Predicted complex interactions
CXCL9_HUMAN + ACKR3
SUMMARY
- Chemokine
- CXCL9_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- ACKR3 View partner entry
- Partner description
- UniProt: P25106; Gene: ackr3_human; Family: Chemokine
- Interactions detected
- 91
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| THR 1 | NTc.Cm30 | HIS 121 | 3.29x29 | Hydrophobic |
| THR 1 | NTc.Cm30 | HIS 121 | 3.29x29 | VdWContact |
| THR 1 | NTc.Cm30 | SER 125 | 3.33x33 | HBDonor |
| THR 1 | NTc.Cm30 | SER 125 | 3.33x33 | VdWContact |
| THR 1 | NTc.Cm30 | ASP 179 | 4.60x61 | Cationic |
| THR 1 | NTc.Cm30 | ASP 179 | 4.60x61 | HBDonor |
| THR 1 | NTc.Cm30 | ASP 179 | 4.60x61 | VdWContact |
| THR 1 | NTc.Cm30 | LEU 183 | 4.64x65 | Hydrophobic |
| PRO 2 | NTc.Cm29 | TRP 100 | 2.60x60 | Hydrophobic |
| PRO 2 | NTc.Cm29 | PHE 124 | 3.32x32 | Hydrophobic |
| PRO 2 | NTc.Cm29 | PHE 124 | 3.32x32 | VdWContact |
| PRO 2 | NTc.Cm29 | GLN 301 | 7.39x38 | Hydrophobic |
| PRO 2 | NTc.Cm29 | GLN 301 | 7.39x38 | VdWContact |
| VAL 3 | NTc.Cm28 | GLU 213 | 5.39x40 | Hydrophobic |
| VAL 3 | NTc.Cm28 | TYR 268 | 6.51x51 | HBDonor |
| VAL 3 | NTc.Cm28 | TYR 268 | 6.51x51 | Hydrophobic |
| VAL 3 | NTc.Cm28 | TYR 268 | 6.51x51 | VdWContact |
| VAL 3 | NTc.Cm28 | VAL 272 | 6.55x55 | Hydrophobic |
| VAL 3 | NTc.Cm28 | LEU 297 | 7.35x34 | VdWContact |
| VAL 4 | NTc.Cm27 | HIS 298 | 7.36x35 | Hydrophobic |
| VAL 4 | NTc.Cm27 | HIS 298 | 7.36x35 | VdWContact |
| ARG 5 | NTc.Cm26 | ASP 275 | 6.58x58 | Cationic |
| ARG 5 | NTc.Cm26 | ASP 275 | 6.58x58 | HBDonor |
| ARG 5 | NTc.Cm26 | ASP 275 | 6.58x58 | VdWContact |
| ARG 5 | NTc.Cm26 | SER 278 | 6.61x61 | HBDonor |
| ARG 5 | NTc.Cm26 | SER 278 | 6.61x61 | VdWContact |
| ARG 5 | NTc.Cm26 | ILE 279 | 6.62x62 | VdWContact |
| ARG 5 | NTc.Cm26 | LEU 297 | 7.35x34 | Hydrophobic |
| LYS 6 | NTc.Cm25 | ASN 108 | - | HBDonor |
| LYS 6 | NTc.Cm25 | ASN 108 | - | Hydrophobic |
| LYS 6 | NTc.Cm25 | ASN 108 | - | VdWContact |
| LYS 6 | NTc.Cm25 | TYR 195 | - | Hydrophobic |
| LYS 6 | NTc.Cm25 | ARG 197 | 45.51x51 | VdWContact |
| GLY 7 | NTc.Cm24 | ARG 197 | 45.51x51 | VdWContact |
| ARG 8 | NTc.Cm23 | LEU 209 | 5.35x36 | VdWContact |
| ARG 8 | NTc.Cm23 | GLU 213 | 5.39x40 | Cationic |
| ARG 8 | NTc.Cm23 | GLU 213 | 5.39x40 | HBDonor |
| ARG 8 | NTc.Cm23 | GLU 213 | 5.39x40 | VdWContact |
| ARG 8 | NTc.Cm23 | ASP 275 | 6.58x58 | Cationic |
| SER 10 | NTc.Cm21 | PHE 285 | - | VdWContact |
