Predicted complex interactions
CCL22_HUMAN + ACKR1
SUMMARY
- Chemokine
- CCL22_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- ACKR1 View partner entry
- Partner description
- UniProt: Q16570; Gene: ackr1_human; Family: Chemokine
- Interactions detected
- 95
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLY 1 | NTc.Cm35 | LEU 116 | 2.60x60 | VdWContact |
| GLY 1 | NTc.Cm35 | GLU 290 | 7.39x38 | Cationic |
| GLY 1 | NTc.Cm35 | GLU 290 | 7.39x38 | VdWContact |
| PRO 2 | NTc.Cm34 | LEU 116 | 2.60x60 | Hydrophobic |
| PRO 2 | NTc.Cm34 | LEU 116 | 2.60x60 | VdWContact |
| PRO 2 | NTc.Cm34 | TYR 133 | 3.29x29 | HBAcceptor |
| PRO 2 | NTc.Cm34 | TYR 133 | 3.29x29 | Hydrophobic |
| PRO 2 | NTc.Cm34 | TYR 133 | 3.29x29 | VdWContact |
| PRO 2 | NTc.Cm34 | TRP 136 | 3.32x32 | Hydrophobic |
| PRO 2 | NTc.Cm34 | TRP 136 | 3.32x32 | VdWContact |
| PRO 2 | NTc.Cm34 | TYR 137 | 3.33x33 | Hydrophobic |
| PRO 2 | NTc.Cm34 | TYR 137 | 3.33x33 | VdWContact |
| PRO 2 | NTc.Cm34 | LEU 197 | 45.52x52 | VdWContact |
| PRO 2 | NTc.Cm34 | GLU 290 | 7.39x38 | Hydrophobic |
| PRO 2 | NTc.Cm34 | GLU 290 | 7.39x38 | VdWContact |
| TYR 3 | NTc.Cm33 | TYR 137 | 3.33x33 | Hydrophobic |
| TYR 3 | NTc.Cm33 | TYR 137 | 3.33x33 | VdWContact |
| TYR 3 | NTc.Cm33 | LEU 197 | 45.52x52 | Hydrophobic |
| TYR 3 | NTc.Cm33 | HIS 210 | 5.42x42 | HBDonor |
| TYR 3 | NTc.Cm33 | HIS 210 | 5.42x42 | Hydrophobic |
| TYR 3 | NTc.Cm33 | HIS 210 | 5.42x42 | VdWContact |
| TYR 3 | NTc.Cm33 | HIS 256 | 6.51x51 | Hydrophobic |
| TYR 3 | NTc.Cm33 | HIS 256 | 6.51x51 | VdWContact |
| TYR 3 | NTc.Cm33 | LEU 260 | 6.55x55 | Hydrophobic |
| TYR 3 | NTc.Cm33 | LEU 260 | 6.55x55 | VdWContact |
| TYR 3 | NTc.Cm33 | GLU 290 | 7.39x38 | VdWContact |
| GLY 4 | NTc.Cm32 | GLU 290 | 7.39x38 | VdWContact |
| ALA 5 | NTc.Cm31 | LEU 286 | 7.35x34 | Hydrophobic |
| ALA 5 | NTc.Cm31 | LEU 286 | 7.35x34 | VdWContact |
| ASN 6 | NTc.Cm30 | THR 196 | 45.51x51 | VdWContact |
| ASN 6 | NTc.Cm30 | ARG 267 | 6.62x62 | HBAcceptor |
| ASN 6 | NTc.Cm30 | ARG 267 | 6.62x62 | VdWContact |
| MET 7 | NTc.Cm29 | ARG 267 | 6.62x62 | HBAcceptor |
| MET 7 | NTc.Cm29 | ARG 267 | 6.62x62 | VdWContact |
| MET 7 | NTc.Cm29 | GLN 279 | 7.28x27 | Hydrophobic |
| MET 7 | NTc.Cm29 | LEU 282 | 7.31x30 | Hydrophobic |
| MET 7 | NTc.Cm29 | ASP 283 | 7.32x31 | Hydrophobic |
| MET 7 | NTc.Cm29 | ASP 283 | 7.32x31 | VdWContact |
| MET 7 | NTc.Cm29 | LEU 286 | 7.35x34 | Hydrophobic |
| ASP 9 | NTc.Cm27 | SER 53 | - | VdWContact |
| SER 10 | NTc.Cm26 | SER 53 | - | VdWContact |
