Predicted complex interactions
CXCL1_HUMAN + ACKR3
SUMMARY
- Chemokine
- CXCL1_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- ACKR3 View partner entry
- Partner description
- UniProt: P25106; Gene: ackr3_human; Family: Chemokine
- Interactions detected
- 128
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ALA 1 | NTc.Cm42 | PHE 129 | 3.37x37 | Hydrophobic |
| ALA 1 | NTc.Cm42 | PHE 129 | 3.37x37 | VdWContact |
| ALA 1 | NTc.Cm42 | ASP 179 | 4.60x61 | Cationic |
| ALA 1 | NTc.Cm42 | ASP 179 | 4.60x61 | VdWContact |
| ALA 1 | NTc.Cm42 | SER 216 | 5.42x43 | HBAcceptor |
| ALA 1 | NTc.Cm42 | SER 216 | 5.42x43 | VdWContact |
| SER 2 | NTc.Cm41 | PHE 124 | 3.32x32 | VdWContact |
| SER 2 | NTc.Cm41 | LEU 128 | 3.36x36 | VdWContact |
| SER 2 | NTc.Cm41 | TYR 268 | 6.51x51 | VdWContact |
| SER 2 | NTc.Cm41 | GLN 301 | 7.39x38 | HBDonor |
| SER 2 | NTc.Cm41 | GLN 301 | 7.39x38 | VdWContact |
| VAL 3 | NTc.Cm40 | TYR 268 | 6.51x51 | Hydrophobic |
| VAL 3 | NTc.Cm40 | TYR 268 | 6.51x51 | VdWContact |
| VAL 3 | NTc.Cm40 | VAL 272 | 6.55x55 | Hydrophobic |
| VAL 3 | NTc.Cm40 | VAL 272 | 6.55x55 | VdWContact |
| VAL 3 | NTc.Cm40 | LEU 297 | 7.35x34 | Hydrophobic |
| VAL 3 | NTc.Cm40 | LEU 297 | 7.35x34 | VdWContact |
| VAL 3 | NTc.Cm40 | GLN 301 | 7.39x38 | Hydrophobic |
| VAL 3 | NTc.Cm40 | GLN 301 | 7.39x38 | VdWContact |
| ALA 4 | NTc.Cm39 | LEU 297 | 7.35x34 | Hydrophobic |
| ALA 4 | NTc.Cm39 | HIS 298 | 7.36x35 | Hydrophobic |
| ALA 4 | NTc.Cm39 | HIS 298 | 7.36x35 | VdWContact |
| THR 5 | NTc.Cm38 | HIS 121 | 3.29x29 | Hydrophobic |
| GLU 6 | NTc.Cm37 | LYS 40 | - | Anionic |
| GLU 6 | NTc.Cm37 | ASN 108 | - | HBAcceptor |
| GLU 6 | NTc.Cm37 | ASN 108 | - | VdWContact |
| GLU 6 | NTc.Cm37 | TYR 195 | - | VdWContact |
| GLU 6 | NTc.Cm37 | ARG 197 | 45.51x51 | Anionic |
| GLU 6 | NTc.Cm37 | ARG 197 | 45.51x51 | HBAcceptor |
| GLU 6 | NTc.Cm37 | ARG 197 | 45.51x51 | VdWContact |
| GLU 6 | NTc.Cm37 | PHE 294 | 7.32x31 | VdWContact |
| LEU 7 | NTc.Cm36 | ARG 197 | 45.51x51 | Hydrophobic |
| LEU 7 | NTc.Cm36 | ARG 197 | 45.51x51 | VdWContact |
| LEU 7 | NTc.Cm36 | SER 198 | 45.52x52 | VdWContact |
| LEU 7 | NTc.Cm36 | LEU 209 | 5.35x36 | VdWContact |
| ARG 8 | NTc.Cm35 | ASP 275 | 6.58x58 | Cationic |
