Predicted complex interactions
CCL8_HUMAN + ACKR3
SUMMARY
- Chemokine
- CCL8_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- ACKR3 View partner entry
- Partner description
- UniProt: P25106; Gene: ackr3_human; Family: Chemokine
- Interactions detected
- 62
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLN 1 | NTc.Cm33 | TRP 100 | 2.60x60 | VdWContact |
| GLN 1 | NTc.Cm33 | HIS 121 | 3.29x29 | HBDonor |
| GLN 1 | NTc.Cm33 | HIS 121 | 3.29x29 | Hydrophobic |
| GLN 1 | NTc.Cm33 | HIS 121 | 3.29x29 | VdWContact |
| GLN 1 | NTc.Cm33 | PHE 124 | 3.32x32 | Hydrophobic |
| GLN 1 | NTc.Cm33 | ASP 179 | 4.60x61 | Cationic |
| PRO 2 | NTc.Cm32 | LEU 297 | 7.35x34 | Hydrophobic |
| PRO 2 | NTc.Cm32 | LEU 297 | 7.35x34 | VdWContact |
| PRO 2 | NTc.Cm32 | HIS 298 | 7.36x35 | Hydrophobic |
| PRO 2 | NTc.Cm32 | GLN 301 | 7.39x38 | VdWContact |
| ASP 3 | NTc.Cm31 | LEU 209 | 5.35x36 | VdWContact |
| SER 4 | NTc.Cm30 | ARG 197 | 45.51x51 | HBAcceptor |
| SER 4 | NTc.Cm30 | ARG 197 | 45.51x51 | VdWContact |
| VAL 5 | NTc.Cm29 | GLU 290 | 7.28x27 | VdWContact |
| VAL 5 | NTc.Cm29 | LEU 297 | 7.35x34 | Hydrophobic |
| SER 6 | NTc.Cm28 | ARG 197 | 45.51x51 | HBAcceptor |
| SER 6 | NTc.Cm28 | ARG 197 | 45.51x51 | VdWContact |
| SER 6 | NTc.Cm28 | PHE 294 | 7.32x31 | VdWContact |
| ILE 7 | NTc.Cm27 | TYR 8 | - | Hydrophobic |
| ILE 7 | NTc.Cm27 | TYR 8 | - | VdWContact |
| ILE 7 | NTc.Cm27 | TYR 195 | - | Hydrophobic |
| ILE 7 | NTc.Cm27 | ARG 197 | 45.51x51 | HBAcceptor |
| ILE 7 | NTc.Cm27 | ARG 197 | 45.51x51 | VdWContact |
| PHE 13 | NTc.Cm21 | PHE 285 | - | Hydrophobic |
| PHE 13 | NTc.Cm21 | PHE 285 | - | PiStacking |
| PHE 13 | NTc.Cm21 | PHE 285 | - | VdWContact |
| ASN 14 | NTc.Cm20 | ILE 27 | - | Hydrophobic |
| ASN 14 | NTc.Cm20 | ILE 27 | - | VdWContact |
| ASN 14 | NTc.Cm20 | VAL 28 | - | HBDonor |
| ASN 14 | NTc.Cm20 | ASP 30 | - | VdWContact |
| VAL 15 | NTc.Cm19 | ILE 27 | - | Hydrophobic |
| VAL 15 | NTc.Cm19 | ILE 27 | - | VdWContact |
| VAL 15 | NTc.Cm19 | VAL 29 | - | VdWContact |
| ILE 16 | NTc.Cm18 | ILE 27 | - | VdWContact |
| ILE 16 | NTc.Cm18 | VAL 29 | - | Hydrophobic |
| ASN 17 | NTc.Cm17 | ASP 25 | - | Hydrophobic |
| ASN 17 | NTc.Cm17 | ASP 25 | - | VdWContact |
| ASN 17 | NTc.Cm17 | ILE 27 | - | Hydrophobic |
| ASN 17 | NTc.Cm17 | ILE 27 | - | VdWContact |
| ARG 18 | NTc.Cm16 | ASP 25 | - | VdWContact |
| ARG 18 | NTc.Cm16 | CYS 26 | - | Cationic |
| ARG 18 | NTc.Cm16 | CYS 26 | - | VdWContact |
| ARG 24 | NTc.Cm10 | TRP 19 | - | VdWContact |
| ILE 34 | CX.1 | ILE 205 | 5.31x32 | Hydrophobic |
| ILE 34 | CX.1 | ILE 205 | 5.31x32 | VdWContact |
| ILE 34 | CX.1 | LYS 206 | 5.32x33 | Hydrophobic |
| ILE 34 | CX.1 | LYS 206 | 5.32x33 | VdWContact |
| PRO 37 | cxb1.2 | HIS 281 | 6.64x64 | Hydrophobic |
| PRO 37 | cxb1.2 | HIS 281 | 6.64x64 | VdWContact |
| ILE 42 | cxb1.10 | THR 31 | - | Hydrophobic |
| LYS 49 | B1.3 | ILE 17 | - | HBDonor |
| LYS 49 | B1.3 | ILE 17 | - | Hydrophobic |
| LYS 49 | B1.3 | ILE 17 | - | VdWContact |
| LYS 49 | B1.3 | TRP 19 | - | Hydrophobic |
| LYS 49 | B1.3 | TRP 19 | - | VdWContact |
| GLU 50 | B1.4 | PHE 14 | - | Hydrophobic |
| GLU 50 | B1.4 | PHE 14 | - | VdWContact |
| VAL 51 | B1.5 | VAL 29 | - | Hydrophobic |
| VAL 51 | B1.5 | VAL 29 | - | VdWContact |
| CYS 52 | B1.6 | VAL 29 | - | Hydrophobic |
| CYS 52 | B1.6 | VAL 29 | - | VdWContact |
| CYS 52 | B1.6 | THR 31 | - | VdWContact |
