Predicted complex interactions
CCL21_HUMAN + ACKR4
SUMMARY
- Chemokine
- CCL21_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- ACKR4 View partner entry
- Partner description
- UniProt: Q9NPB9; Gene: ackr4_human; Family: Chemokine
- Interactions detected
- 101
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| SER 1 | NTc.Cm30 | TYR 176 | 4.64x65 | HBAcceptor |
| SER 1 | NTc.Cm30 | TYR 176 | 4.64x65 | VdWContact |
| SER 1 | NTc.Cm30 | GLU 289 | 7.39x38 | Cationic |
| SER 1 | NTc.Cm30 | GLU 289 | 7.39x38 | HBDonor |
| SER 1 | NTc.Cm30 | GLU 289 | 7.39x38 | VdWContact |
| ASP 2 | NTc.Cm29 | ARG 263 | 6.58x58 | HBAcceptor |
| ASP 2 | NTc.Cm29 | ARG 263 | 6.58x58 | VdWContact |
| ASP 2 | NTc.Cm29 | ILE 285 | 7.35x34 | Hydrophobic |
| ASP 2 | NTc.Cm29 | ILE 285 | 7.35x34 | VdWContact |
| ASP 2 | NTc.Cm29 | GLN 286 | 7.36x35 | HBAcceptor |
| ASP 2 | NTc.Cm29 | GLN 286 | 7.36x35 | Hydrophobic |
| ASP 2 | NTc.Cm29 | GLN 286 | 7.36x35 | VdWContact |
| GLY 3 | NTc.Cm28 | ILE 185 | 45.51x51 | VdWContact |
| GLY 4 | NTc.Cm27 | ARG 183 | - | HBAcceptor |
| GLY 4 | NTc.Cm27 | ARG 183 | - | VdWContact |
| ALA 5 | NTc.Cm26 | VAL 36 | 1.27x27 | Hydrophobic |
| ALA 5 | NTc.Cm26 | ARG 37 | 1.28x28 | HBAcceptor |
| ALA 5 | NTc.Cm26 | ARG 37 | 1.28x28 | Hydrophobic |
| ALA 5 | NTc.Cm26 | ARG 37 | 1.28x28 | VdWContact |
| ALA 5 | NTc.Cm26 | ARG 183 | - | HBAcceptor |
| ALA 5 | NTc.Cm26 | ARG 183 | - | VdWContact |
| ALA 5 | NTc.Cm26 | ASP 282 | 7.32x31 | Hydrophobic |
| GLN 6 | NTc.Cm25 | ASN 179 | - | HBAcceptor |
| GLN 6 | NTc.Cm25 | ASN 179 | - | VdWContact |
| GLN 6 | NTc.Cm25 | ARG 183 | - | VdWContact |
| GLN 6 | NTc.Cm25 | ILE 185 | 45.51x51 | VdWContact |
| ASP 7 | NTc.Cm24 | ILE 30 | - | Hydrophobic |
| ASP 7 | NTc.Cm24 | CYS 31 | - | VdWContact |
| ASP 7 | NTc.Cm24 | LYS 33 | - | HBAcceptor |
| ASP 7 | NTc.Cm24 | LYS 33 | - | VdWContact |
| ASP 7 | NTc.Cm24 | ARG 37 | 1.28x28 | Anionic |
| ASP 7 | NTc.Cm24 | ARG 37 | 1.28x28 | HBAcceptor |
| ASP 7 | NTc.Cm24 | ARG 37 | 1.28x28 | VdWContact |
| LEU 10 | NTc.Cm21 | CYS 31 | - | Hydrophobic |
| LEU 10 | NTc.Cm21 | CYS 275 | 7.25x24 | Hydrophobic |
| LEU 10 | NTc.Cm21 | CYS 275 | 7.25x24 | VdWContact |
| LYS 11 | NTc.Cm20 | GLU 28 | - | Hydrophobic |
| LYS 11 | NTc.Cm20 | THR 273 | - | VdWContact |
| TYR 12 | NTc.Cm19 | GLU 28 | - | VdWContact |
| SER 13 | NTc.Cm18 | TYR 27 | - | VdWContact |
| ARG 15 | NTc.Cm16 | GLN 26 | - | HBDonor |
| ARG 15 | NTc.Cm16 | GLN 26 | - | VdWContact |
| ARG 15 | NTc.Cm16 | TYR 27 | - | Hydrophobic |
| LYS 16 | NTc.Cm15 | TYR 27 | - | HBAcceptor |
| LYS 16 | NTc.Cm15 | TYR 27 | - | VdWContact |
