Predicted complex interactions
CXCL6_HUMAN + ACKR3
SUMMARY
- Chemokine
- CXCL6_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- ACKR3 View partner entry
- Partner description
- UniProt: P25106; Gene: ackr3_human; Family: Chemokine
- Interactions detected
- 113
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLY 1 | NTc.Cm48 | ASP 179 | 4.60x61 | Cationic |
| GLY 1 | NTc.Cm48 | MET 212 | 5.38x39 | HBDonor |
| GLY 1 | NTc.Cm48 | MET 212 | 5.38x39 | VdWContact |
| GLY 1 | NTc.Cm48 | SER 216 | 5.42x43 | VdWContact |
| GLY 1 | NTc.Cm48 | TYR 268 | 6.51x51 | HBAcceptor |
| GLY 1 | NTc.Cm48 | TYR 268 | 6.51x51 | VdWContact |
| PRO 2 | NTc.Cm47 | PHE 124 | 3.32x32 | Hydrophobic |
| PRO 2 | NTc.Cm47 | PHE 124 | 3.32x32 | VdWContact |
| PRO 2 | NTc.Cm47 | LEU 128 | 3.36x36 | Hydrophobic |
| PRO 2 | NTc.Cm47 | LEU 128 | 3.36x36 | VdWContact |
| PRO 2 | NTc.Cm47 | TYR 268 | 6.51x51 | VdWContact |
| VAL 3 | NTc.Cm46 | HIS 121 | 3.29x29 | Hydrophobic |
| VAL 3 | NTc.Cm46 | HIS 121 | 3.29x29 | VdWContact |
| SER 4 | NTc.Cm45 | TYR 268 | 6.51x51 | HBDonor |
| ALA 5 | NTc.Cm44 | LEU 297 | 7.35x34 | Hydrophobic |
| ALA 5 | NTc.Cm44 | HIS 298 | 7.36x35 | Hydrophobic |
| ALA 5 | NTc.Cm44 | HIS 298 | 7.36x35 | VdWContact |
| ALA 5 | NTc.Cm44 | GLN 301 | 7.39x38 | VdWContact |
| VAL 6 | NTc.Cm43 | TRP 100 | 2.60x60 | Hydrophobic |
| VAL 6 | NTc.Cm43 | ARG 197 | 45.51x51 | HBAcceptor |
| VAL 6 | NTc.Cm43 | ARG 197 | 45.51x51 | VdWContact |
| LEU 7 | NTc.Cm42 | ARG 197 | 45.51x51 | HBAcceptor |
| LEU 7 | NTc.Cm42 | ARG 197 | 45.51x51 | VdWContact |
| LEU 7 | NTc.Cm42 | SER 198 | 45.52x52 | VdWContact |
| THR 8 | NTc.Cm41 | LEU 297 | 7.35x34 | Hydrophobic |
| THR 8 | NTc.Cm41 | LEU 297 | 7.35x34 | VdWContact |
| GLU 9 | NTc.Cm40 | LYS 40 | - | Anionic |
| GLU 9 | NTc.Cm40 | LYS 40 | - | HBAcceptor |
| GLU 9 | NTc.Cm40 | LYS 40 | - | VdWContact |
| GLU 9 | NTc.Cm40 | ASN 108 | - | HBAcceptor |
| GLU 9 | NTc.Cm40 | ASN 108 | - | VdWContact |
| GLU 9 | NTc.Cm40 | ARG 197 | 45.51x51 | Anionic |
| GLU 9 | NTc.Cm40 | ARG 197 | 45.51x51 | VdWContact |
| GLU 9 | NTc.Cm40 | PHE 294 | 7.32x31 | Hydrophobic |
| GLU 9 | NTc.Cm40 | PHE 294 | 7.32x31 | VdWContact |
| LEU 10 | NTc.Cm39 | TYR 195 | - | Hydrophobic |
| LEU 10 | NTc.Cm39 | TYR 195 | - | VdWContact |
| LEU 10 | NTc.Cm39 | ARG 197 | 45.51x51 | HBAcceptor |
| LEU 10 | NTc.Cm39 | ARG 197 | 45.51x51 | VdWContact |
| ARG 11 | NTc.Cm38 | GLU 213 | 5.39x40 | Cationic |
| ARG 11 | NTc.Cm38 | ASP 275 | 6.58x58 | Cationic |
| ARG 11 | NTc.Cm38 | ASP 275 | 6.58x58 | HBDonor |
| ARG 11 | NTc.Cm38 | ASP 275 | 6.58x58 | VdWContact |
| ARG 11 | NTc.Cm38 | ILE 279 | 6.62x62 | VdWContact |
| THR 13 | NTc.Cm36 | HIS 281 | 6.64x64 | Hydrophobic |
| THR 13 | NTc.Cm36 | PHE 285 | - | Hydrophobic |
| LEU 15 | NTc.Cm34 | ILE 205 | 5.31x32 | Hydrophobic |
| LEU 15 | NTc.Cm34 | ILE 205 | 5.31x32 | VdWContact |
| LEU 15 | NTc.Cm34 | LYS 206 | 5.32x33 | Hydrophobic |
| LEU 15 | NTc.Cm34 | LEU 209 | 5.35x36 | Hydrophobic |
