Predicted complex interactions
CXCL5_HUMAN + ACKR3
SUMMARY
- Chemokine
- CXCL5_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- ACKR3 View partner entry
- Partner description
- UniProt: P25106; Gene: ackr3_human; Family: Chemokine
- Interactions detected
- 127
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ALA 1 | NTc.Cm48 | GLU 213 | 5.39x40 | Hydrophobic |
| ALA 1 | NTc.Cm48 | GLU 213 | 5.39x40 | VdWContact |
| ALA 1 | NTc.Cm48 | VAL 272 | 6.55x55 | Hydrophobic |
| ALA 1 | NTc.Cm48 | VAL 272 | 6.55x55 | VdWContact |
| ALA 1 | NTc.Cm48 | ASP 275 | 6.58x58 | Cationic |
| ALA 1 | NTc.Cm48 | ASP 275 | 6.58x58 | HBDonor |
| ALA 1 | NTc.Cm48 | ASP 275 | 6.58x58 | Hydrophobic |
| ALA 1 | NTc.Cm48 | ASP 275 | 6.58x58 | VdWContact |
| ALA 1 | NTc.Cm48 | LEU 297 | 7.35x34 | VdWContact |
| GLY 2 | NTc.Cm47 | TYR 268 | 6.51x51 | VdWContact |
| PRO 3 | NTc.Cm46 | TRP 100 | 2.60x60 | Hydrophobic |
| PRO 3 | NTc.Cm46 | HIS 121 | 3.29x29 | VdWContact |
| PRO 3 | NTc.Cm46 | PHE 124 | 3.32x32 | Hydrophobic |
| PRO 3 | NTc.Cm46 | PHE 124 | 3.32x32 | VdWContact |
| PRO 3 | NTc.Cm46 | TYR 268 | 6.51x51 | Hydrophobic |
| PRO 3 | NTc.Cm46 | TYR 268 | 6.51x51 | VdWContact |
| PRO 3 | NTc.Cm46 | GLN 301 | 7.39x38 | Hydrophobic |
| PRO 3 | NTc.Cm46 | GLN 301 | 7.39x38 | VdWContact |
| ALA 4 | NTc.Cm45 | HIS 121 | 3.29x29 | VdWContact |
| ALA 4 | NTc.Cm45 | ASP 179 | 4.60x61 | VdWContact |
| ALA 5 | NTc.Cm44 | GLU 213 | 5.39x40 | Hydrophobic |
| ALA 5 | NTc.Cm44 | GLU 213 | 5.39x40 | VdWContact |
| ALA 6 | NTc.Cm43 | LEU 297 | 7.35x34 | Hydrophobic |
| ALA 6 | NTc.Cm43 | LEU 297 | 7.35x34 | VdWContact |
| ALA 6 | NTc.Cm43 | GLN 301 | 7.39x38 | VdWContact |
| VAL 7 | NTc.Cm42 | TRP 100 | 2.60x60 | Hydrophobic |
| VAL 7 | NTc.Cm42 | TRP 100 | 2.60x60 | VdWContact |
| VAL 7 | NTc.Cm42 | HIS 121 | 3.29x29 | Hydrophobic |
| LEU 8 | NTc.Cm41 | ASP 179 | 4.60x61 | VdWContact |
| LEU 8 | NTc.Cm41 | LEU 183 | 4.64x65 | Hydrophobic |
| LEU 8 | NTc.Cm41 | SER 198 | 45.52x52 | VdWContact |
| LEU 8 | NTc.Cm41 | TYR 200 | - | VdWContact |
| ARG 9 | NTc.Cm40 | LEU 209 | 5.35x36 | VdWContact |
| ARG 9 | NTc.Cm40 | GLU 213 | 5.39x40 | Cationic |
| ARG 9 | NTc.Cm40 | GLU 213 | 5.39x40 | HBDonor |
| ARG 9 | NTc.Cm40 | GLU 213 | 5.39x40 | VdWContact |
