Predicted complex interactions
CXCL10_HUMAN + ACKR3
SUMMARY
- Chemokine
- CXCL10_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- ACKR3 View partner entry
- Partner description
- UniProt: P25106; Gene: ackr3_human; Family: Chemokine
- Interactions detected
- 117
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| VAL 1 | NTc.Cm29 | HIS 121 | 3.29x29 | Hydrophobic |
| VAL 1 | NTc.Cm29 | PHE 124 | 3.32x32 | Hydrophobic |
| VAL 1 | NTc.Cm29 | PHE 124 | 3.32x32 | VdWContact |
| VAL 1 | NTc.Cm29 | SER 125 | 3.33x33 | VdWContact |
| VAL 1 | NTc.Cm29 | TYR 268 | 6.51x51 | HBAcceptor |
| VAL 1 | NTc.Cm29 | TYR 268 | 6.51x51 | HBDonor |
| VAL 1 | NTc.Cm29 | TYR 268 | 6.51x51 | VdWContact |
| VAL 1 | NTc.Cm29 | GLN 301 | 7.39x38 | VdWContact |
| PRO 2 | NTc.Cm28 | TRP 100 | 2.60x60 | Hydrophobic |
| PRO 2 | NTc.Cm28 | TRP 100 | 2.60x60 | VdWContact |
| PRO 2 | NTc.Cm28 | PHE 124 | 3.32x32 | Hydrophobic |
| PRO 2 | NTc.Cm28 | PHE 124 | 3.32x32 | VdWContact |
| PRO 2 | NTc.Cm28 | GLN 301 | 7.39x38 | Hydrophobic |
| PRO 2 | NTc.Cm28 | GLN 301 | 7.39x38 | VdWContact |
| SER 4 | NTc.Cm26 | CYS 196 | 45.50x50 | HBDonor |
| SER 4 | NTc.Cm26 | CYS 196 | 45.50x50 | VdWContact |
| ARG 5 | NTc.Cm25 | GLU 213 | 5.39x40 | Cationic |
| ARG 5 | NTc.Cm25 | GLU 213 | 5.39x40 | HBDonor |
| ARG 5 | NTc.Cm25 | GLU 213 | 5.39x40 | VdWContact |
| ARG 5 | NTc.Cm25 | ALA 271 | 6.54x54 | HBDonor |
| ARG 5 | NTc.Cm25 | ALA 271 | 6.54x54 | VdWContact |
| ARG 5 | NTc.Cm25 | VAL 272 | 6.55x55 | VdWContact |
| ARG 5 | NTc.Cm25 | ASP 275 | 6.58x58 | Cationic |
| ARG 5 | NTc.Cm25 | ASP 275 | 6.58x58 | HBDonor |
| ARG 5 | NTc.Cm25 | ASP 275 | 6.58x58 | VdWContact |
| ARG 5 | NTc.Cm25 | LEU 297 | 7.35x34 | Hydrophobic |
| ARG 5 | NTc.Cm25 | LEU 297 | 7.35x34 | VdWContact |
| THR 6 | NTc.Cm24 | TYR 200 | - | Hydrophobic |
| THR 6 | NTc.Cm24 | LEU 209 | 5.35x36 | Hydrophobic |
| THR 6 | NTc.Cm24 | LEU 209 | 5.35x36 | VdWContact |
| VAL 7 | NTc.Cm23 | ARG 197 | 45.51x51 | VdWContact |
| ARG 8 | NTc.Cm22 | ASP 275 | 6.58x58 | Cationic |
| ARG 8 | NTc.Cm22 | ASP 275 | 6.58x58 | VdWContact |
| ARG 8 | NTc.Cm22 | ILE 279 | 6.62x62 | Hydrophobic |
| ARG 8 | NTc.Cm22 | GLU 290 | 7.28x27 | Cationic |
| ARG 8 | NTc.Cm22 | GLU 290 | 7.28x27 | VdWContact |
| THR 10 | NTc.Cm20 | PHE 285 | - | Hydrophobic |
| ILE 12 | NTc.Cm18 | ILE 205 | 5.31x32 | Hydrophobic |
| ILE 12 | NTc.Cm18 | LYS 206 | 5.32x33 | Hydrophobic |
| ILE 12 | NTc.Cm18 | LYS 206 | 5.32x33 | VdWContact |
| ILE 12 | NTc.Cm18 | ILE 279 | 6.62x62 | Hydrophobic |
| PRO 21 | NTc.Cm9 | TRP 19 | - | Hydrophobic |
| PRO 21 | NTc.Cm9 | TRP 19 | - | VdWContact |
| PRO 21 | NTc.Cm9 | ILE 27 | - | Hydrophobic |
| PRO 21 | NTc.Cm9 | ILE 27 | - | VdWContact |
| ARG 22 | NTc.Cm8 | ASP 25 | - | Cationic |
| ARG 22 | NTc.Cm8 | ASP 25 | - | Hydrophobic |
| ARG 22 | NTc.Cm8 | ASP 25 | - | VdWContact |
| LEU 24 | NTc.Cm6 | ILE 27 | - | Hydrophobic |
| LEU 24 | NTc.Cm6 | ILE 27 | - | VdWContact |
| GLU 25 | NTc.Cm5 | VAL 28 | - | HBAcceptor |
| GLU 25 | NTc.Cm5 | VAL 28 | - | VdWContact |
