Predicted complex interactions
XCL1_HUMAN + ACKR3
SUMMARY
- Chemokine
- XCL1_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- ACKR3 View partner entry
- Partner description
- UniProt: P25106; Gene: ackr3_human; Family: Chemokine
- Interactions detected
- 150
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| VAL 1 | NTc.Cm30 | HIS 121 | 3.29x29 | Hydrophobic |
| VAL 1 | NTc.Cm30 | PHE 124 | 3.32x32 | Hydrophobic |
| VAL 1 | NTc.Cm30 | LEU 128 | 3.36x36 | Hydrophobic |
| VAL 1 | NTc.Cm30 | ASP 179 | 4.60x61 | Cationic |
| VAL 1 | NTc.Cm30 | ASP 179 | 4.60x61 | HBDonor |
| VAL 1 | NTc.Cm30 | ASP 179 | 4.60x61 | VdWContact |
| GLY 2 | NTc.Cm29 | TYR 268 | 6.51x51 | VdWContact |
| GLU 4 | NTc.Cm27 | TYR 195 | - | VdWContact |
| GLU 4 | NTc.Cm27 | CYS 196 | 45.50x50 | HBAcceptor |
| GLU 4 | NTc.Cm27 | CYS 196 | 45.50x50 | VdWContact |
| GLU 4 | NTc.Cm27 | ARG 197 | 45.51x51 | Anionic |
| GLU 4 | NTc.Cm27 | ARG 197 | 45.51x51 | HBAcceptor |
| GLU 4 | NTc.Cm27 | ARG 197 | 45.51x51 | VdWContact |
| VAL 5 | NTc.Cm26 | PHE 294 | 7.32x31 | Hydrophobic |
| VAL 5 | NTc.Cm26 | LEU 297 | 7.35x34 | Hydrophobic |
| VAL 5 | NTc.Cm26 | HIS 298 | 7.36x35 | Hydrophobic |
| SER 6 | NTc.Cm25 | ARG 197 | 45.51x51 | VdWContact |
| ASP 7 | NTc.Cm24 | PRO 11 | - | Hydrophobic |
| ASP 7 | NTc.Cm24 | PRO 11 | - | VdWContact |
| ASP 7 | NTc.Cm24 | GLY 12 | - | VdWContact |
| ASP 7 | NTc.Cm24 | ARG 197 | 45.51x51 | Anionic |
| ASP 7 | NTc.Cm24 | ARG 197 | 45.51x51 | HBAcceptor |
| ASP 7 | NTc.Cm24 | ARG 197 | 45.51x51 | VdWContact |
| LYS 8 | NTc.Cm23 | LEU 209 | 5.35x36 | Hydrophobic |
| LYS 8 | NTc.Cm23 | LEU 209 | 5.35x36 | VdWContact |
| ARG 9 | NTc.Cm22 | LEU 274 | 6.57x57 | HBDonor |
| ARG 9 | NTc.Cm22 | LEU 274 | 6.57x57 | VdWContact |
| ARG 9 | NTc.Cm22 | ASP 275 | 6.58x58 | Cationic |
| ARG 9 | NTc.Cm22 | ASP 275 | 6.58x58 | HBDonor |
| ARG 9 | NTc.Cm22 | ASP 275 | 6.58x58 | VdWContact |
| ARG 9 | NTc.Cm22 | SER 278 | 6.61x61 | VdWContact |
| ARG 9 | NTc.Cm22 | PHE 285 | - | VdWContact |
| ARG 9 | NTc.Cm22 | LEU 289 | 7.27x26 | VdWContact |
| ARG 9 | NTc.Cm22 | GLU 290 | 7.28x27 | VdWContact |
| ARG 9 | NTc.Cm22 | LEU 293 | 7.31x30 | VdWContact |
| THR 10 | NTc.Cm21 | PHE 285 | - | Hydrophobic |
| THR 10 | NTc.Cm21 | PHE 285 | - | VdWContact |
| THR 10 | NTc.Cm21 | GLU 290 | 7.28x27 | HBDonor |
| THR 10 | NTc.Cm21 | GLU 290 | 7.28x27 | Hydrophobic |
| THR 10 | NTc.Cm21 | GLU 290 | 7.28x27 | VdWContact |
| CYS 11 | NTc.Cm20 | GLY 12 | - | VdWContact |
| CYS 11 | NTc.Cm20 | VAL 32 | - | Hydrophobic |
| CYS 11 | NTc.Cm20 | VAL 32 | - | VdWContact |
