Predicted complex interactions
CCL28_HUMAN + ACKR3
SUMMARY
- Chemokine
- CCL28_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- ACKR3 View partner entry
- Partner description
- UniProt: P25106; Gene: ackr3_human; Family: Chemokine
- Interactions detected
- 135
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| SER 1 | NTc.Cm29 | HIS 4 | - | HBDonor |
| SER 1 | NTc.Cm29 | HIS 4 | - | VdWContact |
| SER 1 | NTc.Cm29 | LEU 5 | - | HBDonor |
| SER 1 | NTc.Cm29 | LEU 5 | - | VdWContact |
| SER 1 | NTc.Cm29 | PHE 6 | - | CationPi |
| SER 1 | NTc.Cm29 | PHE 6 | - | HBDonor |
| SER 1 | NTc.Cm29 | PHE 6 | - | VdWContact |
| GLU 2 | NTc.Cm28 | LEU 3 | - | VdWContact |
| GLU 2 | NTc.Cm28 | HIS 4 | - | VdWContact |
| GLU 2 | NTc.Cm28 | LEU 5 | - | HBDonor |
| GLU 2 | NTc.Cm28 | LEU 5 | - | Hydrophobic |
| GLU 2 | NTc.Cm28 | LEU 5 | - | VdWContact |
| GLU 2 | NTc.Cm28 | THR 187 | - | HBAcceptor |
| GLU 2 | NTc.Cm28 | THR 187 | - | VdWContact |
| ALA 3 | NTc.Cm27 | LEU 3 | - | Hydrophobic |
| ALA 3 | NTc.Cm27 | LEU 3 | - | VdWContact |
| ILE 4 | NTc.Cm26 | VAL 186 | - | Hydrophobic |
| ILE 4 | NTc.Cm26 | VAL 186 | - | VdWContact |
| ILE 4 | NTc.Cm26 | THR 187 | - | VdWContact |
| ILE 4 | NTc.Cm26 | SER 188 | - | VdWContact |
| ILE 4 | NTc.Cm26 | ALA 189 | - | Hydrophobic |
| ILE 4 | NTc.Cm26 | ALA 189 | - | VdWContact |
| LEU 5 | NTc.Cm25 | LYS 184 | - | Hydrophobic |
| LEU 5 | NTc.Cm25 | LYS 184 | - | VdWContact |
| LEU 5 | NTc.Cm25 | VAL 186 | - | Hydrophobic |
| LEU 5 | NTc.Cm25 | VAL 186 | - | VdWContact |
| LEU 5 | NTc.Cm25 | PHE 199 | - | Hydrophobic |
| LEU 5 | NTc.Cm25 | PHE 199 | - | VdWContact |
| ILE 7 | NTc.Cm23 | ALA 189 | - | Hydrophobic |
| ILE 7 | NTc.Cm23 | ALA 189 | - | VdWContact |
| ALA 8 | NTc.Cm22 | PHE 6 | - | Hydrophobic |
| CYS 12 | NTc.Cm18 | GLU 202 | - | VdWContact |
| THR 13 | NTc.Cm17 | GLU 202 | - | HBDonor |
| THR 13 | NTc.Cm17 | GLU 202 | - | VdWContact |
| GLU 14 | NTc.Cm16 | GLU 202 | - | Hydrophobic |
| GLU 14 | NTc.Cm16 | HIS 203 | - | VdWContact |
| HIS 18 | NTc.Cm12 | LYS 206 | 5.32x33 | HBAcceptor |
| HIS 18 | NTc.Cm12 | LYS 206 | 5.32x33 | VdWContact |
| ILE 19 | NTc.Cm11 | LYS 206 | 5.32x33 | VdWContact |
| ILE 19 | NTc.Cm11 | HIS 281 | 6.64x64 | VdWContact |