| LYS 26 | NTc.Cm4 | VAL 28 | - | Hydrophobic |
| LYS 26 | NTc.Cm4 | VAL 28 | - | VdWContact |
| LYS 26 | NTc.Cm4 | ASP 30 | - | Cationic |
| LYS 26 | NTc.Cm4 | ASP 30 | - | HBDonor |
| LYS 26 | NTc.Cm4 | ASP 30 | - | VdWContact |
| LEU 27 | NTc.Cm3 | VAL 28 | - | HBDonor |
| LEU 27 | NTc.Cm3 | VAL 28 | - | VdWContact |
| LEU 27 | NTc.Cm3 | VAL 29 | - | Hydrophobic |
| LEU 27 | NTc.Cm3 | VAL 29 | - | VdWContact |
| LEU 27 | NTc.Cm3 | ASP 30 | - | HBAcceptor |
| LEU 27 | NTc.Cm3 | ASP 30 | - | VdWContact |
| GLU 28 | NTc.Cm2 | ASP 30 | - | Hydrophobic |
| GLU 28 | NTc.Cm2 | ASP 30 | - | VdWContact |
| GLU 28 | NTc.Cm2 | VAL 32 | - | Hydrophobic |
| ILE 29 | NTc.Cm1 | PHE 6 | - | Hydrophobic |
| ILE 29 | NTc.Cm1 | VAL 29 | - | Hydrophobic |
| ILE 29 | NTc.Cm1 | ASP 30 | - | HBDonor |
| ILE 29 | NTc.Cm1 | ASP 30 | - | VdWContact |
| ILE 29 | NTc.Cm1 | THR 31 | - | Hydrophobic |
| ILE 29 | NTc.Cm1 | VAL 32 | - | HBAcceptor |
| ILE 29 | NTc.Cm1 | VAL 32 | - | VdWContact |
| ILE 30 | CX.1 | VAL 32 | - | Hydrophobic |
| ILE 30 | CX.1 | PHE 285 | - | Hydrophobic |
| PRO 31 | CX.4 | VAL 32 | - | VdWContact |
| PRO 31 | CX.4 | MET 33 | - | Hydrophobic |
| PRO 31 | CX.4 | MET 33 | - | VdWContact |
| SER 33 | cxb1.1 | ARG 197 | 45.51x51 | HBAcceptor |
| SER 33 | cxb1.1 | ARG 197 | 45.51x51 | VdWContact |
| GLN 34 | cxb1.2 | LYS 40 | - | HBAcceptor |
| GLN 34 | cxb1.2 | LYS 40 | - | VdWContact |
| GLN 34 | cxb1.2 | TYR 195 | - | Hydrophobic |
| GLN 34 | cxb1.2 | ARG 197 | 45.51x51 | HBAcceptor |
| PHE 35 | cxb1.5 | GLU 290 | 7.28x27 | Hydrophobic |
| PHE 35 | cxb1.5 | PHE 294 | 7.32x31 | Hydrophobic |
| PHE 35 | cxb1.5 | PHE 294 | 7.32x31 | VdWContact |
| PRO 37 | cxb1.7 | VAL 186 | - | Hydrophobic |
| PRO 37 | cxb1.7 | ARG 197 | 45.51x51 | VdWContact |
| ARG 38 | cxb1.8 | ILE 205 | 5.31x32 | VdWContact |
| VAL 39 | cxb1.10 | PHE 6 | - | Hydrophobic |
| LYS 46 | B1.3 | ASP 25 | - | Cationic |
| LYS 46 | B1.3 | ASP 25 | - | HBDonor |
| LYS 46 | B1.3 | ASP 25 | - | VdWContact |
| LYS 46 | B1.3 | CYS 26 | - | HBDonor |
| LYS 46 | B1.3 | CYS 26 | - | VdWContact |
| LYS 62 | B2.2 | MET 1 | - | Hydrophobic |
| LYS 62 | B2.2 | MET 1 | - | VdWContact |
| LEU 64 | B2.4 | TRP 19 | - | Hydrophobic |
| LEU 64 | B2.4 | TRP 19 | - | VdWContact |
| LEU 65 | B2.5 | PHE 6 | - | Hydrophobic |
| LEU 65 | B2.5 | PHE 6 | - | VdWContact |
| LYS 66 | B2.6 | LEU 5 | - | Hydrophobic |
| LYS 66 | B2.6 | LEU 5 | - | VdWContact |
| ALA 67 | b2b3.2 | TRP 19 | - | Hydrophobic |
| ALA 67 | b2b3.2 | TRP 19 | - | VdWContact |
| VAL 68 | b2b3.3 | ILE 17 | - | Hydrophobic |
| VAL 68 | b2b3.3 | TRP 19 | - | Hydrophobic |
| VAL 68 | b2b3.3 | VAL 29 | - | Hydrophobic |
| VAL 68 | b2b3.3 | VAL 29 | - | VdWContact |
| SER 69 | b2b3.4 | TYR 8 | - | VdWContact |
| GLU 71 | b2b3.12 | ILE 17 | - | Hydrophobic |
| ARG 72 | B3.1 | GLY 12 | - | VdWContact |
| ARG 72 | B3.1 | PHE 14 | - | VdWContact |
| ARG 75 | B3.4 | ASP 16 | - | VdWContact |
| ARG 75 | B3.4 | SER 18 | - | HBDonor |
| ARG 75 | B3.4 | SER 18 | - | VdWContact |