| CYS 11 | NTc.Cm20 | PHE 285 | - | VdWContact |
| VAL 12 | NTc.Cm19 | VAL 32 | - | HBDonor |
| VAL 12 | NTc.Cm19 | VAL 32 | - | VdWContact |
| VAL 12 | NTc.Cm19 | MET 33 | - | HBDonor |
| VAL 12 | NTc.Cm19 | CYS 34 | - | Hydrophobic |
| VAL 12 | NTc.Cm19 | CYS 34 | - | VdWContact |
| VAL 12 | NTc.Cm19 | CYS 287 | 7.25x24 | Hydrophobic |
| VAL 12 | NTc.Cm19 | CYS 287 | 7.25x24 | VdWContact |
| SER 13 | NTc.Cm18 | VAL 32 | - | VdWContact |
| SER 13 | NTc.Cm18 | MET 33 | - | HBAcceptor |
| SER 13 | NTc.Cm18 | MET 33 | - | HBDonor |
| SER 13 | NTc.Cm18 | MET 33 | - | VdWContact |
| LEU 14 | NTc.Cm17 | ASP 30 | - | Hydrophobic |
| LEU 14 | NTc.Cm17 | ASP 30 | - | VdWContact |
| LEU 14 | NTc.Cm17 | VAL 32 | - | Hydrophobic |
| LEU 14 | NTc.Cm17 | VAL 32 | - | VdWContact |
| THR 15 | NTc.Cm16 | ASN 13 | - | HBDonor |
| THR 15 | NTc.Cm16 | ASN 13 | - | VdWContact |
| THR 15 | NTc.Cm16 | SER 15 | - | VdWContact |
| THR 15 | NTc.Cm16 | ASP 30 | - | VdWContact |
| THR 15 | NTc.Cm16 | THR 31 | - | HBAcceptor |
| THR 15 | NTc.Cm16 | THR 31 | - | HBDonor |
| THR 15 | NTc.Cm16 | THR 31 | - | VdWContact |
| THR 15 | NTc.Cm16 | MET 33 | - | VdWContact |
| THR 16 | NTc.Cm15 | ASP 30 | - | HBDonor |
| THR 16 | NTc.Cm15 | ASP 30 | - | VdWContact |
| GLN 17 | NTc.Cm14 | PHE 14 | - | VdWContact |
| GLN 17 | NTc.Cm14 | SER 15 | - | HBDonor |
| GLN 17 | NTc.Cm14 | SER 15 | - | VdWContact |
| GLN 17 | NTc.Cm14 | ILE 17 | - | HBDonor |
| GLN 17 | NTc.Cm14 | ILE 17 | - | VdWContact |
| GLN 17 | NTc.Cm14 | VAL 29 | - | HBAcceptor |
| GLN 17 | NTc.Cm14 | VAL 29 | - | VdWContact |
| GLN 17 | NTc.Cm14 | THR 31 | - | Hydrophobic |
| ARG 18 | NTc.Cm13 | CYS 21 | - | Cationic |
| ARG 18 | NTc.Cm13 | CYS 21 | - | VdWContact |
| ARG 18 | NTc.Cm13 | ILE 27 | - | VdWContact |
| LEU 19 | NTc.Cm12 | PHE 14 | - | Hydrophobic |
| LEU 19 | NTc.Cm12 | TRP 19 | - | Hydrophobic |
| LEU 19 | NTc.Cm12 | TRP 19 | - | VdWContact |
| LEU 19 | NTc.Cm12 | CYS 26 | - | VdWContact |
| LEU 19 | NTc.Cm12 | ILE 27 | - | HBAcceptor |
| LEU 19 | NTc.Cm12 | ILE 27 | - | Hydrophobic |
| LEU 19 | NTc.Cm12 | ILE 27 | - | VdWContact |
| LEU 19 | NTc.Cm12 | VAL 29 | - | Hydrophobic |
| LEU 19 | NTc.Cm12 | VAL 29 | - | VdWContact |
| LEU 19 | NTc.Cm12 | THR 31 | - | Hydrophobic |
| PRO 20 | NTc.Cm11 | TRP 19 | - | Hydrophobic |
| PRO 20 | NTc.Cm11 | TRP 19 | - | VdWContact |
| PRO 20 | NTc.Cm11 | ASP 25 | - | VdWContact |
| PRO 20 | NTc.Cm11 | CYS 26 | - | Hydrophobic |
| PRO 20 | NTc.Cm11 | CYS 26 | - | VdWContact |
| VAL 21 | NTc.Cm10 | ASP 25 | - | HBDonor |