| ARG 8 | NTc.Cm35 | ASP 275 | 6.58x58 | HBDonor |
| ARG 8 | NTc.Cm35 | ASP 275 | 6.58x58 | VdWContact |
| ARG 8 | NTc.Cm35 | GLU 290 | 7.28x27 | Cationic |
| ARG 8 | NTc.Cm35 | GLU 290 | 7.28x27 | HBDonor |
| ARG 8 | NTc.Cm35 | GLU 290 | 7.28x27 | VdWContact |
| ARG 8 | NTc.Cm35 | LEU 293 | 7.31x30 | VdWContact |
| ARG 8 | NTc.Cm35 | LEU 297 | 7.35x34 | VdWContact |
| CYS 9 | NTc.Cm34 | ARG 197 | 45.51x51 | Anionic |
| GLN 10 | NTc.Cm33 | ILE 205 | 5.31x32 | VdWContact |
| LEU 12 | NTc.Cm31 | PHE 199 | - | Hydrophobic |
| LEU 12 | NTc.Cm31 | PHE 199 | - | VdWContact |
| LEU 12 | NTc.Cm31 | TYR 200 | - | Hydrophobic |
| LEU 12 | NTc.Cm31 | TYR 200 | - | VdWContact |
| LEU 12 | NTc.Cm31 | GLU 202 | - | Hydrophobic |
| LEU 12 | NTc.Cm31 | ILE 205 | 5.31x32 | Hydrophobic |
| LEU 12 | NTc.Cm31 | ILE 205 | 5.31x32 | VdWContact |
| GLN 13 | NTc.Cm30 | PHE 199 | - | Hydrophobic |
| GLN 13 | NTc.Cm30 | GLU 202 | - | HBDonor |
| GLN 13 | NTc.Cm30 | GLU 202 | - | Hydrophobic |
| GLN 13 | NTc.Cm30 | GLU 202 | - | VdWContact |
| LEU 15 | NTc.Cm28 | PHE 6 | - | Hydrophobic |
| ILE 18 | NTc.Cm25 | TYR 8 | - | Hydrophobic |
| HIS 19 | NTc.Cm24 | PHE 14 | - | VdWContact |
| HIS 19 | NTc.Cm24 | ILE 17 | - | Hydrophobic |
| PRO 20 | NTc.Cm23 | ILE 17 | - | Hydrophobic |
| PRO 20 | NTc.Cm23 | TRP 19 | - | Hydrophobic |
| PRO 20 | NTc.Cm23 | TRP 19 | - | VdWContact |
| ASN 22 | NTc.Cm21 | TYR 8 | - | VdWContact |
| ILE 23 | NTc.Cm20 | ILE 27 | - | Hydrophobic |
| ILE 23 | NTc.Cm20 | ILE 27 | - | VdWContact |
| GLN 24 | NTc.Cm19 | ILE 27 | - | VdWContact |
| GLN 24 | NTc.Cm19 | VAL 28 | - | HBAcceptor |
| GLN 24 | NTc.Cm19 | VAL 28 | - | VdWContact |
| SER 25 | NTc.Cm18 | ILE 27 | - | VdWContact |
| SER 25 | NTc.Cm18 | VAL 28 | - | VdWContact |
| VAL 26 | NTc.Cm17 | ILE 27 | - | Hydrophobic |
| VAL 26 | NTc.Cm17 | ILE 27 | - | VdWContact |
| VAL 26 | NTc.Cm17 | VAL 28 | - | HBDonor |
| VAL 26 | NTc.Cm17 | VAL 28 | - | VdWContact |
| VAL 26 | NTc.Cm17 | VAL 29 | - | VdWContact |
| VAL 26 | NTc.Cm17 | ASP 30 | - | VdWContact |
| ASN 27 | NTc.Cm16 | ASP 30 | - | VdWContact |
| VAL 28 | NTc.Cm15 | ASP 30 | - | HBDonor |
| VAL 28 | NTc.Cm15 | ASP 30 | - | VdWContact |
| VAL 28 | NTc.Cm15 | THR 31 | - | Hydrophobic |
| VAL 28 | NTc.Cm15 | THR 31 | - | VdWContact |