| SER 10 | NTc.Cm26 | GLN 279 | 7.28x27 | HBAcceptor |
| SER 10 | NTc.Cm26 | GLN 279 | 7.28x27 | VdWContact |
| VAL 11 | NTc.Cm25 | PRO 50 | - | Hydrophobic |
| VAL 11 | NTc.Cm25 | PRO 50 | - | VdWContact |
| VAL 11 | NTc.Cm25 | CYS 51 | - | VdWContact |
| VAL 11 | NTc.Cm25 | HIS 52 | - | Hydrophobic |
| CYS 12 | NTc.Cm24 | CYS 51 | - | HBAcceptor |
| CYS 12 | NTc.Cm24 | CYS 51 | - | HBDonor |
| CYS 12 | NTc.Cm24 | CYS 51 | - | VdWContact |
| ARG 14 | NTc.Cm22 | CYS 51 | - | Hydrophobic |
| ARG 14 | NTc.Cm22 | CYS 51 | - | VdWContact |
| ARG 14 | NTc.Cm22 | LEU 273 | - | HBDonor |
| ARG 14 | NTc.Cm22 | LEU 273 | - | VdWContact |
| ARG 14 | NTc.Cm22 | SER 274 | - | VdWContact |
| VAL 17 | NTc.Cm19 | ALA 48 | - | Hydrophobic |
| ARG 18 | NTc.Cm18 | ASN 44 | - | VdWContact |
| TYR 19 | NTc.Cm17 | TRP 26 | - | Hydrophobic |
| TYR 19 | NTc.Cm17 | TYR 41 | - | Hydrophobic |
| TYR 19 | NTc.Cm17 | TYR 41 | - | PiStacking |
| TYR 19 | NTc.Cm17 | TYR 41 | - | VdWContact |
| TYR 19 | NTc.Cm17 | ASN 44 | - | Hydrophobic |
| TYR 19 | NTc.Cm17 | LEU 45 | - | Hydrophobic |
| TYR 19 | NTc.Cm17 | LEU 45 | - | VdWContact |
| PRO 22 | NTc.Cm14 | TRP 26 | - | Hydrophobic |
| PRO 22 | NTc.Cm14 | TRP 26 | - | VdWContact |
| PRO 22 | NTc.Cm14 | TYR 30 | - | Hydrophobic |
| PRO 22 | NTc.Cm14 | TYR 30 | - | VdWContact |
| ARG 24 | NTc.Cm12 | VAL 25 | - | HBDonor |
| ARG 24 | NTc.Cm12 | VAL 25 | - | VdWContact |
| ARG 24 | NTc.Cm12 | TRP 26 | - | VdWContact |
| ARG 24 | NTc.Cm12 | SER 29 | - | VdWContact |
| VAL 25 | NTc.Cm11 | TRP 26 | - | Hydrophobic |
| CYS 36 | CX.1 | LYS 269 | 6.64x64 | HBAcceptor |
| CYS 36 | CX.1 | LYS 269 | 6.64x64 | VdWContact |
| PRO 37 | CX.5 | LYS 269 | 6.64x64 | HBAcceptor |
| PRO 37 | CX.5 | LYS 269 | 6.64x64 | VdWContact |
| PRO 37 | CX.5 | LEU 272 | - | Hydrophobic |
| VAL 42 | cxb1.7 | PRO 50 | - | Hydrophobic |
| ARG 47 | cxb1.15 | LEU 20 | - | HBDonor |
| ARG 47 | cxb1.15 | LEU 20 | - | VdWContact |
| ARG 47 | cxb1.15 | ASP 21 | - | HBDonor |
| ARG 47 | cxb1.15 | ASP 21 | - | VdWContact |
| ARG 47 | cxb1.15 | PHE 22 | - | CationPi |
| ARG 47 | cxb1.15 | PHE 22 | - | Hydrophobic |
| ARG 47 | cxb1.15 | PHE 22 | - | VdWContact |
| LYS 49 | B1.1 | PHE 22 | - | Hydrophobic |
| GLU 50 | B1.2 | PRO 50 | - | Hydrophobic |
| GLU 50 | B1.2 | HIS 52 | - | HBAcceptor |
| GLU 50 | B1.2 | HIS 52 | - | VdWContact |
| ILE 51 | B1.3 | LEU 45 | - | Hydrophobic |
| ILE 51 | B1.3 | LEU 45 | - | VdWContact |
| ILE 51 | B1.3 | ALA 48 | - | Hydrophobic |
| CYS 52 | B1.4 | ALA 48 | - | HBDonor |
| CYS 52 | B1.4 | ALA 48 | - | VdWContact |
