Predicted complex interactions
CCL15_HUMAN + ACKR4
SUMMARY
- Chemokine
- CCL15_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- ACKR4 View partner entry
- Partner description
- UniProt: Q9NPB9; Gene: ackr4_human; Family: Chemokine
- Interactions detected
- 117
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| VAL 21 | NTc.Cm32 | ASN 181 | - | HBAcceptor |
| VAL 21 | NTc.Cm32 | ASN 181 | - | VdWContact |
| VAL 22 | NTc.Cm31 | ASN 181 | - | VdWContact |
| VAL 22 | NTc.Cm31 | ARG 183 | - | HBAcceptor |
| VAL 22 | NTc.Cm31 | ARG 183 | - | VdWContact |
| LEU 23 | NTc.Cm30 | ASN 179 | - | VdWContact |
| LEU 23 | NTc.Cm30 | ARG 183 | - | VdWContact |
| LEU 23 | NTc.Cm30 | ILE 185 | 45.51x51 | Hydrophobic |
| LEU 23 | NTc.Cm30 | ILE 185 | 45.51x51 | VdWContact |
| ASN 24 | NTc.Cm29 | ASN 100 | 2.63x63 | HBAcceptor |
| ASN 24 | NTc.Cm29 | ASN 100 | 2.63x63 | VdWContact |
| ASN 24 | NTc.Cm29 | ALA 101 | 2.64x64 | HBDonor |
| ASN 24 | NTc.Cm29 | ALA 101 | 2.64x64 | VdWContact |
| ASN 24 | NTc.Cm29 | ARG 183 | - | HBAcceptor |
| ASN 24 | NTc.Cm29 | ARG 183 | - | VdWContact |
| SER 25 | NTc.Cm28 | TRP 97 | 2.60x60 | VdWContact |
| SER 25 | NTc.Cm28 | ASN 100 | 2.63x63 | HBAcceptor |
| SER 25 | NTc.Cm28 | ASN 100 | 2.63x63 | HBDonor |
| SER 25 | NTc.Cm28 | ASN 100 | 2.63x63 | VdWContact |
| SER 25 | NTc.Cm28 | CYS 184 | 45.50x50 | HBAcceptor |
| SER 25 | NTc.Cm28 | CYS 184 | 45.50x50 | VdWContact |
| PHE 26 | NTc.Cm27 | LEU 44 | 1.35x35 | Hydrophobic |
| PHE 26 | NTc.Cm27 | LEU 48 | 1.39x39 | Hydrophobic |
| PHE 26 | NTc.Cm27 | TRP 97 | 2.60x60 | Hydrophobic |
| PHE 26 | NTc.Cm27 | TRP 97 | 2.60x60 | VdWContact |
| PHE 26 | NTc.Cm27 | TYR 119 | 3.32x32 | Hydrophobic |
| PHE 26 | NTc.Cm27 | GLU 289 | 7.39x38 | Hydrophobic |
| PHE 26 | NTc.Cm27 | GLU 289 | 7.39x38 | VdWContact |
| PHE 26 | NTc.Cm27 | LEU 293 | 7.43x42 | Hydrophobic |
| PHE 26 | NTc.Cm27 | LEU 293 | 7.43x42 | VdWContact |
| HIS 27 | NTc.Cm26 | ARG 263 | 6.58x58 | VdWContact |
| HIS 27 | NTc.Cm26 | ILE 285 | 7.35x34 | Hydrophobic |
| HIS 27 | NTc.Cm26 | ILE 285 | 7.35x34 | VdWContact |
| HIS 27 | NTc.Cm26 | GLN 286 | 7.36x35 | HBAcceptor |
| HIS 27 | NTc.Cm26 | GLN 286 | 7.36x35 | VdWContact |
| PHE 28 | NTc.Cm25 | ARG 37 | 1.28x28 | Hydrophobic |
| PHE 28 | NTc.Cm25 | ARG 37 | 1.28x28 | VdWContact |
| ALA 29 | NTc.Cm24 | LYS 33 | - | Hydrophobic |
| ALA 29 | NTc.Cm24 | LYS 33 | - | VdWContact |
| ALA 29 | NTc.Cm24 | VAL 36 | 1.27x27 | Hydrophobic |
| ALA 29 | NTc.Cm24 | VAL 36 | 1.27x27 | VdWContact |
| ALA 29 | NTc.Cm24 | ARG 37 | 1.28x28 | HBAcceptor |
| ALA 29 | NTc.Cm24 | ARG 37 | 1.28x28 | Hydrophobic |
| ALA 29 | NTc.Cm24 | ARG 37 | 1.28x28 | VdWContact |
| ALA 29 | NTc.Cm24 | ASP 282 | 7.32x31 | Hydrophobic |
| ALA 30 | NTc.Cm23 | LYS 33 | - | HBAcceptor |
| ALA 30 | NTc.Cm23 | LYS 33 | - | VdWContact |
| ASP 31 | NTc.Cm22 | ILE 30 | - | Hydrophobic |
| ASP 31 | NTc.Cm22 | ILE 30 | - | VdWContact |
| ASP 31 | NTc.Cm22 | CYS 31 | - | VdWContact |
| ASP 31 | NTc.Cm22 | ILE 32 | - | VdWContact |
| ASP 31 | NTc.Cm22 | LYS 33 | - | HBAcceptor |