| SER 20 | NTc.Cm10 | ILE 279 | 6.62x62 | VdWContact |
| SER 20 | NTc.Cm10 | HIS 281 | 6.64x64 | VdWContact |
| ARG 22 | NTc.Cm8 | SER 278 | 6.61x61 | HBAcceptor |
| ARG 22 | NTc.Cm8 | SER 278 | 6.61x61 | VdWContact |
| ARG 22 | NTc.Cm8 | HIS 281 | 6.64x64 | VdWContact |
| ARG 22 | NTc.Cm8 | TYR 282 | - | VdWContact |
| ARG 22 | NTc.Cm8 | ILE 283 | - | VdWContact |
| ARG 22 | NTc.Cm8 | PRO 284 | - | VdWContact |
| LEU 23 | NTc.Cm7 | ILE 279 | 6.62x62 | Hydrophobic |
| LEU 23 | NTc.Cm7 | HIS 281 | 6.64x64 | VdWContact |
| GLU 25 | NTc.Cm5 | PHE 285 | - | VdWContact |
| ARG 26 | NTc.Cm4 | ASP 275 | 6.58x58 | Cationic |
| ARG 26 | NTc.Cm4 | ASP 275 | 6.58x58 | HBDonor |
| ARG 26 | NTc.Cm4 | ASP 275 | 6.58x58 | VdWContact |
| ARG 26 | NTc.Cm4 | SER 278 | 6.61x61 | HBDonor |
| ARG 26 | NTc.Cm4 | SER 278 | 6.61x61 | VdWContact |
| ARG 26 | NTc.Cm4 | PHE 285 | - | VdWContact |
| ARG 26 | NTc.Cm4 | GLU 290 | 7.28x27 | Cationic |
| ARG 26 | NTc.Cm4 | GLU 290 | 7.28x27 | Hydrophobic |
| ARG 26 | NTc.Cm4 | GLU 290 | 7.28x27 | VdWContact |
| ARG 26 | NTc.Cm4 | LEU 293 | 7.31x30 | VdWContact |
| VAL 27 | NTc.Cm3 | PHE 285 | - | VdWContact |
| ASN 28 | NTc.Cm2 | CYS 34 | - | Hydrophobic |
| ILE 32 | cxb1.1 | VAL 29 | - | Hydrophobic |
| ILE 32 | cxb1.1 | VAL 29 | - | VdWContact |
| ARG 34 | cxb1.5 | ILE 17 | - | VdWContact |
| ARG 34 | cxb1.5 | TRP 19 | - | Hydrophobic |
| ARG 34 | cxb1.5 | TRP 19 | - | VdWContact |
| LYS 49 | B1.5 | ASP 275 | 6.58x58 | Cationic |
| LYS 49 | B1.5 | GLU 290 | 7.28x27 | Cationic |
| LYS 49 | B1.5 | GLU 290 | 7.28x27 | HBDonor |
| LYS 49 | B1.5 | GLU 290 | 7.28x27 | Hydrophobic |
| LYS 49 | B1.5 | GLU 290 | 7.28x27 | VdWContact |
| LYS 49 | B1.5 | LEU 293 | 7.31x30 | VdWContact |
| LYS 49 | B1.5 | PHE 294 | 7.32x31 | VdWContact |
| ARG 50 | B1.6 | ASN 108 | - | HBDonor |
| ARG 50 | B1.6 | ASN 108 | - | VdWContact |
| ARG 50 | B1.6 | TYR 195 | - | VdWContact |
| ARG 50 | B1.6 | ARG 197 | 45.51x51 | HBAcceptor |
| ARG 50 | B1.6 | ARG 197 | 45.51x51 | VdWContact |
| ARG 51 | B1.7 | LEU 209 | 5.35x36 | VdWContact |
| ARG 51 | B1.7 | GLU 213 | 5.39x40 | Cationic |
| ARG 51 | B1.7 | GLU 213 | 5.39x40 | HBDonor |
| ARG 51 | B1.7 | GLU 213 | 5.39x40 | VdWContact |
| ARG 51 | B1.7 | ASP 275 | 6.58x58 | Cationic |
