Predicted complex interactions
CCL22_HUMAN + ACKR4
SUMMARY
- Chemokine
- CCL22_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- ACKR4 View partner entry
- Partner description
- UniProt: Q9NPB9; Gene: ackr4_human; Family: Chemokine
- Interactions detected
- 88
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLY 1 | NTc.Cm35 | GLU 289 | 7.39x38 | Cationic |
| GLY 1 | NTc.Cm35 | GLU 289 | 7.39x38 | HBDonor |
| GLY 1 | NTc.Cm35 | GLU 289 | 7.39x38 | VdWContact |
| PRO 2 | NTc.Cm34 | TRP 97 | 2.60x60 | Hydrophobic |
| PRO 2 | NTc.Cm34 | TYR 119 | 3.32x32 | Hydrophobic |
| PRO 2 | NTc.Cm34 | TYR 176 | 4.64x65 | Hydrophobic |
| PRO 2 | NTc.Cm34 | TYR 176 | 4.64x65 | VdWContact |
| TYR 3 | NTc.Cm33 | ILE 285 | 7.35x34 | Hydrophobic |
| GLY 4 | NTc.Cm32 | GLN 286 | 7.36x35 | HBAcceptor |
| GLY 4 | NTc.Cm32 | GLN 286 | 7.36x35 | VdWContact |
| GLY 4 | NTc.Cm32 | GLU 289 | 7.39x38 | HBDonor |
| GLY 4 | NTc.Cm32 | GLU 289 | 7.39x38 | VdWContact |
| ALA 5 | NTc.Cm31 | LEU 44 | 1.35x35 | Hydrophobic |
| ALA 5 | NTc.Cm31 | ALA 101 | 2.64x64 | Hydrophobic |
| ASN 6 | NTc.Cm30 | TRP 97 | 2.60x60 | VdWContact |
| ASN 6 | NTc.Cm30 | ASN 100 | 2.63x63 | HBAcceptor |
| ASN 6 | NTc.Cm30 | ASN 100 | 2.63x63 | VdWContact |
| ASN 6 | NTc.Cm30 | CYS 184 | 45.50x50 | VdWContact |
| ASN 6 | NTc.Cm30 | ILE 185 | 45.51x51 | Hydrophobic |
| ASN 6 | NTc.Cm30 | ILE 185 | 45.51x51 | VdWContact |
| MET 7 | NTc.Cm29 | ARG 263 | 6.58x58 | VdWContact |
| MET 7 | NTc.Cm29 | ASP 282 | 7.32x31 | Hydrophobic |
| MET 7 | NTc.Cm29 | ASP 282 | 7.32x31 | VdWContact |
| MET 7 | NTc.Cm29 | ILE 285 | 7.35x34 | Hydrophobic |
| MET 7 | NTc.Cm29 | ILE 285 | 7.35x34 | VdWContact |
| GLU 8 | NTc.Cm28 | ASN 179 | - | HBAcceptor |
| GLU 8 | NTc.Cm28 | ASN 179 | - | VdWContact |
| GLU 8 | NTc.Cm28 | ARG 183 | - | VdWContact |
| GLU 8 | NTc.Cm28 | ILE 185 | 45.51x51 | Hydrophobic |
| GLU 8 | NTc.Cm28 | ILE 185 | 45.51x51 | VdWContact |
| ASP 9 | NTc.Cm27 | ARG 37 | 1.28x28 | Anionic |
| ASP 9 | NTc.Cm27 | ARG 37 | 1.28x28 | VdWContact |
| ASP 9 | NTc.Cm27 | ARG 183 | - | Anionic |
| ASP 9 | NTc.Cm27 | ARG 183 | - | HBAcceptor |
| ASP 9 | NTc.Cm27 | ARG 183 | - | VdWContact |
| VAL 11 | NTc.Cm25 | ILE 30 | - | Hydrophobic |
| VAL 11 | NTc.Cm25 | ILE 30 | - | VdWContact |
| ARG 14 | NTc.Cm22 | CYS 31 | - | Cationic |
| ARG 14 | NTc.Cm22 | CYS 31 | - | VdWContact |