| ILE 12 | NTc.Cm19 | ILE 205 | 5.31x32 | Hydrophobic |
| ILE 12 | NTc.Cm19 | LYS 206 | 5.32x33 | Hydrophobic |
| ILE 12 | NTc.Cm19 | LEU 209 | 5.35x36 | Hydrophobic |
| ILE 12 | NTc.Cm19 | LEU 209 | 5.35x36 | VdWContact |
| ILE 12 | NTc.Cm19 | ILE 279 | 6.62x62 | Hydrophobic |
| ILE 12 | NTc.Cm19 | ILE 279 | 6.62x62 | VdWContact |
| LEU 27 | NTc.Cm4 | VAL 29 | - | Hydrophobic |
| LEU 27 | NTc.Cm4 | VAL 29 | - | VdWContact |
| LYS 28 | NTc.Cm3 | VAL 32 | - | Hydrophobic |
| GLN 29 | NTc.Cm2 | VAL 29 | - | Hydrophobic |
| GLN 29 | NTc.Cm2 | ASP 30 | - | HBDonor |
| GLN 29 | NTc.Cm2 | ASP 30 | - | VdWContact |
| GLN 29 | NTc.Cm2 | THR 31 | - | Hydrophobic |
| GLN 29 | NTc.Cm2 | THR 31 | - | VdWContact |
| GLN 29 | NTc.Cm2 | VAL 32 | - | HBAcceptor |
| GLN 29 | NTc.Cm2 | VAL 32 | - | VdWContact |
| PHE 30 | NTc.Cm1 | VAL 32 | - | Hydrophobic |
| PHE 30 | NTc.Cm1 | VAL 32 | - | VdWContact |
| PHE 30 | NTc.Cm1 | PHE 285 | - | Hydrophobic |
| PHE 30 | NTc.Cm1 | PHE 285 | - | PiStacking |
| PHE 30 | NTc.Cm1 | PHE 285 | - | VdWContact |
| ALA 31 | CX.1 | VAL 32 | - | VdWContact |
| ALA 31 | CX.1 | MET 33 | - | Hydrophobic |
| ALA 31 | CX.1 | MET 33 | - | VdWContact |
| SER 35 | cxb1.2 | GLU 290 | 7.28x27 | HBDonor |
| SER 35 | cxb1.2 | GLU 290 | 7.28x27 | VdWContact |
| GLU 37 | cxb1.6 | SER 188 | - | HBAcceptor |
| GLU 37 | cxb1.6 | SER 188 | - | VdWContact |
| ILE 42 | cxb1.14 | PHE 285 | - | Hydrophobic |
| GLN 50 | B1.6 | HIS 281 | 6.64x64 | Hydrophobic |
| GLN 50 | B1.6 | HIS 281 | 6.64x64 | VdWContact |
| GLN 50 | B1.6 | PRO 284 | - | VdWContact |
| GLN 50 | B1.6 | PHE 285 | - | HBAcceptor |
| GLN 50 | B1.6 | PHE 285 | - | VdWContact |
| ILE 64 | B2.3 | VAL 29 | - | Hydrophobic |
| LYS 65 | B2.4 | TRP 19 | - | Hydrophobic |
| LYS 65 | B2.4 | TRP 19 | - | VdWContact |
| TRP 67 | B2.6 | VAL 29 | - | Hydrophobic |
| GLU 68 | b2b3.2 | ILE 27 | - | Hydrophobic |
| GLU 68 | b2b3.2 | ILE 27 | - | VdWContact |
| GLU 68 | b2b3.2 | VAL 29 | - | HBAcceptor |
| GLU 68 | b2b3.2 | VAL 29 | - | Hydrophobic |
| GLU 68 | b2b3.2 | VAL 29 | - | VdWContact |
| VAL 71 | b2b3.12 | ILE 27 | - | Hydrophobic |
| VAL 71 | b2b3.12 | ILE 27 | - | VdWContact |
| SER 72 | B3.1 | ASP 25 | - | HBDonor |
| SER 72 | B3.1 | ASP 25 | - | VdWContact |
| SER 72 | B3.1 | ILE 27 | - | VdWContact |
| LYS 76 | b3h.1 | ASP 25 | - | Cationic |
| LYS 76 | b3h.1 | ASP 25 | - | HBDonor |
| LYS 76 | b3h.1 | ASP 25 | - | VdWContact |
