Predicted complex interactions
CX3CL1_HUMAN + ACKR3
SUMMARY
- Chemokine
- CX3CL1_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- ACKR3 View partner entry
- Partner description
- UniProt: P25106; Gene: ackr3_human; Family: Chemokine
- Interactions detected
- 68
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLN 1 | NTc.Cm37 | HIS 121 | 3.29x29 | Hydrophobic |
| GLN 1 | NTc.Cm37 | HIS 121 | 3.29x29 | VdWContact |
| GLN 1 | NTc.Cm37 | PHE 124 | 3.32x32 | Hydrophobic |
| GLN 1 | NTc.Cm37 | SER 125 | 3.33x33 | VdWContact |
| GLN 1 | NTc.Cm37 | TYR 268 | 6.51x51 | HBDonor |
| GLN 1 | NTc.Cm37 | TYR 268 | 6.51x51 | VdWContact |
| GLN 1 | NTc.Cm37 | GLN 301 | 7.39x38 | HBDonor |
| GLN 1 | NTc.Cm37 | GLN 301 | 7.39x38 | VdWContact |
| HIS 2 | NTc.Cm36 | LEU 297 | 7.35x34 | Hydrophobic |
| HIS 2 | NTc.Cm36 | LEU 297 | 7.35x34 | VdWContact |
| HIS 2 | NTc.Cm36 | HIS 298 | 7.36x35 | Hydrophobic |
| HIS 3 | NTc.Cm35 | ASP 179 | 4.60x61 | VdWContact |
| HIS 3 | NTc.Cm35 | TYR 200 | - | Hydrophobic |
| HIS 3 | NTc.Cm35 | TYR 200 | - | VdWContact |
| HIS 3 | NTc.Cm35 | LEU 209 | 5.35x36 | Hydrophobic |
| HIS 3 | NTc.Cm35 | MET 212 | 5.38x39 | Hydrophobic |
| HIS 3 | NTc.Cm35 | MET 212 | 5.38x39 | VdWContact |
| GLY 4 | NTc.Cm34 | ARG 197 | 45.51x51 | HBAcceptor |
| GLY 4 | NTc.Cm34 | ARG 197 | 45.51x51 | VdWContact |
| VAL 5 | NTc.Cm33 | SER 198 | 45.52x52 | VdWContact |
| VAL 5 | NTc.Cm33 | TYR 200 | - | Hydrophobic |
| VAL 5 | NTc.Cm33 | LEU 209 | 5.35x36 | Hydrophobic |
| VAL 5 | NTc.Cm33 | LEU 209 | 5.35x36 | VdWContact |
| THR 6 | NTc.Cm32 | ARG 197 | 45.51x51 | HBAcceptor |
| THR 6 | NTc.Cm32 | ARG 197 | 45.51x51 | VdWContact |
| LYS 7 | NTc.Cm31 | ASP 275 | 6.58x58 | Cationic |
| LYS 7 | NTc.Cm31 | ASP 275 | 6.58x58 | HBDonor |
| LYS 7 | NTc.Cm31 | ASP 275 | 6.58x58 | VdWContact |
| LYS 7 | NTc.Cm31 | GLU 290 | 7.28x27 | Cationic |
| LYS 7 | NTc.Cm31 | GLU 290 | 7.28x27 | HBDonor |
| LYS 7 | NTc.Cm31 | GLU 290 | 7.28x27 | VdWContact |
| ASN 9 | NTc.Cm29 | PHE 285 | - | VdWContact |
| ILE 10 | NTc.Cm28 | VAL 29 | - | Hydrophobic |
| ILE 10 | NTc.Cm28 | THR 31 | - | Hydrophobic |
| ILE 10 | NTc.Cm28 | THR 31 | - | VdWContact |
| ILE 10 | NTc.Cm28 | MET 33 | - | Hydrophobic |
| THR 11 | NTc.Cm27 | HIS 281 | 6.64x64 | Hydrophobic |
| THR 11 | NTc.Cm27 | HIS 281 | 6.64x64 | VdWContact |
| LYS 14 | NTc.Cm24 | ASP 25 | - | Cationic |
| LYS 14 | NTc.Cm24 | ILE 27 | - | Hydrophobic |
| LYS 14 | NTc.Cm24 | ILE 27 | - | VdWContact |
| MET 15 | NTc.Cm23 | ILE 27 | - | VdWContact |
| LYS 18 | NTc.Cm20 | TRP 19 | - | VdWContact |
| ILE 19 | NTc.Cm19 | TRP 19 | - | Hydrophobic |
| ILE 19 | NTc.Cm19 | TRP 19 | - | VdWContact |
| PRO 20 | NTc.Cm18 | TRP 19 | - | Hydrophobic |
| PRO 20 | NTc.Cm18 | TRP 19 | - | VdWContact |
| LEU 23 | NTc.Cm15 | ILE 17 | - | Hydrophobic |
| LEU 23 | NTc.Cm15 | TRP 19 | - | Hydrophobic |
| GLN 28 | NTc.Cm10 | MET 33 | - | VdWContact |
| ALA 32 | NTc.Cm6 | ILE 205 | 5.31x32 | Hydrophobic |
| ALA 32 | NTc.Cm6 | ILE 205 | 5.31x32 | VdWContact |
| SER 33 | NTc.Cm5 | ILE 205 | 5.31x32 | VdWContact |
| CYS 34 | NTc.Cm4 | LYS 206 | 5.32x33 | VdWContact |
| ARG 37 | NTc.Cm1 | GLU 202 | - | Cationic |
| ARG 37 | NTc.Cm1 | GLU 202 | - | HBDonor |
| ARG 37 | NTc.Cm1 | GLU 202 | - | VdWContact |
| GLN 45 | cxb1.5 | PHE 14 | - | HBDonor |
| GLN 45 | cxb1.5 | PHE 14 | - | VdWContact |
| LEU 48 | cxb1.10 | VAL 29 | - | VdWContact |
| LEU 48 | cxb1.10 | THR 31 | - | Hydrophobic |
| LEU 48 | cxb1.10 | THR 31 | - | VdWContact |
| LEU 48 | cxb1.10 | MET 33 | - | Hydrophobic |
| PHE 49 | cxb1.11 | VAL 29 | - | Hydrophobic |
| PHE 49 | cxb1.11 | VAL 29 | - | VdWContact |
| CYS 50 | cxb1.14 | VAL 29 | - | Hydrophobic |
| CYS 50 | cxb1.14 | VAL 29 | - | VdWContact |
| GLY 76 | b2b3.11 | LEU 3 | - | VdWContact |
