Predicted complex interactions
CXCL17_HUMAN + ACKR3
SUMMARY
- Chemokine
- CXCL17_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- ACKR3 View partner entry
- Partner description
- UniProt: P25106; Gene: ackr3_human; Family: Chemokine
- Interactions detected
- 134
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| LEU 22 | NTc.Cm28 | ASP 16 | - | VdWContact |
| GLY 26 | NTc.Cm24 | ASP 30 | - | HBDonor |
| GLY 26 | NTc.Cm24 | ASP 30 | - | VdWContact |
| GLU 28 | NTc.Cm22 | PHE 14 | - | Hydrophobic |
| GLU 28 | NTc.Cm22 | PHE 14 | - | VdWContact |
| GLU 28 | NTc.Cm22 | ASP 30 | - | Hydrophobic |
| GLU 28 | NTc.Cm22 | ASP 30 | - | VdWContact |
| GLU 28 | NTc.Cm22 | THR 31 | - | VdWContact |
| GLU 28 | NTc.Cm22 | VAL 32 | - | Hydrophobic |
| GLU 28 | NTc.Cm22 | VAL 32 | - | VdWContact |
| CYS 29 | NTc.Cm21 | VAL 29 | - | Hydrophobic |
| CYS 29 | NTc.Cm21 | ASP 30 | - | HBDonor |
| CYS 29 | NTc.Cm21 | ASP 30 | - | VdWContact |
| CYS 29 | NTc.Cm21 | THR 31 | - | Hydrophobic |
| CYS 29 | NTc.Cm21 | THR 31 | - | VdWContact |
| GLU 30 | NTc.Cm20 | VAL 32 | - | Hydrophobic |
| GLU 30 | NTc.Cm20 | VAL 32 | - | VdWContact |
| GLU 30 | NTc.Cm20 | PHE 285 | - | Hydrophobic |
| GLU 30 | NTc.Cm20 | PHE 285 | - | VdWContact |
| LYS 32 | NTc.Cm18 | SER 278 | 6.61x61 | VdWContact |
| LYS 32 | NTc.Cm18 | PHE 285 | - | Hydrophobic |
| LYS 32 | NTc.Cm18 | PHE 285 | - | VdWContact |
| LYS 32 | NTc.Cm18 | THR 286 | 7.24x23 | HBDonor |
| LYS 32 | NTc.Cm18 | THR 286 | 7.24x23 | VdWContact |
| LYS 32 | NTc.Cm18 | LEU 289 | 7.27x26 | VdWContact |
| LYS 32 | NTc.Cm18 | GLU 290 | 7.28x27 | HBDonor |
| LYS 32 | NTc.Cm18 | GLU 290 | 7.28x27 | VdWContact |
| TRP 34 | NTc.Cm16 | ILE 205 | 5.31x32 | Hydrophobic |
| TRP 34 | NTc.Cm16 | ILE 205 | 5.31x32 | VdWContact |
| PHE 35 | NTc.Cm15 | LYS 206 | 5.32x33 | VdWContact |
| PHE 35 | NTc.Cm15 | LEU 209 | 5.35x36 | Hydrophobic |
| PHE 35 | NTc.Cm15 | LEU 209 | 5.35x36 | VdWContact |
| PHE 35 | NTc.Cm15 | ILE 279 | 6.62x62 | Hydrophobic |
| LEU 36 | NTc.Cm14 | LYS 206 | 5.32x33 | HBAcceptor |
| LEU 36 | NTc.Cm14 | LYS 206 | 5.32x33 | VdWContact |
| LEU 36 | NTc.Cm14 | SER 278 | 6.61x61 | VdWContact |
| LEU 36 | NTc.Cm14 | ILE 279 | 6.62x62 | VdWContact |
| LEU 36 | NTc.Cm14 | HIS 281 | 6.64x64 | Hydrophobic |
| LEU 36 | NTc.Cm14 | HIS 281 | 6.64x64 | VdWContact |