| ARG 9 | NTc.Cm40 | ASP 275 | 6.58x58 | Cationic |
| ARG 9 | NTc.Cm40 | ASP 275 | 6.58x58 | HBDonor |
| ARG 9 | NTc.Cm40 | ASP 275 | 6.58x58 | VdWContact |
| ARG 9 | NTc.Cm40 | ILE 276 | 6.59x59 | VdWContact |
| ARG 9 | NTc.Cm40 | ILE 279 | 6.62x62 | VdWContact |
| GLU 10 | NTc.Cm39 | LYS 40 | - | Anionic |
| GLU 10 | NTc.Cm39 | LYS 40 | - | HBAcceptor |
| GLU 10 | NTc.Cm39 | LYS 40 | - | VdWContact |
| GLU 10 | NTc.Cm39 | ASN 108 | - | HBAcceptor |
| GLU 10 | NTc.Cm39 | ASN 108 | - | VdWContact |
| GLU 10 | NTc.Cm39 | ARG 197 | 45.51x51 | Anionic |
| GLU 10 | NTc.Cm39 | ARG 197 | 45.51x51 | HBAcceptor |
| GLU 10 | NTc.Cm39 | ARG 197 | 45.51x51 | VdWContact |
| GLU 10 | NTc.Cm39 | PHE 294 | 7.32x31 | Hydrophobic |
| GLU 10 | NTc.Cm39 | PHE 294 | 7.32x31 | VdWContact |
| GLU 10 | NTc.Cm39 | HIS 298 | 7.36x35 | Hydrophobic |
| LEU 11 | NTc.Cm38 | LEU 183 | 4.64x65 | Hydrophobic |
| LEU 11 | NTc.Cm38 | CYS 196 | 45.50x50 | VdWContact |
| LEU 11 | NTc.Cm38 | ARG 197 | 45.51x51 | HBAcceptor |
| LEU 11 | NTc.Cm38 | ARG 197 | 45.51x51 | Hydrophobic |
| LEU 11 | NTc.Cm38 | ARG 197 | 45.51x51 | VdWContact |
| LEU 11 | NTc.Cm38 | SER 198 | 45.52x52 | VdWContact |
| ARG 12 | NTc.Cm37 | TYR 200 | - | Hydrophobic |
| ARG 12 | NTc.Cm37 | TYR 200 | - | VdWContact |
| ARG 12 | NTc.Cm37 | LEU 209 | 5.35x36 | VdWContact |
| ARG 12 | NTc.Cm37 | GLU 213 | 5.39x40 | Cationic |
| ARG 12 | NTc.Cm37 | GLU 213 | 5.39x40 | HBDonor |
| ARG 12 | NTc.Cm37 | GLU 213 | 5.39x40 | VdWContact |
| CYS 13 | NTc.Cm36 | ARG 197 | 45.51x51 | Anionic |
| CYS 13 | NTc.Cm36 | ARG 197 | 45.51x51 | VdWContact |
| VAL 14 | NTc.Cm35 | ILE 205 | 5.31x32 | VdWContact |
| LEU 16 | NTc.Cm33 | PHE 199 | - | Hydrophobic |
| LEU 16 | NTc.Cm33 | PHE 199 | - | VdWContact |
| LEU 16 | NTc.Cm33 | TYR 200 | - | VdWContact |
| LEU 16 | NTc.Cm33 | GLU 202 | - | Hydrophobic |
| LEU 16 | NTc.Cm33 | ILE 205 | 5.31x32 | Hydrophobic |
| GLN 17 | NTc.Cm32 | GLU 202 | - | HBDonor |
| GLN 17 | NTc.Cm32 | GLU 202 | - | VdWContact |
| PRO 24 | NTc.Cm25 | ILE 27 | - | Hydrophobic |
| PRO 24 | NTc.Cm25 | ILE 27 | - | VdWContact |
| LYS 25 | NTc.Cm24 | ASP 25 | - | Hydrophobic |
| ILE 27 | NTc.Cm22 | ILE 27 | - | Hydrophobic |
| LEU 30 | NTc.Cm19 | ILE 27 | - | Hydrophobic |
| LEU 30 | NTc.Cm19 | VAL 29 | - | Hydrophobic |