| ASP 31 | NTc.Cm22 | LYS 33 | - | VdWContact |
| ASP 31 | NTc.Cm22 | ARG 37 | 1.28x28 | Anionic |
| ASP 31 | NTc.Cm22 | ARG 37 | 1.28x28 | HBAcceptor |
| ASP 31 | NTc.Cm22 | ARG 37 | 1.28x28 | VdWContact |
| CYS 32 | NTc.Cm21 | CYS 31 | - | HBAcceptor |
| CYS 32 | NTc.Cm21 | CYS 31 | - | HBDonor |
| CYS 32 | NTc.Cm21 | CYS 31 | - | VdWContact |
| CYS 32 | NTc.Cm21 | LYS 33 | - | Anionic |
| CYS 32 | NTc.Cm21 | LYS 33 | - | VdWContact |
| THR 34 | NTc.Cm19 | CYS 31 | - | Hydrophobic |
| THR 34 | NTc.Cm19 | ILE 272 | - | Hydrophobic |
| THR 34 | NTc.Cm19 | THR 273 | - | VdWContact |
| THR 34 | NTc.Cm19 | CYS 275 | 7.25x24 | VdWContact |
| SER 35 | NTc.Cm18 | GLU 28 | - | HBDonor |
| SER 35 | NTc.Cm18 | GLU 28 | - | VdWContact |
| TYR 36 | NTc.Cm17 | GLU 28 | - | VdWContact |
| ILE 37 | NTc.Cm16 | TYR 27 | - | Hydrophobic |
| ILE 37 | NTc.Cm16 | TYR 27 | - | VdWContact |
| ILE 37 | NTc.Cm16 | GLU 28 | - | VdWContact |
| GLN 39 | NTc.Cm14 | GLN 26 | - | HBDonor |
| GLN 39 | NTc.Cm14 | GLN 26 | - | VdWContact |
| ILE 41 | NTc.Cm12 | TYR 27 | - | Hydrophobic |
| PRO 42 | NTc.Cm11 | TYR 22 | - | Hydrophobic |
| PRO 42 | NTc.Cm11 | TYR 27 | - | Hydrophobic |
| PRO 42 | NTc.Cm11 | TYR 27 | - | VdWContact |
| LEU 45 | NTc.Cm8 | TYR 22 | - | Hydrophobic |
| LEU 45 | NTc.Cm8 | TYR 22 | - | VdWContact |
| MET 46 | NTc.Cm7 | TYR 27 | - | Hydrophobic |
| PHE 50 | NTc.Cm3 | ILE 30 | - | Hydrophobic |
| GLU 51 | NTc.Cm2 | ARG 190 | - | Anionic |
| GLU 51 | NTc.Cm2 | ARG 190 | - | HBAcceptor |
| GLU 51 | NTc.Cm2 | ARG 190 | - | VdWContact |
| SER 54 | CX.5 | PRO 186 | 45.52x52 | VdWContact |
| SER 54 | CX.5 | PHE 188 | - | HBAcceptor |
| SER 54 | CX.5 | PHE 188 | - | VdWContact |
| SER 54 | CX.5 | LYS 197 | 5.35x36 | HBAcceptor |
| SER 54 | CX.5 | LYS 197 | 5.35x36 | VdWContact |
| GLU 55 | cxb1.1 | PRO 186 | 45.52x52 | Hydrophobic |
| GLU 55 | cxb1.1 | ARG 263 | 6.58x58 | VdWContact |
| CYS 56 | cxb1.2 | LYS 197 | 5.35x36 | VdWContact |
| SER 57 | cxb1.5 | ASP 266 | 6.61x61 | HBDonor |
| SER 57 | cxb1.5 | ASP 266 | 6.61x61 | VdWContact |
| LYS 58 | cxb1.6 | SER 270 | - | HBDonor |
| LYS 58 | cxb1.6 | SER 270 | - | VdWContact |
| LYS 58 | cxb1.6 | ILE 272 | - | VdWContact |
| PRO 59 | cxb1.7 | THR 194 | - | Hydrophobic |
| ILE 62 | cxb1.11 | ILE 30 | - | Hydrophobic |
| ILE 62 | cxb1.11 | ILE 30 | - | VdWContact |
| THR 65 | cxb1.16 | TYR 24 | - | Hydrophobic |
| THR 65 | cxb1.16 | TYR 24 | - | VdWContact |
| LYS 67 | B1.2 | TYR 24 | - | Hydrophobic |
| ARG 69 | B1.4 | TYR 24 | - | VdWContact |
| GLN 70 | B1.5 | ILE 30 | - | HBAcceptor |
| GLN 70 | B1.5 | ILE 30 | - | Hydrophobic |
| GLN 70 | B1.5 | ILE 30 | - | VdWContact |
| VAL 71 | B1.6 | TYR 27 | - | Hydrophobic |
| CYS 72 | B1.7 | GLU 28 | - | HBDonor |
| CYS 72 | B1.7 | GLU 28 | - | Hydrophobic |
| CYS 72 | B1.7 | GLU 28 | - | VdWContact |
| CYS 72 | B1.7 | ILE 30 | - | VdWContact |
| MET 84 | B2.4 | ARG 190 | - | VdWContact |
| SER 91 | B3.1 | ASP 180 | - | HBDonor |
| SER 91 | B3.1 | ASP 180 | - | VdWContact |
| ILE 92 | B3.2 | ASN 181 | - | HBAcceptor |
| ILE 92 | B3.2 | ASN 181 | - | VdWContact |
