Predicted complex interactions
CCL18_HUMAN + ACKR4
SUMMARY
- Chemokine
- CCL18_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- ACKR4 View partner entry
- Partner description
- UniProt: Q9NPB9; Gene: ackr4_human; Family: Chemokine
- Interactions detected
- 62
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| THR 5 | NTc.Cm25 | ASN 181 | - | HBAcceptor |
| THR 5 | NTc.Cm25 | ASN 181 | - | VdWContact |
| GLU 8 | NTc.Cm22 | LYS 33 | - | HBAcceptor |
| GLU 8 | NTc.Cm22 | LYS 33 | - | Hydrophobic |
| GLU 8 | NTc.Cm22 | LYS 33 | - | VdWContact |
| GLU 8 | NTc.Cm22 | ARG 37 | 1.28x28 | Anionic |
| GLU 8 | NTc.Cm22 | ARG 37 | 1.28x28 | VdWContact |
| GLU 8 | NTc.Cm22 | ARG 183 | - | Anionic |
| GLU 8 | NTc.Cm22 | ARG 183 | - | HBAcceptor |
| GLU 8 | NTc.Cm22 | ARG 183 | - | VdWContact |
| LEU 9 | NTc.Cm21 | ILE 30 | - | Hydrophobic |
| LEU 9 | NTc.Cm21 | ILE 30 | - | VdWContact |
| LEU 9 | NTc.Cm21 | ILE 32 | - | Hydrophobic |
| LEU 9 | NTc.Cm21 | ILE 32 | - | VdWContact |
| CYS 10 | NTc.Cm20 | CYS 31 | - | HBAcceptor |
| CYS 10 | NTc.Cm20 | CYS 31 | - | HBDonor |
| CYS 10 | NTc.Cm20 | CYS 31 | - | Hydrophobic |
| CYS 10 | NTc.Cm20 | CYS 31 | - | VdWContact |
| CYS 10 | NTc.Cm20 | LYS 33 | - | Anionic |
| LEU 12 | NTc.Cm18 | LEU 29 | - | Hydrophobic |
| LEU 12 | NTc.Cm18 | LEU 29 | - | VdWContact |
| LEU 12 | NTc.Cm18 | CYS 31 | - | Hydrophobic |
| LEU 12 | NTc.Cm18 | CYS 275 | 7.25x24 | Hydrophobic |
| LEU 12 | NTc.Cm18 | CYS 275 | 7.25x24 | VdWContact |
| LEU 12 | NTc.Cm18 | SER 278 | 7.28x27 | VdWContact |
| VAL 13 | NTc.Cm17 | LEU 29 | - | Hydrophobic |
| VAL 13 | NTc.Cm17 | LEU 29 | - | VdWContact |
| VAL 13 | NTc.Cm17 | THR 273 | - | Hydrophobic |
| THR 15 | NTc.Cm15 | TYR 27 | - | VdWContact |
| TRP 17 | NTc.Cm13 | TYR 22 | - | Hydrophobic |
| TRP 17 | NTc.Cm13 | TYR 22 | - | VdWContact |
| TRP 17 | NTc.Cm13 | TYR 27 | - | Hydrophobic |
| TRP 17 | NTc.Cm13 | TYR 27 | - | VdWContact |
| LYS 22 | NTc.Cm8 | GLU 14 | - | Cationic |
| LYS 22 | NTc.Cm8 | GLU 14 | - | HBDonor |
| LYS 22 | NTc.Cm8 | GLU 14 | - | VdWContact |
| PHE 23 | NTc.Cm7 | GLU 14 | - | Hydrophobic |
| PHE 23 | NTc.Cm7 | GLU 14 | - | VdWContact |
| PHE 23 | NTc.Cm7 | MET 18 | - | Hydrophobic |
| PHE 23 | NTc.Cm7 | MET 18 | - | VdWContact |
| GLU 29 | NTc.Cm1 | ARG 190 | - | Anionic |
| GLU 29 | NTc.Cm1 | ARG 190 | - | HBAcceptor |
| GLU 29 | NTc.Cm1 | ARG 190 | - | VdWContact |
| PRO 32 | cxb1.1 | ILE 185 | 45.51x51 | Hydrophobic |
| PRO 32 | cxb1.1 | ILE 187 | - | Hydrophobic |
| PRO 32 | cxb1.1 | ILE 187 | - | VdWContact |
| GLN 33 | cxb1.2 | ILE 185 | 45.51x51 | Hydrophobic |
| GLN 33 | cxb1.2 | ILE 185 | 45.51x51 | VdWContact |
| LYS 36 | cxb1.7 | SER 270 | - | HBDonor |
| LYS 36 | cxb1.7 | SER 270 | - | VdWContact |
| ILE 40 | cxb1.14 | ILE 30 | - | Hydrophobic |
| ARG 45 | B1.3 | GLU 15 | - | Cationic |
| ARG 45 | B1.3 | GLU 15 | - | HBDonor |
| ARG 45 | B1.3 | GLU 15 | - | VdWContact |
| ARG 47 | B1.5 | TYR 24 | - | CationPi |
| ARG 47 | B1.5 | TYR 24 | - | VdWContact |
| GLN 48 | B1.6 | ILE 30 | - | Hydrophobic |
| GLN 48 | B1.6 | ILE 30 | - | VdWContact |
| ILE 49 | B1.7 | TYR 24 | - | Hydrophobic |
| ILE 49 | B1.7 | TYR 27 | - | Hydrophobic |
| ILE 49 | B1.7 | TYR 27 | - | VdWContact |
| CYS 50 | b1b2.4 | ILE 30 | - | VdWContact |