| LEU 30 | NTc.Cm19 | VAL 29 | - | VdWContact |
| GLN 31 | NTc.Cm18 | PHE 6 | - | Hydrophobic |
| VAL 32 | NTc.Cm17 | ASP 30 | - | VdWContact |
| VAL 32 | NTc.Cm17 | THR 31 | - | Hydrophobic |
| VAL 32 | NTc.Cm17 | THR 31 | - | VdWContact |
| ALA 34 | NTc.Cm15 | VAL 32 | - | VdWContact |
| ALA 34 | NTc.Cm15 | MET 33 | - | VdWContact |
| ALA 34 | NTc.Cm15 | CYS 34 | - | Hydrophobic |
| ALA 34 | NTc.Cm15 | CYS 34 | - | VdWContact |
| PRO 37 | NTc.Cm12 | GLU 290 | 7.28x27 | Hydrophobic |
| PRO 37 | NTc.Cm12 | HIS 291 | 7.29x28 | Hydrophobic |
| PRO 37 | NTc.Cm12 | PHE 294 | 7.32x31 | Hydrophobic |
| PRO 37 | NTc.Cm12 | PHE 294 | 7.32x31 | VdWContact |
| GLN 38 | NTc.Cm11 | ARG 197 | 45.51x51 | HBAcceptor |
| GLN 38 | NTc.Cm11 | ARG 197 | 45.51x51 | VdWContact |
| GLN 38 | NTc.Cm11 | GLU 290 | 7.28x27 | HBDonor |
| GLN 38 | NTc.Cm11 | GLU 290 | 7.28x27 | VdWContact |
| CYS 39 | NTc.Cm10 | ARG 197 | 45.51x51 | Anionic |
| CYS 39 | NTc.Cm10 | ARG 197 | 45.51x51 | VdWContact |
| SER 40 | NTc.Cm9 | TYR 195 | - | VdWContact |
| SER 40 | NTc.Cm9 | ARG 197 | 45.51x51 | VdWContact |
| LYS 41 | NTc.Cm8 | THR 187 | - | HBDonor |
| LYS 41 | NTc.Cm8 | THR 187 | - | VdWContact |
| LYS 41 | NTc.Cm8 | SER 188 | - | VdWContact |
| VAL 42 | NTc.Cm7 | MET 33 | - | Hydrophobic |
| LYS 49 | CX.1 | ASP 25 | - | Cationic |
| LYS 49 | CX.1 | ASP 25 | - | HBDonor |
| LYS 49 | CX.1 | ASP 25 | - | VdWContact |
| GLU 53 | cxb1.2 | LYS 206 | 5.32x33 | Anionic |
| PHE 62 | B1.1 | TRP 19 | - | Hydrophobic |
| PHE 62 | B1.1 | TRP 19 | - | VdWContact |
| LYS 65 | B1.4 | TRP 19 | - | Hydrophobic |
| LYS 65 | B1.4 | TRP 19 | - | VdWContact |
| VAL 66 | B1.5 | TRP 19 | - | Hydrophobic |
| VAL 66 | B1.5 | TRP 19 | - | VdWContact |
| VAL 66 | B1.5 | VAL 29 | - | Hydrophobic |
| LYS 69 | b1b2.4 | ILE 17 | - | Hydrophobic |
| LYS 69 | b1b2.4 | ILE 17 | - | VdWContact |
| ILE 70 | b1b2.6 | ILE 17 | - | Hydrophobic |
| ILE 70 | b1b2.6 | ILE 17 | - | VdWContact |
| ILE 70 | b1b2.6 | VAL 29 | - | Hydrophobic |
| ILE 70 | b1b2.6 | THR 31 | - | Hydrophobic |
| ILE 70 | b1b2.6 | THR 31 | - | VdWContact |
| ILE 70 | b1b2.6 | MET 33 | - | Hydrophobic |
| LEU 71 | b1b2.7 | MET 33 | - | Hydrophobic |
| GLU 77 | b1b2.14 | ASN 13 | - | HBAcceptor |
| GLU 77 | b1b2.14 | ASN 13 | - | VdWContact |