| ARG 14 | NTc.Cm22 | LYS 33 | - | VdWContact |
| ARG 14 | NTc.Cm22 | ILE 272 | - | VdWContact |
| ARG 14 | NTc.Cm22 | SER 274 | 7.24x23 | VdWContact |
| ARG 14 | NTc.Cm22 | CYS 275 | 7.25x24 | HBDonor |
| ARG 14 | NTc.Cm22 | CYS 275 | 7.25x24 | VdWContact |
| ARG 14 | NTc.Cm22 | SER 278 | 7.28x27 | VdWContact |
| ASP 15 | NTc.Cm21 | GLU 28 | - | HBDonor |
| ASP 15 | NTc.Cm21 | GLU 28 | - | Hydrophobic |
| ASP 15 | NTc.Cm21 | GLU 28 | - | VdWContact |
| VAL 17 | NTc.Cm19 | TYR 27 | - | Hydrophobic |
| VAL 17 | NTc.Cm19 | TYR 27 | - | VdWContact |
| TYR 19 | NTc.Cm17 | GLN 26 | - | VdWContact |
| LEU 21 | NTc.Cm15 | TYR 22 | - | Hydrophobic |
| LEU 21 | NTc.Cm15 | TYR 27 | - | Hydrophobic |
| PRO 22 | NTc.Cm14 | GLU 14 | - | VdWContact |
| PRO 22 | NTc.Cm14 | TYR 22 | - | Hydrophobic |
| PRO 22 | NTc.Cm14 | TYR 22 | - | VdWContact |
| ARG 24 | NTc.Cm12 | GLU 14 | - | Cationic |
| ARG 24 | NTc.Cm12 | GLU 14 | - | VdWContact |
| ARG 24 | NTc.Cm12 | GLU 17 | - | Cationic |
| ARG 24 | NTc.Cm12 | GLU 17 | - | HBDonor |
| ARG 24 | NTc.Cm12 | GLU 17 | - | VdWContact |
| ASP 34 | NTc.Cm2 | ILE 187 | - | Hydrophobic |
| ASP 34 | NTc.Cm2 | ILE 187 | - | VdWContact |
| ASP 34 | NTc.Cm2 | ARG 190 | - | Anionic |
| ASP 34 | NTc.Cm2 | ARG 190 | - | HBAcceptor |
| ASP 34 | NTc.Cm2 | ARG 190 | - | VdWContact |
| SER 35 | NTc.Cm1 | ILE 185 | 45.51x51 | VdWContact |
| PRO 37 | CX.5 | ILE 267 | 6.62x62 | Hydrophobic |
| ARG 38 | cxb1.1 | SER 270 | - | VdWContact |
| VAL 42 | cxb1.7 | ILE 30 | - | Hydrophobic |
| VAL 42 | cxb1.7 | ILE 30 | - | VdWContact |
| THR 45 | cxb1.11 | TYR 24 | - | Hydrophobic |
| THR 45 | cxb1.11 | TYR 24 | - | VdWContact |
| ARG 47 | cxb1.15 | THR 21 | - | VdWContact |
| ARG 47 | cxb1.15 | TYR 24 | - | Hydrophobic |
| ARG 47 | cxb1.15 | TYR 24 | - | VdWContact |
| LYS 49 | B1.1 | TYR 24 | - | Hydrophobic |
| LYS 49 | B1.1 | TYR 24 | - | VdWContact |
| LYS 49 | B1.1 | LEU 29 | - | Hydrophobic |
| GLU 50 | B1.2 | LEU 29 | - | VdWContact |
| GLU 50 | B1.2 | ILE 30 | - | Hydrophobic |
| GLU 50 | B1.2 | ILE 30 | - | VdWContact |
| ILE 51 | B1.3 | TYR 24 | - | Hydrophobic |
| ILE 51 | B1.3 | TYR 24 | - | VdWContact |
| ILE 51 | B1.3 | TYR 27 | - | Hydrophobic |
| ILE 51 | B1.3 | TYR 27 | - | VdWContact |
| CYS 52 | B1.4 | GLU 28 | - | VdWContact |
| CYS 52 | B1.4 | ILE 30 | - | VdWContact |
