Predicted complex interactions
CCL17_HUMAN + ACKR4
SUMMARY
- Chemokine
- CCL17_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- ACKR4 View partner entry
- Partner description
- UniProt: Q9NPB9; Gene: ackr4_human; Family: Chemokine
- Interactions detected
- 88
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ALA 1 | NTc.Cm32 | TRP 97 | 2.60x60 | Hydrophobic |
| ALA 1 | NTc.Cm32 | TRP 97 | 2.60x60 | VdWContact |
| ALA 1 | NTc.Cm32 | TYR 119 | 3.32x32 | Hydrophobic |
| ARG 2 | NTc.Cm31 | GLN 201 | 5.39x40 | HBDonor |
| ARG 2 | NTc.Cm31 | GLN 201 | 5.39x40 | VdWContact |
| ARG 2 | NTc.Cm31 | GLU 204 | 5.42x43 | Cationic |
| ARG 2 | NTc.Cm31 | GLU 204 | 5.42x43 | HBDonor |
| ARG 2 | NTc.Cm31 | GLU 204 | 5.42x43 | VdWContact |
| ARG 2 | NTc.Cm31 | LYS 260 | 6.55x55 | VdWContact |
| ARG 2 | NTc.Cm31 | ILE 285 | 7.35x34 | Hydrophobic |
| ARG 2 | NTc.Cm31 | GLU 289 | 7.39x38 | HBDonor |
| ARG 2 | NTc.Cm31 | GLU 289 | 7.39x38 | VdWContact |
| GLY 3 | NTc.Cm30 | GLN 286 | 7.36x35 | HBAcceptor |
| GLY 3 | NTc.Cm30 | GLN 286 | 7.36x35 | VdWContact |
| GLY 3 | NTc.Cm30 | GLU 289 | 7.39x38 | HBDonor |
| GLY 3 | NTc.Cm30 | GLU 289 | 7.39x38 | VdWContact |
| THR 4 | NTc.Cm29 | LEU 44 | 1.35x35 | Hydrophobic |
| THR 4 | NTc.Cm29 | TRP 97 | 2.60x60 | Hydrophobic |
| THR 4 | NTc.Cm29 | ASN 100 | 2.63x63 | VdWContact |
| THR 4 | NTc.Cm29 | ALA 101 | 2.64x64 | Hydrophobic |
| ASN 5 | NTc.Cm28 | CYS 184 | 45.50x50 | HBDonor |
| ASN 5 | NTc.Cm28 | CYS 184 | 45.50x50 | VdWContact |
| ASN 5 | NTc.Cm28 | ILE 185 | 45.51x51 | Hydrophobic |
| VAL 6 | NTc.Cm27 | VAL 36 | 1.27x27 | Hydrophobic |
| VAL 6 | NTc.Cm27 | ARG 263 | 6.58x58 | VdWContact |
| VAL 6 | NTc.Cm27 | ASP 282 | 7.32x31 | Hydrophobic |
| VAL 6 | NTc.Cm27 | ASP 282 | 7.32x31 | VdWContact |
| VAL 6 | NTc.Cm27 | ILE 285 | 7.35x34 | Hydrophobic |
| VAL 6 | NTc.Cm27 | ILE 285 | 7.35x34 | VdWContact |
| VAL 6 | NTc.Cm27 | GLN 286 | 7.36x35 | Hydrophobic |
| VAL 6 | NTc.Cm27 | GLN 286 | 7.36x35 | VdWContact |
| GLY 7 | NTc.Cm26 | LYS 33 | - | VdWContact |
| GLY 7 | NTc.Cm26 | ARG 37 | 1.28x28 | HBAcceptor |
| GLY 7 | NTc.Cm26 | ARG 37 | 1.28x28 | VdWContact |
| GLY 7 | NTc.Cm26 | ASP 282 | 7.32x31 | HBDonor |
| GLY 7 | NTc.Cm26 | ASP 282 | 7.32x31 | VdWContact |
| ARG 8 | NTc.Cm25 | LYS 33 | - | VdWContact |
| ARG 8 | NTc.Cm25 | ILE 185 | 45.51x51 | VdWContact |
