Predicted complex interactions
CCL23_HUMAN + ACKR4
SUMMARY
- Chemokine
- CCL23_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- ACKR4 View partner entry
- Partner description
- UniProt: Q9NPB9; Gene: ackr4_human; Family: Chemokine
- Interactions detected
- 89
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ASP 24 | NTc.Cm47 | ARG 183 | - | HBAcceptor |
| ASP 24 | NTc.Cm47 | ARG 183 | - | VdWContact |
| ARG 25 | NTc.Cm46 | ASP 180 | - | VdWContact |
| ARG 25 | NTc.Cm46 | ASN 181 | - | Hydrophobic |
| ARG 25 | NTc.Cm46 | ASN 181 | - | VdWContact |
| ARG 25 | NTc.Cm46 | ARG 183 | - | HBAcceptor |
| ARG 25 | NTc.Cm46 | ARG 183 | - | VdWContact |
| PHE 26 | NTc.Cm45 | HIS 103 | 2.66x66 | VdWContact |
| PHE 26 | NTc.Cm45 | GLY 104 | 23.49x49 | VdWContact |
| PHE 26 | NTc.Cm45 | ALA 182 | - | Hydrophobic |
| HIS 27 | NTc.Cm44 | ARG 37 | 1.28x28 | Hydrophobic |
| HIS 27 | NTc.Cm44 | ARG 37 | 1.28x28 | VdWContact |
| HIS 27 | NTc.Cm44 | LYS 41 | 1.32x32 | Hydrophobic |
| HIS 27 | NTc.Cm44 | LYS 41 | 1.32x32 | VdWContact |
| HIS 27 | NTc.Cm44 | VAL 102 | 2.65x65 | VdWContact |
| ALA 28 | NTc.Cm43 | ASN 100 | 2.63x63 | VdWContact |
| ALA 28 | NTc.Cm43 | ARG 183 | - | Hydrophobic |
| ALA 28 | NTc.Cm43 | ARG 183 | - | VdWContact |
| THR 29 | NTc.Cm42 | ALA 40 | 1.31x31 | Hydrophobic |
| THR 29 | NTc.Cm42 | ALA 40 | 1.31x31 | VdWContact |
| THR 29 | NTc.Cm42 | LEU 44 | 1.35x35 | Hydrophobic |
| THR 29 | NTc.Cm42 | GLN 286 | 7.36x35 | VdWContact |
| SER 30 | NTc.Cm41 | LYS 33 | - | VdWContact |
| SER 30 | NTc.Cm41 | ARG 37 | 1.28x28 | HBAcceptor |
| SER 30 | NTc.Cm41 | ARG 37 | 1.28x28 | VdWContact |
| SER 30 | NTc.Cm41 | ASP 282 | 7.32x31 | HBDonor |
| SER 30 | NTc.Cm41 | ASP 282 | 7.32x31 | VdWContact |
| ALA 31 | NTc.Cm40 | ARG 183 | - | VdWContact |
| ALA 31 | NTc.Cm40 | ILE 185 | 45.51x51 | Hydrophobic |
| ASP 32 | NTc.Cm39 | ILE 30 | - | Hydrophobic |
| ASP 32 | NTc.Cm39 | ILE 32 | - | VdWContact |
| ASP 32 | NTc.Cm39 | LYS 33 | - | HBAcceptor |
| ASP 32 | NTc.Cm39 | LYS 33 | - | VdWContact |
| ASP 32 | NTc.Cm39 | ARG 37 | 1.28x28 | Anionic |
| ASP 32 | NTc.Cm39 | ARG 37 | 1.28x28 | HBAcceptor |
| ASP 32 | NTc.Cm39 | ARG 37 | 1.28x28 | VdWContact |
| ASP 32 | NTc.Cm39 | ARG 183 | - | Anionic |
| ASP 32 | NTc.Cm39 | ARG 183 | - | HBAcceptor |
| ASP 32 | NTc.Cm39 | ARG 183 | - | VdWContact |
| CYS 33 | NTc.Cm38 | CYS 31 | - | HBAcceptor |
