NTc.Cm11 | ILE 27 | - | Hydrophobic |
| LYS 25 | NTc.Cm8 | ILE 17 | - | VdWContact |
| ASP 35 | cxb1.1 | ALA 189 | - | VdWContact |
| ASP 37 | cxb1.5 | VAL 186 | - | Hydrophobic |
| ASP 37 | cxb1.5 | VAL 186 | - | VdWContact |
| ASP 37 | cxb1.5 | THR 187 | - | HBAcceptor |
| ASP 37 | cxb1.5 | THR 187 | - | VdWContact |
| ASP 37 | cxb1.5 | SER 188 | - | VdWContact |
| ASP 37 | cxb1.5 | ALA 189 | - | HBAcceptor |
| ASP 37 | cxb1.5 | ALA 189 | - | VdWContact |
| HIS 39 | cxb1.7 | VAL 186 | - | Hydrophobic |
| HIS 39 | cxb1.7 | PHE 199 | - | Hydrophobic |
| HIS 39 | cxb1.7 | PHE 199 | - | PiStacking |
| HIS 39 | cxb1.7 | PHE 199 | - | VdWContact |
| LEU 40 | cxb1.8 | GLU 202 | - | Hydrophobic |
| VAL 44 | cxb1.15 | MET 33 | - | Hydrophobic |
| VAL 44 | cxb1.15 | MET 33 | - | VdWContact |
| HIS 46 | cxb1.17 | MET 33 | - | Hydrophobic |
| GLN 49 | B1.1 | PHE 14 | - | HBDonor |
| GLN 49 | B1.1 | PHE 14 | - | VdWContact |
| ARG 50 | B1.2 | TRP 19 | - | VdWContact |
| ARG 50 | B1.2 | VAL 32 | - | Hydrophobic |
| ARG 50 | B1.2 | VAL 32 | - | VdWContact |
| SER 51 | B1.3 | VAL 32 | - | VdWContact |
| SER 51 | B1.3 | MET 33 | - | HBAcceptor |
| SER 51 | B1.3 | MET 33 | - | HBDonor |
| SER 51 | B1.3 | MET 33 | - | VdWContact |
| ILE 52 | B1.4 | ILE 27 | - | Hydrophobic |
| ILE 52 | B1.4 | ILE 27 | - | VdWContact |
| ILE 52 | B1.4 | THR 31 | - | VdWContact |
| ILE 52 | B1.4 | VAL 32 | - | Hydrophobic |
| CYS 53 | B1.5 | THR 31 | - | HBDonor |
| CYS 53 | B1.5 | THR 31 | - | VdWContact |
