Predicted complex interactions
CXCL7_HUMAN + ACKR3
SUMMARY
- Chemokine
- CXCL7_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- ACKR3 View partner entry
- Partner description
- UniProt: P25106; Gene: ackr3_human; Family: Chemokine
- Interactions detected
- 87
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| LEU 19 | NTc.Cm44 | MET 33 | - | Hydrophobic |
| LEU 19 | NTc.Cm44 | MET 33 | - | VdWContact |
| SER 21 | NTc.Cm42 | MET 33 | - | HBDonor |
| SER 21 | NTc.Cm42 | MET 33 | - | VdWContact |
| SER 21 | NTc.Cm42 | CYS 34 | - | VdWContact |
| ASP 22 | NTc.Cm41 | ASN 36 | - | HBAcceptor |
| ASP 22 | NTc.Cm41 | ASN 36 | - | HBDonor |
| ASP 22 | NTc.Cm41 | ASN 36 | - | VdWContact |
| LEU 23 | NTc.Cm40 | VAL 32 | - | VdWContact |
| LEU 23 | NTc.Cm40 | MET 33 | - | Hydrophobic |
| LEU 23 | NTc.Cm40 | MET 33 | - | VdWContact |
| LEU 23 | NTc.Cm40 | CYS 34 | - | Hydrophobic |
| LEU 23 | NTc.Cm40 | CYS 34 | - | VdWContact |
| TYR 24 | NTc.Cm39 | LYS 40 | - | Hydrophobic |
| TYR 24 | NTc.Cm39 | LYS 40 | - | PiCation |
| TYR 24 | NTc.Cm39 | LYS 40 | - | VdWContact |
| GLU 26 | NTc.Cm37 | GLU 290 | 7.28x27 | Hydrophobic |
| GLU 26 | NTc.Cm37 | GLU 290 | 7.28x27 | VdWContact |
| GLU 26 | NTc.Cm37 | HIS 291 | 7.29x28 | HBAcceptor |
| GLU 26 | NTc.Cm37 | HIS 291 | 7.29x28 | VdWContact |
| GLU 26 | NTc.Cm37 | PHE 294 | 7.32x31 | HBAcceptor |
| GLU 26 | NTc.Cm37 | PHE 294 | 7.32x31 | Hydrophobic |
| GLU 26 | NTc.Cm37 | PHE 294 | 7.32x31 | VdWContact |
| LEU 27 | NTc.Cm36 | ASP 275 | 6.58x58 | VdWContact |
| LEU 27 | NTc.Cm36 | ILE 279 | 6.62x62 | Hydrophobic |
| LEU 27 | NTc.Cm36 | GLU 290 | 7.28x27 | HBDonor |
| LEU 27 | NTc.Cm36 | GLU 290 | 7.28x27 | VdWContact |
| LEU 27 | NTc.Cm36 | LEU 293 | 7.31x30 | Hydrophobic |
| ARG 28 | NTc.Cm35 | ILE 205 | 5.31x32 | HBDonor |
| ARG 28 | NTc.Cm35 | ILE 205 | 5.31x32 | Hydrophobic |
| ARG 28 | NTc.Cm35 | ILE 205 | 5.31x32 | VdWContact |
| ARG 28 | NTc.Cm35 | LYS 206 | 5.32x33 | HBDonor |
| ARG 28 | NTc.Cm35 | LYS 206 | 5.32x33 | VdWContact |
| ARG 28 | NTc.Cm35 | LEU 209 | 5.35x36 | Hydrophobic |
| ARG 28 | NTc.Cm35 | LEU 209 | 5.35x36 | VdWContact |
| ARG 28 | NTc.Cm35 | ILE 210 | 5.36x37 | HBDonor |
| ARG 28 | NTc.Cm35 | ILE 210 | 5.36x37 | VdWContact |
| ARG 28 | NTc.Cm35 | GLU 213 | 5.39x40 | Cationic |
| ARG 28 | NTc.Cm35 | GLU 213 | 5.39x40 | HBDonor |