| ALA 38 | NTc.Cm12 | ILE 205 | 5.31x32 | Hydrophobic |
| ALA 38 | NTc.Cm12 | LYS 206 | 5.32x33 | Hydrophobic |
| ALA 38 | NTc.Cm12 | LYS 206 | 5.32x33 | VdWContact |
| ARG 40 | NTc.Cm10 | HIS 281 | 6.64x64 | HBDonor |
| ARG 40 | NTc.Cm10 | HIS 281 | 6.64x64 | VdWContact |
| PRO 50 | CX.1 | CYS 26 | - | VdWContact |
| PRO 50 | CX.1 | ILE 27 | - | VdWContact |
| PRO 50 | CX.1 | VAL 28 | - | Hydrophobic |
| PRO 50 | CX.1 | VAL 28 | - | VdWContact |
| LYS 51 | CX.4 | ILE 27 | - | Hydrophobic |
| LYS 51 | CX.4 | ILE 27 | - | VdWContact |
| LYS 51 | CX.4 | VAL 28 | - | VdWContact |
| LYS 52 | CX.5 | VAL 28 | - | Hydrophobic |
| LYS 52 | CX.5 | VAL 28 | - | VdWContact |
| LYS 52 | CX.5 | ASP 30 | - | Cationic |
| LYS 52 | CX.5 | ASP 30 | - | HBDonor |
| LYS 52 | CX.5 | ASP 30 | - | VdWContact |
| GLN 53 | cxb1.1 | ILE 27 | - | HBDonor |
| GLN 53 | cxb1.1 | ILE 27 | - | Hydrophobic |
| GLN 53 | cxb1.1 | ILE 27 | - | VdWContact |
| GLN 53 | cxb1.1 | VAL 29 | - | Hydrophobic |
| GLN 53 | cxb1.1 | VAL 29 | - | VdWContact |
| PRO 55 | cxb1.5 | VAL 29 | - | Hydrophobic |
| PRO 55 | cxb1.5 | VAL 29 | - | VdWContact |
| HIS 58 | cxb1.10 | ILE 27 | - | Hydrophobic |
| PHE 59 | cxb1.11 | GLU 202 | - | Hydrophobic |
| PHE 59 | cxb1.11 | GLU 202 | - | VdWContact |
| LYS 77 | b1b2.12 | PRO 20 | - | HBDonor |
| LYS 77 | b1b2.12 | PRO 20 | - | VdWContact |
| LYS 77 | b1b2.12 | ASN 22 | - | HBDonor |
| LYS 77 | b1b2.12 | ASN 22 | - | VdWContact |
| ARG 80 | b1b2.16 | TRP 19 | - | Hydrophobic |
| ALA 81 | b1b2.17 | TRP 19 | - | Hydrophobic |
| ALA 81 | b1b2.17 | TRP 19 | - | VdWContact |
| GLN 83 | b1b2.19 | PHE 199 | - | Hydrophobic |
| GLN 83 | b1b2.19 | PHE 199 | - | VdWContact |
| GLN 83 | b1b2.19 | GLU 202 | - | HBDonor |
| GLN 83 | b1b2.19 | GLU 202 | - | VdWContact |
| GLN 84 | b1b2.20 | TRP 19 | - | Hydrophobic |
| GLN 84 | b1b2.20 | TRP 19 | - | VdWContact |
| GLN 84 | b1b2.20 | ALA 189 | - | VdWContact |
| LEU 86 | b1b2.22 | PHE 199 | - | Hydrophobic |
| LEU 86 | b1b2.22 | PHE 199 | - | VdWContact |
| LEU 86 | b1b2.22 | GLU 202 | - | Hydrophobic |
| LEU 86 | b1b2.22 | ILE 205 | 5.31x32 | Hydrophobic |
| LYS 87 | b1b2.23 | VAL 186 | - | VdWContact |
| LYS 87 | b1b2.23 | THR 187 | - | HBDonor |
| LYS 87 | b1b2.23 | THR 187 | - | VdWContact |
| LYS 87 | b1b2.23 | ARG 197 | 45.51x51 | VdWContact |