| CYS 33 | NTc.Cm38 | CYS 31 | - | HBDonor |
| CYS 33 | NTc.Cm38 | CYS 31 | - | VdWContact |
| CYS 33 | NTc.Cm38 | LYS 33 | - | Anionic |
| ILE 35 | NTc.Cm36 | LEU 29 | - | HBDonor |
| ILE 35 | NTc.Cm36 | LEU 29 | - | VdWContact |
| ILE 35 | NTc.Cm36 | CYS 31 | - | Hydrophobic |
| ILE 35 | NTc.Cm36 | THR 273 | - | VdWContact |
| SER 36 | NTc.Cm35 | LEU 29 | - | VdWContact |
| TYR 37 | NTc.Cm34 | LEU 29 | - | VdWContact |
| THR 38 | NTc.Cm33 | TYR 27 | - | VdWContact |
| THR 38 | NTc.Cm33 | LEU 29 | - | VdWContact |
| ARG 40 | NTc.Cm31 | TYR 22 | - | CationPi |
| ARG 40 | NTc.Cm31 | TYR 22 | - | Hydrophobic |
| ILE 42 | NTc.Cm29 | TYR 24 | - | Hydrophobic |
| ILE 42 | NTc.Cm29 | TYR 27 | - | Hydrophobic |
| PHE 51 | NTc.Cm20 | ASN 179 | - | VdWContact |
| GLU 52 | NTc.Cm19 | ASN 179 | - | HBAcceptor |
| GLU 52 | NTc.Cm19 | ASN 179 | - | VdWContact |
| GLU 52 | NTc.Cm19 | ILE 187 | - | Hydrophobic |
| GLU 52 | NTc.Cm19 | ARG 190 | - | Anionic |
| ASN 54 | NTc.Cm17 | ILE 185 | 45.51x51 | Hydrophobic |
| ASN 54 | NTc.Cm17 | PRO 186 | 45.52x52 | VdWContact |
| SER 55 | NTc.Cm16 | PRO 186 | 45.52x52 | HBDonor |
| SER 55 | NTc.Cm16 | PRO 186 | 45.52x52 | VdWContact |
| SER 55 | NTc.Cm16 | PHE 188 | - | HBAcceptor |
| SER 55 | NTc.Cm16 | PHE 188 | - | VdWContact |
| SER 55 | NTc.Cm16 | LYS 197 | 5.35x36 | VdWContact |
| GLU 56 | NTc.Cm15 | PRO 186 | 45.52x52 | Hydrophobic |
| GLU 56 | NTc.Cm15 | ARG 263 | 6.58x58 | Anionic |
| GLU 56 | NTc.Cm15 | ARG 263 | 6.58x58 | VdWContact |
| SER 58 | NTc.Cm13 | ASP 266 | 6.61x61 | HBDonor |
| SER 58 | NTc.Cm13 | ASP 266 | 6.61x61 | VdWContact |
| SER 58 | NTc.Cm13 | ILE 272 | - | VdWContact |
| ILE 63 | NTc.Cm8 | ILE 30 | - | Hydrophobic |
| ILE 63 | NTc.Cm8 | ILE 30 | - | VdWContact |
| ARG 70 | NTc.Cm1 | TYR 24 | - | Hydrophobic |
| ARG 70 | NTc.Cm1 | TYR 24 | - | VdWContact |
| ARG 71 | CX.1 | ILE 30 | - | Hydrophobic |
| ARG 71 | CX.1 | ILE 30 | - | VdWContact |
| PHE 72 | CX.5 | TYR 27 | - | Hydrophobic |
| PHE 72 | CX.5 | TYR 27 | - | VdWContact |
| PHE 72 | CX.5 | ILE 30 | - | VdWContact |
| CYS 73 | cxb1.1 | LEU 29 | - | Hydrophobic |
| CYS 73 | cxb1.1 | LEU 29 | - | VdWContact |
| CYS 73 | cxb1.1 | ILE 30 | - | Hydrophobic |
| CYS 73 | cxb1.1 | ILE 30 | - | VdWContact |
| PRO 76 | cxb1.6 | ARG 190 | - | VdWContact |
| GLN 82 | cxb1.15 | ARG 190 | - | VdWContact |
| MET 85 | B1.2 | ARG 190 | - | VdWContact |