| ARG 51 | B1.7 | ASP 275 | 6.58x58 | HBDonor |
| ARG 51 | B1.7 | ASP 275 | 6.58x58 | VdWContact |
| ARG 51 | B1.7 | ILE 279 | 6.62x62 | VdWContact |
| ARG 52 | b1b2.4 | GLU 202 | - | Cationic |
| LYS 63 | B2.2 | ILE 27 | - | Hydrophobic |
| LYS 63 | B2.2 | ILE 27 | - | VdWContact |
| MET 66 | B2.5 | VAL 29 | - | Hydrophobic |
| MET 66 | B2.5 | VAL 29 | - | VdWContact |
| MET 66 | B2.5 | ASP 30 | - | VdWContact |
| LYS 67 | B2.6 | ILE 27 | - | Hydrophobic |
| LYS 67 | B2.6 | ILE 27 | - | VdWContact |
| LYS 67 | B2.6 | ASP 30 | - | VdWContact |
| VAL 68 | b2b3.2 | ASP 30 | - | VdWContact |
| GLN 69 | b2b3.11 | ASP 30 | - | VdWContact |
| GLN 69 | b2b3.11 | THR 31 | - | HBAcceptor |
| GLN 69 | b2b3.11 | THR 31 | - | VdWContact |
| GLN 69 | b2b3.11 | VAL 32 | - | Hydrophobic |
| GLN 69 | b2b3.11 | VAL 32 | - | VdWContact |
| ALA 70 | b2b3.12 | ASP 30 | - | HBDonor |
| ALA 70 | b2b3.12 | ASP 30 | - | Hydrophobic |
| ALA 70 | b2b3.12 | ASP 30 | - | VdWContact |
| ALA 70 | b2b3.12 | THR 31 | - | HBAcceptor |
| ALA 70 | b2b3.12 | THR 31 | - | VdWContact |
| ALA 71 | B3.1 | ASP 30 | - | HBDonor |
| ALA 71 | B3.1 | ASP 30 | - | VdWContact |
| LYS 72 | B3.2 | VAL 32 | - | Hydrophobic |
| GLY 77 | b3h.3 | THR 31 | - | VdWContact |
| GLY 77 | b3h.3 | VAL 32 | - | VdWContact |
| GLY 77 | b3h.3 | MET 33 | - | HBAcceptor |
| GLY 77 | b3h.3 | MET 33 | - | VdWContact |
| ASN 78 | b3h.4 | THR 31 | - | VdWContact |
| VAL 79 | H.1 | THR 31 | - | HBDonor |
| VAL 79 | H.1 | THR 31 | - | VdWContact |
| VAL 79 | H.1 | VAL 32 | - | VdWContact |
| VAL 79 | H.1 | MET 33 | - | Hydrophobic |
| VAL 79 | H.1 | MET 33 | - | VdWContact |
| CYS 80 | H.2 | VAL 29 | - | Hydrophobic |
| CYS 80 | H.2 | THR 31 | - | HBDonor |
| CYS 80 | H.2 | THR 31 | - | Hydrophobic |
| CYS 80 | H.2 | THR 31 | - | VdWContact |
| HIS 81 | H.3 | PHE 14 | - | Hydrophobic |
| ARG 82 | H.4 | PHE 14 | - | Hydrophobic |
| ARG 82 | H.4 | PHE 14 | - | VdWContact |
| ARG 82 | H.4 | ILE 17 | - | Hydrophobic |
| ARG 82 | H.4 | ILE 17 | - | VdWContact |
| LYS 83 | H.5 | ILE 17 | - | VdWContact |
| LYS 84 | H.6 | GLY 12 | - | VdWContact |
| LYS 84 | H.6 | ASN 13 | - | VdWContact |
| LYS 84 | H.6 | ASP 16 | - | Cationic |
| LYS 84 | H.6 | ILE 17 | - | Hydrophobic |