| ILE 17 | NTc.Cm14 | TYR 27 | - | Hydrophobic |
| PRO 18 | NTc.Cm13 | TYR 22 | - | Hydrophobic |
| PRO 18 | NTc.Cm13 | TYR 27 | - | VdWContact |
| ALA 19 | NTc.Cm12 | TYR 11 | - | Hydrophobic |
| ALA 19 | NTc.Cm12 | TYR 11 | - | VdWContact |
| LYS 20 | NTc.Cm11 | GLU 14 | - | Cationic |
| LYS 20 | NTc.Cm11 | GLU 14 | - | HBDonor |
| LYS 20 | NTc.Cm11 | GLU 14 | - | Hydrophobic |
| LYS 20 | NTc.Cm11 | GLU 14 | - | VdWContact |
| LYS 20 | NTc.Cm11 | MET 18 | - | Hydrophobic |
| LYS 20 | NTc.Cm11 | MET 18 | - | VdWContact |
| VAL 21 | NTc.Cm10 | MET 18 | - | Hydrophobic |
| VAL 21 | NTc.Cm10 | TYR 22 | - | Hydrophobic |
| VAL 21 | NTc.Cm10 | TYR 22 | - | VdWContact |
| VAL 21 | NTc.Cm10 | TYR 24 | - | Hydrophobic |
| LYS 27 | NTc.Cm4 | ARG 190 | - | VdWContact |
| GLU 29 | NTc.Cm2 | ILE 187 | - | Hydrophobic |
| GLU 29 | NTc.Cm2 | ARG 190 | - | Anionic |
| GLU 29 | NTc.Cm2 | ARG 190 | - | HBAcceptor |
| GLU 29 | NTc.Cm2 | ARG 190 | - | VdWContact |
| PRO 30 | NTc.Cm1 | LYS 197 | 5.35x36 | VdWContact |
| SER 31 | CX.1 | PRO 186 | 45.52x52 | VdWContact |
| LEU 32 | CX.5 | PRO 186 | 45.52x52 | Hydrophobic |
| LEU 32 | CX.5 | PRO 186 | 45.52x52 | VdWContact |
| LEU 32 | CX.5 | GLN 201 | 5.39x40 | Hydrophobic |
| LEU 32 | CX.5 | ILE 267 | 6.62x62 | Hydrophobic |
| LEU 32 | CX.5 | ILE 267 | 6.62x62 | VdWContact |
| SER 35 | cxb1.5 | ASP 266 | 6.61x61 | HBDonor |
| LEU 40 | cxb1.11 | ILE 30 | - | Hydrophobic |
| LEU 40 | cxb1.11 | ILE 30 | - | VdWContact |
| PRO 43 | cxb1.16 | TYR 24 | - | Hydrophobic |
| PRO 43 | cxb1.16 | TYR 24 | - | VdWContact |
| ARG 44 | B1.1 | MET 18 | - | VdWContact |
| LYS 45 | B1.2 | TYR 24 | - | Hydrophobic |
| GLN 48 | B1.5 | TYR 24 | - | Hydrophobic |
| GLN 48 | B1.5 | TYR 24 | - | VdWContact |
| ALA 49 | B1.6 | LEU 29 | - | Hydrophobic |
| ALA 49 | B1.6 | ILE 30 | - | Hydrophobic |
| ALA 49 | B1.6 | ILE 30 | - | VdWContact |
| ALA 49 | B1.6 | ILE 32 | - | Hydrophobic |
| GLU 50 | B1.7 | ILE 30 | - | HBAcceptor |
| GLU 50 | B1.7 | ILE 30 | - | Hydrophobic |
| GLU 50 | B1.7 | ILE 30 | - | VdWContact |
| LEU 51 | b1b2.4 | TYR 24 | - | Hydrophobic |
| LEU 51 | b1b2.4 | TYR 27 | - | Hydrophobic |
| LEU 51 | b1b2.4 | TYR 27 | - | VdWContact |
| LEU 51 | b1b2.4 | LEU 29 | - | Hydrophobic |
| CYS 52 | b1b2.6 | GLU 28 | - | HBDonor |
| CYS 52 | b1b2.6 | GLU 28 | - | Hydrophobic |
| CYS 52 | b1b2.6 | GLU 28 | - | VdWContact |
| CYS 52 | b1b2.6 | ILE 30 | - | VdWContact |
| HIS 66 | B2.6 | TYR 11 | - | Hydrophobic |
| LYS 75 | B3.3 | ASP 180 | - | Cationic |
| LYS 75 | B3.3 | ASP 180 | - | HBDonor |
| LYS 75 | B3.3 | ASP 180 | - | Hydrophobic |
| LYS 75 | B3.3 | ASP 180 | - | VdWContact |