| GLU 9 | NTc.Cm24 | ILE 30 | - | Hydrophobic |
| GLU 9 | NTc.Cm24 | CYS 31 | - | VdWContact |
| GLU 9 | NTc.Cm24 | ILE 32 | - | VdWContact |
| GLU 9 | NTc.Cm24 | ARG 37 | 1.28x28 | Anionic |
| GLU 9 | NTc.Cm24 | ARG 37 | 1.28x28 | HBAcceptor |
| GLU 9 | NTc.Cm24 | ARG 37 | 1.28x28 | VdWContact |
| CYS 10 | NTc.Cm23 | CYS 31 | - | HBAcceptor |
| CYS 10 | NTc.Cm23 | CYS 31 | - | VdWContact |
| LEU 12 | NTc.Cm21 | LEU 29 | - | HBDonor |
| LEU 12 | NTc.Cm21 | LEU 29 | - | VdWContact |
| LEU 12 | NTc.Cm21 | CYS 31 | - | Hydrophobic |
| LEU 12 | NTc.Cm21 | CYS 31 | - | VdWContact |
| LEU 12 | NTc.Cm21 | SER 274 | 7.24x23 | VdWContact |
| LEU 12 | NTc.Cm21 | CYS 275 | 7.25x24 | Hydrophobic |
| LEU 12 | NTc.Cm21 | CYS 275 | 7.25x24 | VdWContact |
| GLU 13 | NTc.Cm20 | LEU 29 | - | Hydrophobic |
| GLU 13 | NTc.Cm20 | LEU 29 | - | VdWContact |
| PHE 15 | NTc.Cm18 | TYR 27 | - | Hydrophobic |
| PHE 15 | NTc.Cm18 | TYR 27 | - | PiStacking |
| PHE 15 | NTc.Cm18 | TYR 27 | - | VdWContact |
| PHE 15 | NTc.Cm18 | LEU 29 | - | Hydrophobic |
| PRO 20 | NTc.Cm13 | MET 18 | - | Hydrophobic |
| PRO 20 | NTc.Cm13 | MET 18 | - | VdWContact |
| PRO 20 | NTc.Cm13 | TYR 24 | - | Hydrophobic |
| PRO 20 | NTc.Cm13 | TYR 24 | - | VdWContact |
| LEU 21 | NTc.Cm12 | TYR 13 | - | Hydrophobic |
| ARG 22 | NTc.Cm11 | TYR 13 | - | Hydrophobic |
| ARG 22 | NTc.Cm11 | GLU 15 | - | Cationic |
| ARG 22 | NTc.Cm11 | GLU 15 | - | HBDonor |
| ARG 22 | NTc.Cm11 | GLU 15 | - | VdWContact |
| TYR 28 | NTc.Cm5 | ILE 30 | - | Hydrophobic |
| TYR 28 | NTc.Cm5 | ILE 30 | - | VdWContact |
| GLN 29 | NTc.Cm4 | ARG 190 | - | VdWContact |
| GLU 32 | NTc.Cm1 | ILE 187 | - | Hydrophobic |
| GLU 32 | NTc.Cm1 | ILE 187 | - | VdWContact |
| ARG 36 | cxb1.2 | SER 270 | - | VdWContact |
| ASP 37 | cxb1.5 | ARG 190 | - | Anionic |
| ASP 37 | cxb1.5 | ARG 190 | - | HBAcceptor |
| ASP 37 | cxb1.5 | ARG 190 | - | VdWContact |
| VAL 40 | cxb1.8 | ILE 30 | - | Hydrophobic |
| ARG 47 | B1.2 | TYR 24 | - | HBDonor |
| ARG 47 | B1.2 | TYR 24 | - | VdWContact |
| ARG 47 | B1.2 | SER 25 | - | VdWContact |
| ALA 48 | B1.3 | TYR 27 | - | VdWContact |
| ALA 48 | B1.3 | ILE 30 | - | Hydrophobic |
| ILE 49 | B1.4 | TYR 24 | - | Hydrophobic |
| ILE 49 | B1.4 | TYR 27 | - | Hydrophobic |
| ILE 49 | B1.4 | TYR 27 | - | VdWContact |
| CYS 50 | B1.5 | LEU 29 | - | Hydrophobic |
| CYS 50 | B1.5 | LEU 29 | - | VdWContact |