| VAL 21 | NTc.Cm10 | ASP 25 | - | VdWContact |
| VAL 21 | NTc.Cm10 | ILE 27 | - | Hydrophobic |
| VAL 21 | NTc.Cm10 | ILE 27 | - | VdWContact |
| ARG 23 | NTc.Cm8 | TRP 19 | - | CationPi |
| ARG 23 | NTc.Cm8 | TRP 19 | - | Hydrophobic |
| ARG 23 | NTc.Cm8 | TRP 19 | - | VdWContact |
| ILE 24 | NTc.Cm7 | ILE 27 | - | Hydrophobic |
| LYS 25 | NTc.Cm6 | HIS 203 | - | HBDonor |
| LYS 25 | NTc.Cm6 | HIS 203 | - | VdWContact |
| LYS 25 | NTc.Cm6 | GLU 207 | 5.33x34 | Cationic |
| LYS 25 | NTc.Cm6 | GLU 207 | 5.33x34 | HBDonor |
| LYS 25 | NTc.Cm6 | GLU 207 | 5.33x34 | VdWContact |
| THR 30 | NTc.Cm1 | HIS 281 | 6.64x64 | Hydrophobic |
| ILE 38 | cxb1.8 | HIS 281 | 6.64x64 | Hydrophobic |
| ILE 38 | cxb1.8 | HIS 281 | 6.64x64 | VdWContact |
| ILE 38 | cxb1.8 | PHE 285 | - | Hydrophobic |
| ILE 40 | cxb1.11 | LYS 206 | 5.32x33 | VdWContact |
| THR 41 | cxb1.14 | PHE 14 | - | Hydrophobic |
| THR 41 | cxb1.14 | TRP 19 | - | Hydrophobic |
| LYS 42 | cxb1.15 | GLU 202 | - | VdWContact |
| ARG 43 | cxb1.16 | PHE 6 | - | CationPi |
| ARG 43 | cxb1.16 | PHE 6 | - | VdWContact |
| ARG 43 | cxb1.16 | GLU 202 | - | Cationic |
| ARG 43 | cxb1.16 | GLU 202 | - | HBDonor |
| ARG 43 | cxb1.16 | GLU 202 | - | Hydrophobic |
| ARG 43 | cxb1.16 | GLU 202 | - | VdWContact |
| ARG 43 | cxb1.16 | ILE 205 | 5.31x32 | VdWContact |
| LEU 45 | B1.2 | PHE 14 | - | Hydrophobic |
| LYS 46 | B1.3 | PHE 14 | - | VdWContact |
| LYS 46 | B1.3 | LYS 206 | 5.32x33 | VdWContact |
| LYS 46 | B1.3 | SER 278 | 6.61x61 | VdWContact |
| LYS 46 | B1.3 | ILE 279 | 6.62x62 | HBDonor |
| LYS 46 | B1.3 | ILE 279 | 6.62x62 | VdWContact |
| LYS 46 | B1.3 | HIS 281 | 6.64x64 | Hydrophobic |
| LYS 46 | B1.3 | HIS 281 | 6.64x64 | VdWContact |
| VAL 47 | B1.4 | PHE 14 | - | Hydrophobic |
| VAL 47 | B1.4 | PHE 14 | - | VdWContact |
| VAL 47 | B1.4 | VAL 29 | - | Hydrophobic |
| VAL 47 | B1.4 | VAL 29 | - | VdWContact |
| VAL 47 | B1.4 | THR 31 | - | Hydrophobic |
| VAL 47 | B1.4 | THR 31 | - | VdWContact |
| CYS 48 | B1.5 | ASP 30 | - | VdWContact |
| CYS 48 | B1.5 | VAL 32 | - | Hydrophobic |
| CYS 48 | B1.5 | VAL 32 | - | VdWContact |
| CYS 48 | B1.5 | PHE 285 | - | Hydrophobic |
| CYS 48 | B1.5 | PHE 285 | - | VdWContact |
| TRP 55 | b1b2.14 | VAL 28 | - | VdWContact |
| TRP 55 | b1b2.14 | VAL 29 | - | VdWContact |
| TRP 55 | b1b2.14 | ASP 30 | - | HBAcceptor |
| TRP 55 | b1b2.14 | ASP 30 | - | VdWContact |
| VAL 56 | b1b2.16 | VAL 28 | - | HBDonor |
| VAL 56 | b1b2.16 | VAL 28 | - | VdWContact |
| VAL 59 | B2.3 | ILE 27 | - | Hydrophobic |
| VAL 59 | B2.3 | ILE 27 | - | VdWContact |