| GLN 88 | b1b2.24 | MET 33 | - | VdWContact |
| GLN 90 | B2.1 | ARG 197 | 45.51x51 | VdWContact |
| GLN 90 | B2.1 | SER 198 | 45.52x52 | HBDonor |
| GLN 90 | B2.1 | SER 198 | 45.52x52 | VdWContact |
| LEU 91 | B2.2 | TYR 195 | - | Hydrophobic |
| LEU 91 | B2.2 | TYR 195 | - | VdWContact |
| LEU 91 | B2.2 | ARG 197 | 45.51x51 | HBAcceptor |
| LEU 91 | B2.2 | ARG 197 | 45.51x51 | VdWContact |
| ARG 92 | B2.3 | VAL 32 | - | HBDonor |
| ARG 92 | B2.3 | VAL 32 | - | VdWContact |
| ARG 92 | B2.3 | CYS 34 | - | Cationic |
| ARG 92 | B2.3 | GLU 290 | 7.28x27 | Cationic |
| ARG 92 | B2.3 | GLU 290 | 7.28x27 | HBDonor |
| ARG 92 | B2.3 | GLU 290 | 7.28x27 | VdWContact |
| SER 93 | B2.4 | ASP 275 | 6.58x58 | HBDonor |
| SER 93 | B2.4 | ASP 275 | 6.58x58 | VdWContact |
| PHE 94 | B2.5 | ASP 275 | 6.58x58 | Hydrophobic |
| PHE 94 | B2.5 | ASP 275 | 6.58x58 | VdWContact |
| PHE 94 | B2.5 | GLU 290 | 7.28x27 | Hydrophobic |
| PHE 94 | B2.5 | GLU 290 | 7.28x27 | VdWContact |
| PHE 94 | B2.5 | LEU 293 | 7.31x30 | Hydrophobic |
| PHE 94 | B2.5 | LEU 293 | 7.31x30 | VdWContact |
| PHE 94 | B2.5 | PHE 294 | 7.32x31 | Hydrophobic |
| PHE 94 | B2.5 | PHE 294 | 7.32x31 | VdWContact |
| PHE 94 | B2.5 | LEU 297 | 7.35x34 | Hydrophobic |
| PHE 94 | B2.5 | LEU 297 | 7.35x34 | VdWContact |
| ALA 95 | B2.6 | ARG 197 | 45.51x51 | VdWContact |
| LEU 96 | b2b3.2 | LEU 209 | 5.35x36 | Hydrophobic |
| LEU 96 | b2b3.2 | GLU 213 | 5.39x40 | Hydrophobic |
| PRO 97 | b2b3.3 | TYR 268 | 6.51x51 | Hydrophobic |
| PRO 97 | b2b3.3 | TYR 268 | 6.51x51 | VdWContact |
| PRO 97 | b2b3.3 | LEU 297 | 7.35x34 | Hydrophobic |
| PRO 97 | b2b3.3 | LEU 297 | 7.35x34 | VdWContact |
| PRO 97 | b2b3.3 | GLN 301 | 7.39x38 | Hydrophobic |
| PRO 97 | b2b3.3 | GLN 301 | 7.39x38 | VdWContact |
| LEU 98 | b2b3.4 | TRP 100 | 2.60x60 | Hydrophobic |
| LEU 98 | b2b3.4 | TRP 100 | 2.60x60 | VdWContact |
| LEU 98 | b2b3.4 | HIS 121 | 3.29x29 | Hydrophobic |
| LEU 98 | b2b3.4 | HIS 121 | 3.29x29 | VdWContact |
| LEU 98 | b2b3.4 | PHE 124 | 3.32x32 | Hydrophobic |
| LEU 98 | b2b3.4 | PHE 124 | 3.32x32 | VdWContact |
| LEU 98 | b2b3.4 | SER 125 | 3.33x33 | HBAcceptor |
| LEU 98 | b2b3.4 | SER 125 | 3.33x33 | VdWContact |
| LEU 98 | b2b3.4 | TYR 268 | 6.51x51 | HBAcceptor |
| LEU 98 | b2b3.4 | TYR 268 | 6.51x51 | VdWContact |
| LEU 98 | b2b3.4 | GLN 301 | 7.39x38 | VdWContact |