| LEU 15 | NTc.Cm34 | ILE 279 | 6.62x62 | Hydrophobic |
| LEU 15 | NTc.Cm34 | ILE 279 | 6.62x62 | VdWContact |
| ARG 16 | NTc.Cm33 | GLU 207 | 5.33x34 | Cationic |
| ARG 16 | NTc.Cm33 | GLU 207 | 5.33x34 | HBDonor |
| PRO 23 | NTc.Cm26 | ILE 27 | - | Hydrophobic |
| ILE 26 | NTc.Cm23 | ILE 27 | - | Hydrophobic |
| GLY 27 | NTc.Cm22 | VAL 28 | - | HBAcceptor |
| GLY 27 | NTc.Cm22 | VAL 28 | - | VdWContact |
| LYS 28 | NTc.Cm21 | VAL 28 | - | VdWContact |
| LYS 28 | NTc.Cm21 | ASP 30 | - | Cationic |
| LYS 28 | NTc.Cm21 | ASP 30 | - | VdWContact |
| LEU 29 | NTc.Cm20 | ILE 27 | - | Hydrophobic |
| LEU 29 | NTc.Cm20 | VAL 28 | - | HBDonor |
| LEU 29 | NTc.Cm20 | VAL 28 | - | VdWContact |
| LEU 29 | NTc.Cm20 | VAL 29 | - | Hydrophobic |
| LEU 29 | NTc.Cm20 | VAL 29 | - | VdWContact |
| LEU 29 | NTc.Cm20 | ASP 30 | - | HBAcceptor |
| LEU 29 | NTc.Cm20 | ASP 30 | - | VdWContact |
| GLN 30 | NTc.Cm19 | ASP 30 | - | VdWContact |
| GLN 30 | NTc.Cm19 | VAL 32 | - | Hydrophobic |
| GLN 30 | NTc.Cm19 | VAL 32 | - | VdWContact |
| VAL 31 | NTc.Cm18 | VAL 29 | - | Hydrophobic |
| VAL 31 | NTc.Cm18 | ASP 30 | - | HBDonor |
| VAL 31 | NTc.Cm18 | ASP 30 | - | VdWContact |
| VAL 31 | NTc.Cm18 | THR 31 | - | Hydrophobic |
| VAL 31 | NTc.Cm18 | VAL 32 | - | HBAcceptor |
| VAL 31 | NTc.Cm18 | VAL 32 | - | VdWContact |
| PHE 32 | NTc.Cm17 | VAL 32 | - | Hydrophobic |
| PHE 32 | NTc.Cm17 | VAL 32 | - | VdWContact |
| PHE 32 | NTc.Cm17 | PHE 285 | - | Hydrophobic |
| PHE 32 | NTc.Cm17 | PHE 285 | - | VdWContact |
| PRO 33 | NTc.Cm16 | MET 33 | - | Hydrophobic |
| GLN 37 | NTc.Cm12 | GLU 290 | 7.28x27 | HBDonor |
| GLN 37 | NTc.Cm12 | GLU 290 | 7.28x27 | VdWContact |
| LYS 40 | NTc.Cm9 | GLU 202 | - | Cationic |
| LYS 40 | NTc.Cm9 | GLU 202 | - | HBDonor |
| LYS 40 | NTc.Cm9 | GLU 202 | - | VdWContact |
| VAL 41 | NTc.Cm8 | PHE 6 | - | Hydrophobic |
| LYS 48 | NTc.Cm1 | ASP 25 | - | Cationic |
| LYS 48 | NTc.Cm1 | ASP 25 | - | HBDonor |
| LYS 48 | NTc.Cm1 | ASP 25 | - | VdWContact |
| GLN 52 | cxb1.1 | HIS 281 | 6.64x64 | Hydrophobic |
| GLN 52 | cxb1.1 | PRO 284 | - | VdWContact |
| GLN 52 | cxb1.1 | PHE 285 | - | HBAcceptor |
| GLN 52 | cxb1.1 | PHE 285 | - | VdWContact |
| VAL 65 | B1.4 | TRP 19 | - | Hydrophobic |
| VAL 65 | B1.4 | TRP 19 | - | VdWContact |
| VAL 65 | B1.4 | VAL 29 | - | Hydrophobic |
| VAL 65 | B1.4 | VAL 29 | - | VdWContact |
| ILE 66 | B1.5 | PHE 6 | - | Hydrophobic |
| ILE 66 | B1.5 | PHE 6 | - | VdWContact |
| LYS 68 | B1.7 | TRP 19 | - | Hydrophobic |
| LYS 68 | B1.7 | PRO 20 | - | VdWContact |
| ILE 69 | b1b2.4 | PHE 14 | - | Hydrophobic |
| ILE 69 | b1b2.4 | ILE 17 | - | Hydrophobic |
| ILE 69 | b1b2.4 | ILE 17 | - | VdWContact |
| ILE 69 | b1b2.4 | VAL 29 | - | Hydrophobic |
| ILE 69 | b1b2.4 | VAL 29 | - | VdWContact |
| LEU 70 | b1b2.6 | LEU 5 | - | Hydrophobic |
| LEU 70 | b1b2.6 | TYR 8 | - | Hydrophobic |
| LEU 70 | b1b2.6 | TYR 8 | - | VdWContact |
| LYS 76 | b1b2.13 | ASP 16 | - | Cationic |
| LYS 76 | b1b2.13 | ASP 16 | - | VdWContact |
