Predicted complex interactions
CCL19_HUMAN + ACKR4
SUMMARY
- Chemokine
- CCL19_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- ACKR4 View partner entry
- Partner description
- UniProt: Q9NPB9; Gene: ackr4_human; Family: Chemokine
- Interactions detected
- 87
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLY 1 | NTc.Cm28 | TYR 119 | 3.32x32 | CationPi |
| GLY 1 | NTc.Cm28 | GLU 289 | 7.39x38 | Cationic |
| GLY 1 | NTc.Cm28 | GLU 289 | 7.39x38 | HBDonor |
| GLY 1 | NTc.Cm28 | GLU 289 | 7.39x38 | VdWContact |
| THR 2 | NTc.Cm27 | TRP 97 | 2.60x60 | Hydrophobic |
| THR 2 | NTc.Cm27 | TRP 97 | 2.60x60 | VdWContact |
| ASN 3 | NTc.Cm26 | ARG 263 | 6.58x58 | VdWContact |
| ASP 4 | NTc.Cm25 | ARG 183 | - | Hydrophobic |
| ASP 4 | NTc.Cm25 | ARG 183 | - | VdWContact |
| ASP 4 | NTc.Cm25 | CYS 184 | 45.50x50 | HBAcceptor |
| ASP 4 | NTc.Cm25 | CYS 184 | 45.50x50 | VdWContact |
| ASP 4 | NTc.Cm25 | ILE 185 | 45.51x51 | Hydrophobic |
| ALA 5 | NTc.Cm24 | LYS 33 | - | Hydrophobic |
| ALA 5 | NTc.Cm24 | LYS 33 | - | VdWContact |
| ALA 5 | NTc.Cm24 | VAL 36 | 1.27x27 | Hydrophobic |
| ALA 5 | NTc.Cm24 | ARG 37 | 1.28x28 | HBAcceptor |
| ALA 5 | NTc.Cm24 | ARG 37 | 1.28x28 | Hydrophobic |
| ALA 5 | NTc.Cm24 | ARG 37 | 1.28x28 | VdWContact |
| ALA 5 | NTc.Cm24 | ASP 282 | 7.32x31 | Hydrophobic |
| GLU 6 | NTc.Cm23 | ASN 179 | - | HBAcceptor |
| GLU 6 | NTc.Cm23 | ASN 179 | - | VdWContact |
| GLU 6 | NTc.Cm23 | ARG 183 | - | Anionic |
| GLU 6 | NTc.Cm23 | ARG 183 | - | HBAcceptor |
| GLU 6 | NTc.Cm23 | ARG 183 | - | VdWContact |
| ASP 7 | NTc.Cm22 | ILE 30 | - | Hydrophobic |
| ASP 7 | NTc.Cm22 | CYS 31 | - | VdWContact |
| ASP 7 | NTc.Cm22 | ILE 32 | - | VdWContact |
| ASP 7 | NTc.Cm22 | LYS 33 | - | HBAcceptor |
| ASP 7 | NTc.Cm22 | LYS 33 | - | VdWContact |
| ASP 7 | NTc.Cm22 | ARG 37 | 1.28x28 | Anionic |
| ASP 7 | NTc.Cm22 | ARG 37 | 1.28x28 | HBAcceptor |
| ASP 7 | NTc.Cm22 | ARG 37 | 1.28x28 | VdWContact |
| CYS 8 | NTc.Cm21 | CYS 31 | - | HBAcceptor |
| CYS 8 | NTc.Cm21 | CYS 31 | - | VdWContact |
| LEU 10 | NTc.Cm19 | CYS 31 | - | Hydrophobic |
| LEU 10 | NTc.Cm19 | CYS 275 | 7.25x24 | Hydrophobic |
| LEU 10 | NTc.Cm19 | CYS 275 | 7.25x24 | VdWContact |
| LEU 10 | NTc.Cm19 | SER 278 | 7.28x27 | VdWContact |
