Predicted complex interactions
CCL4_HUMAN + ACKR3
SUMMARY
- Chemokine
- CCL4_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- ACKR3 View partner entry
- Partner description
- UniProt: P25106; Gene: ackr3_human; Family: Chemokine
- Interactions detected
- 73
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ALA 1 | NTc.Cm33 | HIS 121 | 3.29x29 | Hydrophobic |
| ALA 1 | NTc.Cm33 | PHE 124 | 3.32x32 | Hydrophobic |
| ALA 1 | NTc.Cm33 | ASP 179 | 4.60x61 | Cationic |
| ALA 1 | NTc.Cm33 | ASP 179 | 4.60x61 | VdWContact |
| PRO 2 | NTc.Cm32 | TYR 268 | 6.51x51 | Hydrophobic |
| PRO 2 | NTc.Cm32 | TYR 268 | 6.51x51 | VdWContact |
| PRO 2 | NTc.Cm32 | LEU 297 | 7.35x34 | Hydrophobic |
| PRO 2 | NTc.Cm32 | GLN 301 | 7.39x38 | Hydrophobic |
| PRO 2 | NTc.Cm32 | GLN 301 | 7.39x38 | VdWContact |
| MET 3 | NTc.Cm31 | HIS 121 | 3.29x29 | Hydrophobic |
| MET 3 | NTc.Cm31 | LEU 183 | 4.64x65 | Hydrophobic |
| MET 3 | NTc.Cm31 | LEU 183 | 4.64x65 | VdWContact |
| MET 3 | NTc.Cm31 | CYS 196 | 45.50x50 | VdWContact |
| MET 3 | NTc.Cm31 | ARG 197 | 45.51x51 | VdWContact |
| MET 3 | NTc.Cm31 | SER 198 | 45.52x52 | VdWContact |
| GLY 4 | NTc.Cm30 | LEU 297 | 7.35x34 | VdWContact |
| ASP 6 | NTc.Cm28 | TYR 195 | - | VdWContact |
| ASP 6 | NTc.Cm28 | ARG 197 | 45.51x51 | Anionic |
| ASP 6 | NTc.Cm28 | ARG 197 | 45.51x51 | HBAcceptor |
| ASP 6 | NTc.Cm28 | ARG 197 | 45.51x51 | VdWContact |
| PRO 7 | NTc.Cm27 | ARG 197 | 45.51x51 | HBAcceptor |
| PRO 7 | NTc.Cm27 | ARG 197 | 45.51x51 | VdWContact |
| PRO 7 | NTc.Cm27 | GLU 290 | 7.28x27 | VdWContact |
| THR 9 | NTc.Cm25 | MET 33 | - | VdWContact |
| ALA 10 | NTc.Cm24 | MET 33 | - | Hydrophobic |
| CYS 11 | NTc.Cm23 | VAL 32 | - | HBAcceptor |
| PHE 13 | NTc.Cm21 | VAL 32 | - | Hydrophobic |
| PHE 13 | NTc.Cm21 | VAL 32 | - | VdWContact |
| PHE 13 | NTc.Cm21 | PHE 285 | - | Hydrophobic |
| PHE 13 | NTc.Cm21 | PHE 285 | - | VdWContact |
| SER 14 | NTc.Cm20 | ASP 30 | - | HBAcceptor |
| SER 14 | NTc.Cm20 | ASP 30 | - | VdWContact |
| TYR 15 | NTc.Cm19 | ILE 27 | - | VdWContact |
| THR 16 | NTc.Cm18 | VAL 29 | - | Hydrophobic |
| THR 16 | NTc.Cm18 | VAL 29 | - | VdWContact |
| ALA 17 | NTc.Cm17 | ILE 27 | - | Hydrophobic |
| ALA 17 | NTc.Cm17 | ILE 27 | - | VdWContact |
| ARG 18 | NTc.Cm16 | ASP 25 | - | Cationic |
| ARG 18 | NTc.Cm16 | ASP 25 | - | HBDonor |
| ARG 18 | NTc.Cm16 | ASP 25 | - | VdWContact |
| ARG 18 | NTc.Cm16 | CYS 26 | - | Cationic |
| ARG 18 | NTc.Cm16 | CYS 26 | - | VdWContact |
| PRO 21 | NTc.Cm13 | TRP 19 | - | Hydrophobic |
| PRO 21 | NTc.Cm13 | TRP 19 | - | VdWContact |
| PHE 24 | NTc.Cm10 | TRP 19 | - | Hydrophobic |
| PHE 24 | NTc.Cm10 | TRP 19 | - | VdWContact |
| SER 33 | NTc.Cm1 | ILE 205 | 5.31x32 | VdWContact |
| SER 33 | NTc.Cm1 | LYS 206 | 5.32x33 | VdWContact |
| LEU 34 | CX.1 | ILE 205 | 5.31x32 | Hydrophobic |
| LEU 34 | CX.1 | LEU 209 | 5.35x36 | Hydrophobic |
| CYS 35 | CX.5 | LYS 206 | 5.32x33 | HBAcceptor |
| CYS 35 | CX.5 | LYS 206 | 5.32x33 | VdWContact |
| SER 36 | cxb1.1 | HIS 281 | 6.64x64 | VdWContact |
| VAL 41 | cxb1.8 | THR 31 | - | Hydrophobic |
| ARG 46 | cxb1.16 | PHE 14 | - | Hydrophobic |
| ARG 46 | cxb1.16 | PHE 14 | - | VdWContact |
| ARG 46 | cxb1.16 | ASP 16 | - | HBDonor |
| ARG 46 | cxb1.16 | ASP 16 | - | VdWContact |
| ARG 46 | cxb1.16 | ILE 17 | - | Hydrophobic |
| ARG 46 | cxb1.16 | ILE 17 | - | VdWContact |
| SER 47 | B1.1 | PHE 14 | - | VdWContact |
| LYS 48 | B1.2 | PHE 14 | - | Hydrophobic |
| LYS 48 | B1.2 | PHE 14 | - | VdWContact |
| LYS 48 | B1.2 | ILE 17 | - | Hydrophobic |
| LYS 48 | B1.2 | ILE 17 | - | VdWContact |
| GLN 49 | B1.3 | THR 31 | - | Hydrophobic |
| GLN 49 | B1.3 | THR 31 | - | VdWContact |
| GLN 49 | B1.3 | MET 33 | - | VdWContact |
| VAL 50 | B1.4 | VAL 29 | - | Hydrophobic |
| CYS 51 | B1.5 | VAL 29 | - | Hydrophobic |
| CYS 51 | B1.5 | VAL 29 | - | VdWContact |
| CYS 51 | B1.5 | THR 31 | - | Hydrophobic |
| CYS 51 | B1.5 | THR 31 | - | VdWContact |