| VAL 28 | NTc.Cm15 | VAL 32 | - | HBAcceptor |
| VAL 28 | NTc.Cm15 | VAL 32 | - | VdWContact |
| LYS 29 | NTc.Cm14 | VAL 32 | - | VdWContact |
| SER 30 | NTc.Cm13 | VAL 32 | - | HBDonor |
| SER 30 | NTc.Cm13 | VAL 32 | - | VdWContact |
| SER 30 | NTc.Cm13 | MET 33 | - | VdWContact |
| PRO 33 | NTc.Cm10 | MET 37 | - | Hydrophobic |
| PRO 33 | NTc.Cm10 | HIS 291 | 7.29x28 | Hydrophobic |
| PRO 33 | NTc.Cm10 | HIS 291 | 7.29x28 | VdWContact |
| PRO 33 | NTc.Cm10 | PHE 294 | 7.32x31 | Hydrophobic |
| PRO 33 | NTc.Cm10 | PHE 294 | 7.32x31 | VdWContact |
| HIS 34 | NTc.Cm9 | ARG 197 | 45.51x51 | HBAcceptor |
| HIS 34 | NTc.Cm9 | ARG 197 | 45.51x51 | VdWContact |
| HIS 34 | NTc.Cm9 | GLU 290 | 7.28x27 | HBDonor |
| HIS 34 | NTc.Cm9 | GLU 290 | 7.28x27 | Hydrophobic |
| HIS 34 | NTc.Cm9 | GLU 290 | 7.28x27 | VdWContact |
| HIS 34 | NTc.Cm9 | PHE 294 | 7.32x31 | HBDonor |
| HIS 34 | NTc.Cm9 | PHE 294 | 7.32x31 | Hydrophobic |
| HIS 34 | NTc.Cm9 | PHE 294 | 7.32x31 | PiStacking |
| HIS 34 | NTc.Cm9 | PHE 294 | 7.32x31 | VdWContact |
| CYS 35 | NTc.Cm8 | ARG 197 | 45.51x51 | VdWContact |
| ALA 36 | NTc.Cm7 | SER 188 | - | HBAcceptor |
| ALA 36 | NTc.Cm7 | SER 188 | - | VdWContact |
| ALA 36 | NTc.Cm7 | TYR 195 | - | Hydrophobic |
| ALA 36 | NTc.Cm7 | TYR 195 | - | VdWContact |
| ALA 36 | NTc.Cm7 | ARG 197 | 45.51x51 | VdWContact |
| LEU 44 | CX.4 | LEU 5 | - | Hydrophobic |
| LYS 45 | CX.5 | ASP 25 | - | Cationic |
| LYS 45 | CX.5 | ASP 25 | - | HBDonor |
| LYS 45 | CX.5 | ASP 25 | - | VdWContact |
| ARG 48 | cxb1.5 | ASP 2 | - | Cationic |
| ARG 48 | cxb1.5 | ASP 2 | - | HBDonor |
| ARG 48 | cxb1.5 | ASP 2 | - | VdWContact |
| ALA 50 | cxb1.8 | LEU 5 | - | Hydrophobic |
| ILE 58 | B1.3 | PHE 14 | - | Hydrophobic |
| ILE 58 | B1.3 | PHE 14 | - | VdWContact |
| LYS 61 | B1.6 | SER 15 | - | HBDonor |
| LYS 61 | B1.6 | SER 15 | - | VdWContact |
| ILE 62 | B1.7 | TRP 19 | - | Hydrophobic |
| ILE 62 | B1.7 | TRP 19 | - | VdWContact |
| LYS 65 | b1b2.7 | TRP 19 | - | Hydrophobic |
| LYS 65 | b1b2.7 | TRP 19 | - | VdWContact |
| MET 66 | b1b2.8 | ILE 27 | - | Hydrophobic |
| MET 66 | b1b2.8 | ILE 27 | - | VdWContact |
| MET 66 | b1b2.8 | VAL 29 | - | Hydrophobic |
| MET 66 | b1b2.8 | VAL 29 | - | VdWContact |