| ARG 28 | NTc.Cm35 | GLU 213 | 5.39x40 | VdWContact |
| ARG 28 | NTc.Cm35 | ILE 279 | 6.62x62 | VdWContact |
| MET 30 | NTc.Cm33 | HIS 281 | 6.64x64 | Hydrophobic |
| ILE 32 | NTc.Cm31 | GLU 202 | - | Hydrophobic |
| ILE 32 | NTc.Cm31 | GLU 202 | - | VdWContact |
| ILE 32 | NTc.Cm31 | ILE 205 | 5.31x32 | Hydrophobic |
| ILE 32 | NTc.Cm31 | ILE 205 | 5.31x32 | VdWContact |
| LYS 33 | NTc.Cm30 | GLU 202 | - | Cationic |
| LYS 33 | NTc.Cm30 | GLU 202 | - | Hydrophobic |
| LYS 33 | NTc.Cm30 | GLU 202 | - | VdWContact |
| HIS 39 | NTc.Cm24 | TRP 19 | - | Hydrophobic |
| HIS 39 | NTc.Cm24 | TRP 19 | - | VdWContact |
| LYS 41 | NTc.Cm22 | ILE 27 | - | VdWContact |
| ILE 43 | NTc.Cm20 | ILE 27 | - | VdWContact |
| GLN 44 | NTc.Cm19 | ILE 27 | - | Hydrophobic |
| GLN 44 | NTc.Cm19 | ILE 27 | - | VdWContact |
| GLN 44 | NTc.Cm19 | VAL 28 | - | VdWContact |
| SER 45 | NTc.Cm18 | VAL 29 | - | VdWContact |
| LEU 46 | NTc.Cm17 | VAL 29 | - | Hydrophobic |
| LEU 46 | NTc.Cm17 | VAL 29 | - | VdWContact |
| LEU 46 | NTc.Cm17 | THR 31 | - | VdWContact |
| VAL 48 | NTc.Cm15 | THR 31 | - | Hydrophobic |
| VAL 48 | NTc.Cm15 | THR 31 | - | VdWContact |
| LYS 51 | NTc.Cm12 | SER 188 | - | HBDonor |
| LYS 51 | NTc.Cm12 | SER 188 | - | VdWContact |
| LYS 51 | NTc.Cm12 | SER 190 | - | HBDonor |
| LYS 51 | NTc.Cm12 | SER 190 | - | VdWContact |
| GLY 52 | NTc.Cm11 | ARG 197 | 45.51x51 | HBAcceptor |
| GLY 52 | NTc.Cm11 | ARG 197 | 45.51x51 | VdWContact |
| THR 53 | NTc.Cm10 | ARG 197 | 45.51x51 | VdWContact |
| THR 53 | NTc.Cm10 | PHE 294 | 7.32x31 | Hydrophobic |
| HIS 54 | NTc.Cm9 | ARG 197 | 45.51x51 | VdWContact |
| CYS 55 | NTc.Cm8 | ARG 197 | 45.51x51 | HBAcceptor |
| CYS 55 | NTc.Cm8 | ARG 197 | 45.51x51 | VdWContact |
| ASN 56 | NTc.Cm7 | VAL 186 | - | VdWContact |
| ASN 56 | NTc.Cm7 | ARG 197 | 45.51x51 | VdWContact |
| ASN 56 | NTc.Cm7 | PHE 199 | - | VdWContact |
| LYS 65 | CX.5 | ASP 25 | - | Cationic |
| LYS 65 | CX.5 | ASP 25 | - | HBDonor |
| LYS 65 | CX.5 | ASP 25 | - | VdWContact |
| LYS 65 | CX.5 | ILE 27 | - | Hydrophobic |
| LYS 65 | CX.5 | ILE 27 | - | VdWContact |
| LYS 81 | B1.6 | PHE 14 | - | CationPi |
| LYS 81 | B1.6 | PHE 14 | - | VdWContact |
| LYS 86 | b1b2.8 | ILE 27 | - | VdWContact |
| LYS 86 | b1b2.8 | VAL 29 | - | HBDonor |
| LYS 86 | b1b2.8 | VAL 29 | - | Hydrophobic |
| LYS 86 | b1b2.8 | VAL 29 | - | VdWContact |