| SER 11 | NTc.Cm18 | GLU 28 | - | VdWContact |
| THR 13 | NTc.Cm16 | TYR 27 | - | Hydrophobic |
| THR 13 | NTc.Cm16 | GLU 28 | - | VdWContact |
| LYS 15 | NTc.Cm14 | GLN 26 | - | HBDonor |
| LYS 15 | NTc.Cm14 | GLN 26 | - | VdWContact |
| LYS 15 | NTc.Cm14 | TYR 27 | - | Hydrophobic |
| PRO 16 | NTc.Cm13 | TYR 27 | - | HBAcceptor |
| PRO 16 | NTc.Cm13 | TYR 27 | - | VdWContact |
| ILE 17 | NTc.Cm12 | TYR 27 | - | Hydrophobic |
| ILE 17 | NTc.Cm12 | TYR 27 | - | VdWContact |
| PRO 18 | NTc.Cm11 | TYR 22 | - | Hydrophobic |
| PRO 18 | NTc.Cm11 | TYR 22 | - | VdWContact |
| PRO 18 | NTc.Cm11 | TYR 27 | - | VdWContact |
| TYR 20 | NTc.Cm9 | GLU 17 | - | HBDonor |
| TYR 20 | NTc.Cm9 | GLU 17 | - | Hydrophobic |
| TYR 20 | NTc.Cm9 | GLU 17 | - | VdWContact |
| ILE 21 | NTc.Cm8 | TYR 22 | - | Hydrophobic |
| ILE 21 | NTc.Cm8 | TYR 22 | - | VdWContact |
| ILE 21 | NTc.Cm8 | TYR 24 | - | Hydrophobic |
| ILE 21 | NTc.Cm8 | TYR 24 | - | VdWContact |
| LEU 28 | NTc.Cm1 | ILE 30 | - | Hydrophobic |
| ILE 30 | CX.5 | ARG 190 | - | Hydrophobic |
| ILE 30 | CX.5 | ARG 190 | - | VdWContact |
| LYS 31 | cxb1.1 | ASP 180 | - | Cationic |
| LYS 31 | cxb1.1 | ILE 187 | - | VdWContact |
| GLY 33 | cxb1.5 | ILE 185 | 45.51x51 | VdWContact |
| ARG 35 | cxb1.8 | ASP 266 | 6.61x61 | Cationic |
| ARG 35 | cxb1.8 | ASP 266 | 6.61x61 | HBDonor |
| ARG 35 | cxb1.8 | ASP 266 | 6.61x61 | VdWContact |
| VAL 40 | cxb1.15 | ILE 30 | - | Hydrophobic |
| THR 43 | B1.2 | TYR 24 | - | Hydrophobic |
| THR 43 | B1.2 | TYR 24 | - | VdWContact |
| ARG 45 | B1.4 | MET 18 | - | HBDonor |
| ARG 45 | B1.4 | MET 18 | - | VdWContact |
| ARG 45 | B1.4 | GLY 20 | - | VdWContact |
| ARG 45 | B1.4 | THR 21 | - | VdWContact |
| ARG 47 | B1.6 | TYR 24 | - | VdWContact |
| ARG 47 | B1.6 | LEU 29 | - | Hydrophobic |
| GLN 48 | B1.7 | ILE 30 | - | HBAcceptor |
| GLN 48 | B1.7 | ILE 30 | - | Hydrophobic |
| GLN 48 | B1.7 | ILE 30 | - | VdWContact |
| LEU 49 | b1b2.4 | TYR 24 | - | Hydrophobic |
| LEU 49 | b1b2.4 | TYR 27 | - | Hydrophobic |
| LEU 49 | b1b2.4 | LEU 29 | - | Hydrophobic |
| LEU 49 | b1b2.4 | LEU 29 | - | VdWContact |
| CYS 50 | b1b2.6 | GLU 28 | - | HBDonor |
| CYS 50 | b1b2.6 | GLU 28 | - | Hydrophobic |
| CYS 50 | b1b2.6 | GLU 28 | - | VdWContact |
| CYS 50 | b1b2.6 | ILE 30 | - | VdWContact |
